US08519255B2
The present invention provides a thermoelectric material and a method of manufacturing it. The thermoelectric material contains a half-Heusler compound including a composition represented by: (Ti1−aAa)1+x(Ni1−bBb)1+y(Sn1−cCc) where 0≦a<0.1, 0≦b<0.1 and 0≦c<0.1; −0.1≦x≦0.2 and 0
US08519246B2
A wheat cultivar, designated SJ909-371, is disclosed. The invention relates to the seeds, plants, and hybrids of wheat cultivar SJ909-371, and to methods for producing a wheat plant produced by crossing plants from wheat cultivar SJ909-371 with themselves or with plants from another wheat variety. The invention also relates to methods for producing a wheat plant containing in its genetic material one or more transgenes and to the transgenic wheat plants and plant parts produced by those methods. The invention also relates to wheat varieties or breeding varieties and plant parts derived from wheat cultivar SJ909-371, to methods for producing other wheat varieties, lines or plant parts derived from wheat cultivar SJ909-371, and to the wheat plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid wheat seeds and plants produced by crossing wheat cultivar SJ909-371 with another wheat cultivar.
US08519242B1
A novel maize variety designated X00B158 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X00B158 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X00B158 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X00B158, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X00B158. This invention further relates to methods for producing maize varieties derived from maize variety X00B158.
US08519240B1
A novel maize variety designated X03B465 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X03B465 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X03B465 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X03B465, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X03B465. This invention further relates to methods for producing maize varieties derived from maize variety X03B465.
US08519238B1
The present invention provides an inbred corn line designated NPFX5428, methods for producing a corn plant by crossing plants of the inbred line NPFX5428 with plants of another corn plant. The invention further encompasses all parts of inbred corn line NPFX5428, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line NPFX5428, and plants produced according to these methods.
US08519236B1
Basically, this invention provides for an inbred corn line designated NPFF6228, methods for producing a corn plant by crossing plants of the inbred line NPFF6228, with plants of another corn plant. The invention relates to the various parts of inbred NPFF6228, including culturable cells. This invention also relates to methods for introducing transgenic transgenes into inbred corn line NPFF6228, and plants produced by said methods.
US08519232B1
A novel soybean variety, designated XBP10001 is provided. Also provided are the seeds of soybean variety XBP10001, cells from soybean variety XBP10001, plants of soybean XBP10001, and plant parts of soybean variety XBP10001. Methods provided include producing a soybean plant by crossing soybean variety XBP10001 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP10001, methods for producing other soybean varieties or plant parts derived from soybean variety XBP10001, and methods of characterizing soybean variety XBP10001. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP10001 are further provided.
US08519230B2
A soybean cultivar designated 2522121658 is disclosed. The invention relates to the seeds of soybean cultivar 2522121658, to the plants of soybean 2522121658, to plant parts of soybean cultivar 2522121658, and to methods for producing a soybean plant produced by crossing soybean cultivar 2522121658 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety 2522121658, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 2522121658, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar 2522121658 with another soybean cultivar.
US08519227B2
There is provided an Agrobacterium transformation method for monocotyledons, comprising a step of infecting an intact seed.
US08519218B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH212179. The invention thus relates to the plants, seeds and tissue cultures of the variety CH212179, and to methods for producing a corn plant produced by crossing a corn plant of variety CH212179 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH212179.
US08519214B2
This invention provides for proteins which are expressed in the avian oviduct, packaged into eggs laid by the avian, then isolated.
US08519210B2
A process for the oxidative dehydrogenation of ethane is disclosed. The process may include: contacting an ethane feed and an oxygen-containing gas in the presence of an oxidative dehydrogenation catalyst in an oxidative dehydrogenation reaction zone under conditions to oxidatively dehydrogenate at least a portion of the ethane to produce a product stream comprising ethylene, carbon oxides, water, and unreacted oxygen and ethane, wherein an oxygen concentration in the product stream is at least 0.1 mol %; contacting the product stream with an oxygen elimination catalyst in an oxygen elimination reaction zone to combust at least a portion of the oxygen; recovering from the oxygen elimination reaction zone an effluent having a reduced oxygen content; separating water from the effluent; separating carbon oxides and any non-condensable gas(es) from the ethylene and the unreacted ethane; and separating the ethylene from the unreacted ethane.
US08519207B2
The present invention relates to a process for the hydrogenation, in particular selective hydrogenation of at least one unsaturated hydrocarbon compound comprising reacting the at least one unsaturated hydrocarbon compound with hydrogen in the presence of a hydrogenation catalyst, wherein the hydrogenation catalyst comprises a mixture of an ordered intermetallic compound and an inert material. According to another aspect, the present invention is concerned with the use of a mixture of at least one ordered intermetallic compound and at least one inert material, as a catalyst. The mixtures for use as a catalyst in the present invention can be prepared easily and achieve a superior activity in relation to the prior art, while preserving the high selectivity to the target compounds, e.g. in the selective hydrogenation of acetylene to ethylene.
US08519204B2
Processes and systems for stabilization and subsequent hydrogenation of an immiscible olefin are described. Methods of stabilizing a microbial-derived olefin composition are also described.
US08519202B2
Produce methyl chloride and sulfur dioxide using a reactor with lanthanum oxychloride, and contacting the lanthanum oxychloride with methanesulfonyl chloride under conditions sufficient to convert a portion of the methanesulfonyl chloride to methyl chloride and sulfur dioxide.
US08519181B2
The disclosure relates to a process for the preparation of acetic acid. The process comprises reacting a decanter heavy, organic phase of an acetic acid production process with acetic anhydride to convert acetaldehyde in the decanter heavy, organic phase to ethylidene diacetate and separating it from the decanter heavy, organic phase. Ethylidene diacetate can be hydrolyzed to recover acetic acid.
US08519169B2
A method of purifying 1α-hydroxy-20-methyl-2-methylene-19,24,25,26,27-pentanorvitamin D3 to obtain 1α-hydroxy-20-methyl-2-methylene-19,24,25,26,27-pentanorvitamin D3 in crystalline form. The method includes the steps of preparing a solvent of either ethyl formate or a mixture of ethyl formate and hexane, dissolving a product containing 1α-hydroxy-20-methyl-2-methylene-19,24,25,26,27-pentanorvitamin D3 to be purified in the solvent, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of 1α-hydroxy-20-methyl-2-methylene-19,24,25,26,27-pentanorvitamin D3 crystals, and recovering the 1α-hydroxy-20-methyl-2-methylene-19,24,25,26,27-pentanorvitamin D3 crystals.
US08519167B2
A method for the preparation of 2,5-furandicarboxylic acid (“FDCA”) and/or an alkyl ester of FDCA includes the step of contacting a feed comprising a starting material selected from 5-alkoxymethylfurfural, 2,5-di(alkoxymethyl)furan and a mixture thereof with an oxidant in the presence of an oxidation catalyst. The feed may also comprise 5-hydroxymethylfurfural as a further starting material.
US08519165B2
There is provided a process for the preparation of a compound of formula (I), wherein R1, R2, R3, R4, X and Y are as described in the description. Such compounds may, for example, be useful intermediates in the synthesis of drugs such as Dronedarone. Intermediate steps of the process comprise formulae according to (II) and (III).
US08519157B2
The present invention provides a method for producing of ultra-clean and high-purity N-methyl pyrrolidone through using industrial grade N-methyl pyrrolidone as raw material. After the pretreatment, sorption and dehydration with 4A molecular sieve, twice membrane filtrations are carried out through using β-cyclodextrin composite membrane for the first and 18-crown-6 composite membrane for the second. The filtrate is rectified under vacuum and filtered through using complexant composite microporous membrane to obtain the product. The ultra-clean and high-purity N-methyl pyrrolidone, produced by the method provided by the present invention, is up to the SEMI C8 standard. And the purity of the product is over 99.8%, the moisture content is less than 0.03%, and the content of single metal ion is less than 1 ppb. Comparing to the prior art, the present invention has the advantage such as the stable quality of the product, simple operation, and is suitable for industrial continuous production.
US08519155B2
The present invention relates to the choline and tromethamine salt of Licofelone.
US08519143B2
The present invention relates to derivatives of ((phenyl)-3,6-dihydropyridin-1-yl)(bridged piperazinyl)-1-alkanone derivatives and ((phenyl)-2,5-dihydropyrrol-1-yl) (bridged piperazinyl)-1-alkanone corresponding to Formula (I): in which the variables are as defined herein, to the preparation thereof and to the therapeutic use thereof.
US08519132B2
The invention concerns processes for oxidizing an alcohol to produce a carbonyl compound. The processes comprise contacting the alcohol with (i) a gaseous mixture comprising oxygen; and (ii) an amine compound in the presence of a catalyst, having the formula: where each of R1-R12 are independently H, alkyl, aryl, CF3, halogen, OR13, SO3R14, C(O)R15, CONR16R17 or CO2R18; each of R13-R18 is independently alkyl or aryl; and Z is alkl or aryl.
US08519130B2
Phosphorescent materials and devices with improved device manufacturing, fabrication, stability, efficiency, and/or color.
US08519127B2
Embodiments of this invention provide methods for therapeutic use of cyclic G-2-allylProline (cG-2-allylP) to treat peripheral neuropathies, including toxin-induced peripheral neuropathy and diabetic peripheral neuropathy as well as manufacture of medicaments including tablets, capsules, and other orally active compositions containing cG-2-allylP, as well as injectable solutions that are useful for treatment of such conditions.
US08519123B2
The present invention provides a compound of general formula 7, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine linked imidazo[1,5-a]pyridine conjugates attached through a piperazine moiety and different alkane spacers of general formula 7 wherein R represents H, OCH3, CF3, CN, F or Cl; n=3, 4, 5 or 6.
US08519121B2
Dextran for preparing medicine for anti-lung cancer, has repeated structure unit and molecular weight of 1.5-2.5 million Daltons. The dextran is extracted from land slug.
US08519118B2
Inhibition of RIP140 increases glucose transport. Compounds that inhibit RIP140 expression or activity are useful for treating disorders associated with aberrant glucose transport (e.g., diabetes), treating obesity, increasing metabolism (e.g., fatty acid metabolism), and increasing brown fat.
US08519115B2
The present invention relates to compositions and methods for detection and quantification of individual target molecules in biomolecular samples. In particular, the invention relates to improved, stable nanoreporter probes that are capable of binding to and identifying target molecules based on the probes' uniquely detectable signal. Methods for identifying target-specific sequences for inclusion in the probes are also provided, as are methods of making and using such probes. Polynucleotide sequences of certain nanoreporter components are also provided. The probes can be used in diagnostic, prognostic, quality control and screening applications.
US08519102B2
Conjugates of a Factor VIII moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising the conjugates, methods of making the conjugates, and methods of administering compositions comprising the conjugates to a patient.
US08519099B2
The current invention provides methods for producing a polypeptide as inclusion bodies in bacterial host cells. The present methods are carried out by forming a gene construct comprising the genetic sequence encoding a polypeptide operatively linked to that of an inclusion partner protein, such as E. coli thioredoxin or a modified E. coli thioredoxin, such that host cells comprising the gene construct produce the polypeptide as intracellular inclusion bodies. The methods of the present invention facilitate the rapid isolation and purification of recombinant proteins. In addition, the present methods may be useful for producing polypeptides or proteins which are small and are typically difficult to express, as well as those proteins that are toxic to host cells such as E. coli. The present invention also provides plasmids, vectors and host cells to be used in the present invention for production of polypeptides, and methods of production of polypeptides using these vectors and host cells. The invention further provides methods for producing protein molecular weight ladders for use in protein gel electrophoresis, as well as proteins and protein molecular weight ladders produced by these methods.
US08519097B2
The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.
US08519090B2
Embodiments of the invention are directed to yellow-to-transmissive conjugated polymers, a method to prepare the yellow conjugated polymers, the use of the yellow conjugated polymers in an electrochromic and/or electroluminescent device comprising neutral state primary subtractive colored conjugated polymers, and a method to prepare the device comprising the yellow conjugated polymer. The yellow conjugated polymers comprise a sequence of dioxythiophene units alternating with aromatic units, thiophene units, furan units, and/or pyrrole units. The yellow conjugated polymers are prepared by cross-condensation reactions. The yellow conjugated polymers can be soluble and preparation of the device involves deposition of the yellow conjugated polymer from solution onto a surface.
US08519089B2
Embodiments of the invention are directed to alternating donor-acceptor (DA) polymers that are soluble and display a blue or green neutral state that oxidizes to a transmissive state for use as an electrochromic polymer. The D units have 3,4-dioxythiophene, 3,6-dialkoxythieno[3,2-b]thiophene or 3,5-dialkoxy-dithieno[3,2-b:2′,3′-d]thiophene groups. Embodiments of the invention are directed to a method for preparation of the alternating DA polymeric sequences of the DA polymers by a cross-condensation of a nucleophilic acceptor monomer and an electrophilic donor monomer.
US08519087B2
Disclosed are a benzobis(thiadiazole)-based alternating copolymer, a method for preparing the same, and an organic electronic device including the same.The present disclosure provides a benzobis(thiadiazole)-based alternating copolymer represented by the chemical formula 1: wherein R1, R2 or R3 is hydrogen or C1-C20 linear, branched or cyclic alkyl, X is S, O, NR4, PR5, or HC═CH, wherein R4 or R5 is C1-C20 linear, branched or cyclic alkyl, Y is C, Si or N (in this case only one of R2 and R3 exists), and m is an integer from 1 to 3.
US08519082B2
A polycarbonate copolymer includes a repeating unit represented by a formula (1) below and a molar copolymer composition represented by Ar2/(Ar1+Ar2) in a range of 25 mol % to 50 mol %. In the formula (1): Ar1 and Ar2 represent a divalent aromatic group; a chain end is terminated by a monovalent aromatic group or a monovalent fluorine-containing aliphatic group; and n represents an average repeating number of an Ar1 block and is a numeral of 1.0 to 3.0, provided that Ar1 and Ar2 are not the same.
US08519079B2
A compound having a guanidine structure and uses thereof as organopolysiloxane polycondensation catalysts are described.
US08519077B2
N-type conjugated compounds are disclosed which include at least one conjugated electron-acceptor unit The conjugated electron-acceptor unit includes a diborylene unit. The compounds find application in an electron acceptor layer of an electronic device.
US08519076B2
A UV-crosslinkable polyacrylate pressure-sensitive adhesive composition having a polyacrylate having photoinitiator units incorporated therein by polymerization and being produced by a free-radical solvent-free polymerization process.
US08519073B2
A compound represented by general formula (I); and a polymeric compound including a structural unit (a1) represented by general formula (II). wherein R represents a hydrogen atom, a halogen atom, a lower alkyl group or a halogenated lower alkyl group; each of R1 to R3 independently represents an alkyl group or a fluorinated alkyl group, with the provision that no fluorine atom is bonded to a carbon atom adjacent to the tertiary carbon atom to which R1 to R3 are bonded, and at least one of R1 to R3 represents a fluorinated alkyl group; and R2 and R3 may form a ring structure.
US08519066B2
Embodiments include poly(allyl ether)s of polycyclopentadiene polyphenol that can be obtained by allylation of a polycyclopentadiene polyphenol, where the aromatic hydroxyl group(s) (—OH) are converted to HR1C═CR1—CH2—O— and/or H2R1C—CR1═HC—O—, where R1 is as described herein. Embodiments also include thermosettable compositions including the poly(allyl ether)s of polycyclopentadiene polyphenol and products obtained by curing the thermosettable compositions.
US08519059B2
The invention provides articles obtained from curing a composition consisting of a polymercapto crosslinking agent, a vulcanization accelerator, an inorganic base, a nitrogen containing chelating agent, wherein the nitrogen containing chelating agent is selected from the group consisting of 1,10-phenanthroline and 2,2-bipyridyl, and polyethylenimine; and a halogenated elastomer; wherein said nitrogen containing chelating agent is soluble in said halogenated elastomer.
US08519058B2
Novel, crosslinked polymers using biomass derived materials, such as aldaric acids and derivatives, are provided. The polymers can be used as hydrogels and in antimicrobial compositions.
US08519055B2
Disclosed are polyester resins and solvent borne thermosetting coating compositions that include these resins in combination with at least one crosslinker. The polyester resins contain 2,2,4,4-tetramethyl-1,3-cyclobutanediol and exhibit a combination of good solubility in organic solvents and high hardness with good flexibility in a coating composition.
US08519054B2
Thermoset polyolefin elastomer obtained by static curing with water a silane-grafted thermoplastic heterophasic polyolefin composition (I) having a flexural modulus equal to or lower than 150 MPa, and comprising: (a) a crystalline propylene homopolymer or copolymer of propylene with up to 15% by weight of ethylene or other alpha-olefin comonomer(s), or their combinations, and (b) a copolymer or a composition of copolymers of ethylene with other alpha-olefins containing from 15% by weight to less then 40% by weight of ethylene; said thermoset polyolefin elastomer having a compression set value of from 30 to 65%, a ratio of elongation at break to compression set values of above 8, and hardness shore A values below 90.
US08519051B2
The present invention provides a block copolymer for a drug conjugate which comprises a water-soluble polymer region consisting of polyethylene glycol and a polyamino acid region having a hydrazide group and a hydrophobic group in the side chain.
US08519041B2
The invention relates to absorptive, crosslinked polymeric composition that are based on partly neutralized, monoethylenically unsaturated monomer carrying acid groups wherein the absorptive crosslinked polymer may be coated with a polymeric coating, and have improved properties, in particular in respect of their capacity for transportation of liquids in the swollen state, and which have a high capacity and a high gel bed permeability.
US08519040B2
Disclosed are a novel ionic organic compound and a method for producing the ionic organic compound by a simple process. Also disclosed are a hydrogelling agent composed of an ionic organic compound obtained by the method, an alcohol gelling agent, a gel which uses the gelling agent, while using water or methanol as a medium, and a carbon nanotube dispersant composed of the compound. Specifically disclosed is an ionic organic compound represented by general formula (1). The compound is obtained by a condensation reaction of (A) an aromatic diamide compound or cyclohexane diamide compound having a 4-(chloromethyl)benzamide group at both ends, and (B) a compound selected from N,N,N′,N′-tetramethylalkylenediamines which may have a substituent wherein there are 1-6 carbon atoms between nitrogen atoms. The thus-obtained ionic organic compound serves as a gelling agent which is capable of gelling a neutral aqueous solution or an alcohol. The solvent solubility can be changed by substituting the anion of the thus-obtained ionic compound with another anion by anion-exchange. (In the formula, A represents a linking moiety having one or more optionally substituted aromatic rings or a linking moiety composed of a cyclohexane ring; B represents a cationic functional group having a quaternized nitrogen atom, which is selected from N,N,N′,N′-tetramethylalkylenediamines which may have a substituent wherein there are 1-6 carbon atoms between nitrogen atoms; X represents a monovalent anion; and n represents an integer of 1-800.)
US08519035B2
The present invention is related to the use of specific cyclic and/or polymeric aryl-phosphines as flame retardants and to a method for reducing the flammability of organic material by incorporating into the material these specific cyclic and/or polymeric phosphines. Moreover, the invention is related to a polymeric composition containing a polymeric material and at least one of the specific cyclic and/or polymeric phosphines in an amount of from 1 to 15% by weight, based on the weight of the polymeric material. The invention also relates to a composition comprising at least one of the specific cyclic and/or polymeric phosphines and at least one polymerizable monomer.
US08519034B2
The present invention is directed to the use of compound (A) and compound (B) in a polyethylene composition for increasing the lifetime of a pipe made of said polyethylene composition which is in permanent contact with chlorinated water, wherein compound (A) has the following formula (I): wherein—R6, R7 and R8 independently are non-substituted or substituted aliphatic or aromatic hydrocarbyl radicals which may comprise OH-groups, X1, X2, and X3 independently are H or OH, with the proviso that at least one of X1, X2, and X3 is OH, and the entire molecule does not comprise an ester group; wherein compound (B) has the following formula (II): wherein R1, R2, R3, R4 and R5 independently are H, or non-substituted or substituted aliphatic or aromatic hydrocarbyl radicals which may comprise heteroatoms, and wherein the base resin of said polyethylene composition consists of a polyethylene homo- or copolymer.
US08519030B2
The invention relates to a copolymer which is suitable as a superplasticizer for hydraulic binders and comprises 5 to 55 mol % of an isoprenol polyether derivative structural unit, 2 to 90 mol % of an acrylic acid derivative structural unit and 2 to 90 mol % of a hydroxyalkyl acrylate structural unit.
US08519029B2
A non-ionic polyether-polyester copolymer for extending workability to a cementitious mixture containing hydraulic cement and water, wherein the copolymer includes residues of at least the following monomers: Component A including an ethylenically unsaturated carboxylic acid ester monomer having a moiety hydrolysable in the cementitious mixture, wherein the hydrolyzed monomer residue has an active binding site for a component of the cementitious mixture; and, at least one of: Component B including an ethylenically unsaturated, carboxylic acid ester or alkenyl ether monomer having at least one C2-4 oxyalkylene side group of about 1 to 30 units; or, Component C including an ethylenically unsaturated, carboxylic acid ester or alkenyl ether monomer having at least one C2-4 oxyalkylene side group of 31 to about 350 units; wherein the molar ratio of Component A to the sum of the molar ratios of Component B and Component C is about 1:1 to about 10:1.
US08519023B2
The present invention concerns improved polymerizable anaerobic compositions which contain (meth)acrylic ester monomers, peroxy polymerization initiators, saccharin a saccharin derivative or a related sulfimide derivative and an activator containing a ferrocene moiety.
US08519018B2
A resin includes: an acrylate; and a curing agent to cure the acrylate. The resin is adapted to adhere to a degradable material selected from the group consisting of polylactic polymer (PLA), polyhydroxyalkonate (PHA), poly 3 hydroxybutrate co 3 hydroxyhexanote (PHBH), and paper. The curing agent includes a photoinitiator or a sensitizer that, when cured, form a hard coat when the resin is exposed to ultraviolet radiation or an electron beam.
US08519013B2
An object of the present invention is providing a method for producing formic acid under mild reaction conditions and by a simple procedure. As a means for achieving the object, the method for producing formic acid of the present invention is characterized by a reaction between carbon dioxide and hydrogen in the presence of an ionic liquid. According to the present invention, it is possible to generate formic acid effectively, because the method does not require that carbon dioxide be brought into a supercritical state and because no basic substances are required to be added to the reaction system.
US08519011B2
Disclosed is a process for converting synthesis gas to liquid hydrocarbon mixtures useful in the production of fuels and petrochemicals. The synthesis gas is contacted with at least two layers of synthesis gas conversion catalyst wherein each synthesis gas conversion catalyst layer is followed by a layer of hydrocracking catalyst and hydroisomerization catalyst or separate layers of hydrocracking and hydroisomerization catalysts. The process can occur within a single reactor, at an essentially common reactor temperature and an essentially common reactor pressure. The process provides a high yield of naphtha range liquid hydrocarbons and a low yield of wax.
US08519009B2
Disclosed are compositions that include treated biodiesel glycerin. The disclosed compositions may be utilized as soil-amendments for controlling pests, weeds and for enhancing growth of plants. The biodiesel glycerin utilized in the disclosed compositions may be treated by one or more steps including neutralization, heating, refluxing, condensing, and distilling.
US08519007B2
The present invention discloses certain diterpenes that can be used to inhibit androgen receptor activity, induce apoptosis and block cell cycle progression of androgen receptor-dependent cells. Androgen receptor has been associated with various diseases such as prostate cancer, androgeneic alopecia, breast cancer, acne etc. Accordingly, the present invention further discloses methods of treating androgen receptor-associated diseases by administering the disclosed diterpenes.
US08519003B2
The present invention relates to phenoxyphenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and also to a composition for this purpose, comprising the phenoxyphenylamidines according to the invention. Furthermore, the invention relates to a method for controlling unwanted microorganisms by applying the compounds according to the invention to the microorganisms and/or their habitat.
US08518997B2
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
US08518995B2
A method for a prevention and/or treatment of irritable bowel syndrome or amelioration of a symptom thereof in a subject, comprises administering to said subject an effective amount of a compound of formula I:
US08518992B2
The invention provides a method of synthesis of N-6-trimethyl-L-lysine (TML) derivative compounds for potential treatment of disorders resulting from deficiencies in the TML-carnitine pathway. The invention also provides a method of purification of TML and TML derivative compounds. The treatment of conditions of the diseases late infantile neuronal ceroid lipofuscinosis (LINCL) and neuronal ceroid lipofuscinosis (NCL) with TML were shown in the original parent application.
US08518990B2
A method for treating, preventing or ameliorating a hyperliferative disease and/or disorder in a mammal, comprises administering a therapeutically effective amount of one or more compounds selected from the group consisting of a compound of Formula (III), a compound of Formula (IV), and a pharmaceutically acceptable salt of Formula (III) or Formula (IV): wherein R2 is selected from the group consisting of methyl, ethyl, n-propyl, isopropyl, n-butyl, vinyl and allyl.
US08518988B2
Herein described is a novel crystalline form of the hydrochloride of the (4-hydroxycarbamoyl-phenyl)-carbamic acid (6-dimethylamino methyl-2-naphtalenyl) ester. In particular, herein described is a polymorph of the hydrochloride of the (4-hydroxycarbamoyl-phenyl)-carbamic acid (6-dimethylamino methyl-2-naphtalenyl) ester, characterized by a Powder X Ray Diffraction spectrum as indicated in FIG. 1, and/or by a DSC profile as indicated in FIG. 2, and/or by a TGA profile as indicated in FIG. 3 and/or by an IR spectrum as indicated in FIG. 4.
US08518985B2
The invention relates to novel compounds of the formula (I), in which W, X, Y, Z and CKE are each as defined above, to several methods and intermediates for preparation thereof and to the use thereof as pesticides and/or herbicides. The invention also relates to selective herbicidal compositions which comprise firstly haloalkylmethyleneoxyphenyl-substituted ketoenols and secondly a compound which improves crop plant compatibility.The present invention further relates to the enhancement of the action of crop protection compositions comprising especially haloalkylmethyleneoxyphenyl-substituted ketoenols, by the addition of ammonium or phosphonium salts and optionally penetration enhancers, to the corresponding compositions, to methods for production thereof and to the use thereof in crop protection as insecticides and/or acaricides and/or for preventing undesired plant growth.
US08518980B2
There are disclosed compound of Formula (1): A1, A2, A3 and A4 which may be the same or different, represent N or CR1, X is a divalent group selected from O, S(O)n, C═W, NR4, NC(═O)R5 and CR6R7, W is O, S, NR20, Y is N or CR8, one of R4, R5, R6, R8, R9 and NR20 represents -L-R3, in which L is a single bond or a linker group, additionally, R1, R3-R9, which may be the same or different, independently represent hydrogen or a substituent and R20 represents hydrogen, hydroxyl, alkyl optionally substituted by aryl, alkoxy optionally substituted by aryl, aryl, CN, optionally substituted alkoxy, optionally substituted aryloxy, optionally substitute alkanoyl, optionally substituted aroyl, NO2, NR30R31, in which R30 and R31, which may be the same or different, represent hydrogen, optionally substituted alkyl or optionally substituted aryl; additionally, one of R30 and R31 may represent optionally substituted alkanoyl or optionally substituted aroyl, n represents an integer from 0 to 2, in addition, when an adjacent pair of A1-A4 each represent CR1, then the adjacent carbon atoms, together with their substituents may form a ring B, when X is CR6R7, R6 and R7, together with the carbon atom to which they are attached may form a ring C, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the therapeutic and/or prophylactic treatment of Duchenne muscular dystrophy, Becker muscular dystrophy or cachexia.
US08518975B2
This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formula (I).
US08518973B2
A compound having the following formula [I] or a pharmaceutically acceptable salt thereof: wherein A is an aromatic five-membered heterocycle which optionally is fused with a cycloalkane ring; B is an alkylene; R1 and R2 are hydrogen, hydroxyl, alkoxy, aryloxy, alkyl, cycloalkyl, aryl, heterocycle, amino, alkylamino, arylamino or acyl, or R1 and R2 join together to form a heterocycle; X and Y are hydrogen, halogen, hydroxyl, alkoxy, aryloxy, alkyl, cycloalkyl, aryl, mercapto, alkylthio, arylthio, carboxyl, an ester of carboxyl, an amide of carboxyl, cyano or nitro; p is 0, 1 or 2; and q is 0 or 1. The compound is useful for treating diseases in which angiogenesis or augmentation of vascular permeability is involved.
US08518971B2
A compound of formula (I): wherein A, p, R1, R3, R4, R5, R6, m, R7, n and R8 are as defined in claim 1. Furthermore, the present invention relates to intermediates used to prepare compounds of formula (I), to methods of using them to combat and control insect, acarine, nematode and mollusc pests and to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising them.
US08518953B2
The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.
US08518951B2
Described herein are 4-methyl-piperazine-1-carbothioic acid amide derivatives and analogs, as well as compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by hemorrhagic fever viruses, such as Arenaviruses.
US08518949B2
Crystalline polymorphous forms of the rifaximin (INN) antibiotic named rifaximin δ and rifaximin ε useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
US08518946B2
Pharmaceutically acceptable salts of (R)-7-[3-amino-4-(2,4,5-trifluorophenyl)-butyryl]-3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-formic acid, their preparation methods, compositions containing the said pharmaceutical salts and their use as medicaments, especially as dipeptidyl peptidase IV (DPP-IV) inhibitors are disclosed. Of the many acceptable salts, one example is the following.
US08518943B2
The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
US08518940B2
The present invention embraces compounds selected for interacting with the Fingers-Palm pocket of telomerase and use thereof for modulating the activity of telomerase and preventing or treating diseases or conditions associated with telomerase.
US08518922B2
The invention provides and describes solid state 17α-ethynyl-5α-androstane-3α,17β-diol including amorphous and crystalline forms and specific polymorphic forms thereof. Anhydrates and solvates of 17α-ethynyl-5α-androstane-3α,17β-diol include Form III anhydrate and Form I solvate. The invention further relates to solid and suspension formulations containing 17α-ethynyl-5α-androstane-3α,17β-diol in a described solid state form and use of the formulations to treat cancers or precancers such as prostate cancer or breast cancer in subjects or human patients. The invention also relates to methods to make liquid formulations from solid state forms of 17α-ethynyl-5α-androstane-3α,17β-diol and uses of such formulations in treating the described conditions.
US08518921B2
Compositions useful for inducing bone growth or inhibiting bone loss in an animal comprising one or more isoflavones or isoflavone metabolites and methods for inducing bone growth or inhibiting bone loss in an animal utilizing such compositions. The compositions and methods are particularly useful for post-menopause, post-andropause, gonadectomized, spayed, or neutered animals.
US08518919B2
The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions into the oral cavity, upon intranasal or ocular administration of the compositions. Especially effective excipients used in the compositions of the present invention are hypromellose as a viscosity modifier and sucralose as a taste-masking agent. The invention also provides methods of treating or preventing certain disorders, or symptomatic relief therefrom, by administering the compositions of the invention to a patient, e.g., for the symptomatic relief of allergic rhinitis, non-allergic vasomotor rhinitis, allergic conjunctivitis, as well as other disorders.
US08518911B2
The invention encompasses pyrazolo[1,5-a]pyridine derivatives which selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease. Pharmaceutical compositions and methods of use are also included.
US08518907B2
The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of CTNNB1 gene expression and/or activity, and/or modulate a beta-catenin gene expression pathway. Specifically, the invention relates to double-stranded nucleic acid molecules including small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules that are capable of mediating or that mediate RNA interference (RNAi) against CTNNB1 gene expression.
US08518905B2
The present invention relates to the use of a TLR9 agonist and/or a TLR4 antagonist and/or a NOD2 agonist for treatment or prevention of disorders involving TLR4 activation, such as systemic sepsis and necrotizing enterocolitis.
US08518900B2
Described are methods for making macrolides, and, in particular, a method for making optionally substituted 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide and derivatives thereof, as well as uses of macrolides to make medicaments, methods of treatment using macrolides, and methods for making intermediates that, among other uses, may be used to make macrolides. Also described are solvated and non-solvated crystalline forms of 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from) such crystalline forms, methods for making medicaments comprising (or derived from) such crystalline forms, methods of treatment using such crystalline forms, and kits comprising such crystalline forms.
US08518886B2
The present invention relates generally to the use of γ-glutamyl antioxidants, particularly γ-glutamyl-cysteine, as cytoprotective agents to prevent reperfusion injury (i.e., hemorrhagic transformation) of the blood-brain barrier during reperfusion following an ischemic stroke. The γ-glutamyl antioxidants can be used alone or used in combination with an agent which inhibits the reverse movement of Na/Ca exchange in the blood-brain barrier such as 2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea methanesulphonate (KB-R7943).
US08518885B2
A novel class of peptide α-ketoamides useful for selectively inhibiting calpains, selectively inhibiting cysteine proteases, and generally inhibiting all cysteine proteases, having the formula M-AA2-AA1-CO—NH—(CH2)n—R3. Processes for the synthesis of peptidyl α-ketoamide derivatives. Compositions and methods for inhibiting cysteine proteases, inhibiting calpains, and treating disease caused by cysteine proteases and calpains are provided.
US08518879B2
The present invention relates to skin care compositions, including cosmeceuticals, for topical application, and more particularly, a skin cream, comprising cell culture medium conditioned by cells grown in two-dimensional culture. Also included are methods of using such compositions and kits comprising the skin cream therein.
US08518876B2
The invention describes compositions of peptide analogs that are active in blood or cleavable in blood to release an active peptide. The peptide analogs have a general formula: A-(Cm)x-Peptide (SEQ ID NO: 76), wherein A is hydrophobic moiety or a metal binding moiety, e.g., a chemical group or moiety containing 1) an alkyl group having 6 to 36 carbon units, 2) a nitrilotriacetic acid group, 3) an imidodiacetic acid group, or 4) a moiety of formula (ZyHisw)p (SEQ ID NO: 50), wherein Z is any amino acid residue other than histidine, His is histidine, y is an integer from 0-6; w is an integer from 1-6; and p is an integer from 1-6; wherein if A has alkyl group with 6 to 36 carbon units x is greater than 0; and Cm is a cleavable moiety consisting of glycine or alanine or lysine or arginine or N-Arginine or N-lysine, wherein x is an integer between 0-6 and N may be any amino acid or none. The peptide analogs are complexed with polymeric carrier to provide enhanced half-life.
US08518873B2
Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of C. difficile and C. difficile spores. Methods for the treatment, prophylaxis and prevention of C. difficile infection and disease in animals, including humans, are described.
US08518871B2
The present disclosure provides peptides and peptide compositions, which facilitate the delivery of an active agent or an active agent carrier wherein the compositions are capable of penetrating the stratum corneum (SC) and/or the cellular membranes of viable cells.
US08518867B2
The invention relates to a solid, textile or skin care composition which comprises a water-soluble carrier, a textile-softening clay and a textile or skin care compound. The invention especially relates to a solid, textile or skin care composition wherein the water-soluble carrier is particulate and is coated with a powder comprising the softening clay and the textile or skin care compound. The invention also relates to textile-softening detergents or cleaning agents which comprise the textile or skin care composition.
US08518864B2
A grease composition for constant-velocity joints which is inexpensive and which and which has an improved anti-flaking property without using materials which have environmental burdens, and a constant-velocity joint enclosing this grease are provided. A grease composition for constant-velocity joints comprising:(a) a base oil,(b) a diurea thickener,(c) a zinc dialkyldithiophosphate,(d) a sulfurized molybdenum dialkyldithiocarbamate,(e) a zinc dialkyldithiocarbamate, and(f) a sulfur-nitrogen extreme pressure additiveis provided.
US08518861B2
A solid zirconium cross-linking agent and use in a cross-linking composition in oil field applications such as hydraulic fracturing and plugging of permeable zones. The zirconium cross-linking agent is prepared by a process comprising contacting a zirconium complex with an alkanolamine and water at particular mole ratios of alkanolamine and water to zirconium.
US08518854B2
Heterogeneous catalyst systems, methods of making these systems, and methods of using these systems, wherein catalytically active gold is deposited onto composite support media. The composite support media is formed by providing nanoporous material on at least a portion of the surfaces of carbonaceous host material. In representative embodiments, relatively fine, nanoporous guest particles are coated or otherwise provided on surfaces of relatively coarser activated carbon particles. Catalytically active gold may be deposited onto one or both of the guest or host materials either before or after the guest and host materials are combined to from the composite host material. PVD is the preferred catalyst system of depositing gold.
US08518843B2
To provide a heat-absorbing glass plate which comprises soda lime silica glass containing coloring components, the coloring components containing, as represented by mass % based on the following oxides, from 0.45 to 0.61% of total iron as calculated as Fe2O3 and from 0.2 to 0.6% of TiO2, which contains substantially no CoO, Cr2O3, V2O5, MnO nor CeO2, which has a mass proportion of bivalent iron as calculated as Fe2O3 in total iron as calculated as Fe2O3 of from 45 to 60%, which has a solar transmittance of at most 42% calculated as 4 mm thickness, which has a visible light transmittance (by illuminant A) of at least 70% calculated as 4 mm thickness, and which provides a transmitted light having a dominant wavelength of from 492 to 500 nm.
US08518840B2
A synthetic resin leather has a substrate and a synthetic resin layer attached to the substrate. The substrate is a both sides cross-knitted fabric and is prepared by cross-knitting a first yarn with 10 to 40 in count including single spun or mixed spun fibers made of rayon, cotton, polyester, nylon, acryl, or urethane and a second yarn with 50 to 300 in denier including crimpy long fiber filaments, thermoplastic elastomer long fiber filaments or polyurethane long fiber filaments; and knitting the both-sided cross-knitted fabric so loops made of the first yarn and loops made of the second yarn are formed on the front and rear sides of the substrate and are in alternating positions on the front side as compared to the rear side; and, on each side of the substrate, loops of the first and second yarns are formed in alternating positions in longitudinal and transverse directions.
US08518839B2
The invention relates to a rolled product having a thickness that can be adjusted by means of separation. The inventive product comprises an alternating stack (2) of sheets (4) and layers (6) of an adhesive material (8). Each of said sheets (4) has an intrinsic resistance to tearing and each layer (6) of adhesive material (8) joins together two adjacent sheets (4) in the stack (2) using a bond strength that is lower than the tearing resistance of the sheets (4). In this way, each sheet (4) can be detached from the stack (2) without being torn. According to the invention, each sheet (4) is essentially made from woven fibers and each sheet (4) belonging to each pair of sheets (4) which are adjacent to the same layer (6) of adhesive material (8) is impregnated, throughout the thickness thereof, with a mass of adhesive material (8) which is incorporated in the shared layer (6) of adhesive material (8).
US08518836B1
One or more techniques or systems for forming a pattern during semiconductor fabrication are provided herein. In some embodiments, a photo resist (PR) region is patterned and a spacer region is formed above or surrounding at least a portion of the patterned PR region. Additionally, at least some of the spacer region and the patterned PR region are removed to form one or more spacers. Additionally, a block co-polymer (BCP) is filled between the spacers. In some embodiments, the BCP comprises a first polymer and a second polymer. In some embodiments, the second polymer is removed, thus forming a pattern comprising the first polymer and the spacers. In this manner, a method for forming a pattern during semiconductor fabrication is provided, such that a width of the spacer or the first polymer is controlled.
US08518834B2
A method for forming an oxide film on a carbon film includes the steps of forming a carbon film on an object to be processed; forming an object-to-be-oxidized layer on the carbon film; and forming an oxide film on the object-to-be-oxidized layer while oxidizing the object-to-be-oxidized layer.
US08518831B2
A method of forming semiconductor memory device includes forming first to fourth spacers over a target layer including a first region and second regions adjacent to the first region so that a first spacer group including the first spacers spaced at a first interval is formed in the first region of the target layer, a second spacer group including the second spacers spaced at second intervals is formed in the second regions, a third spacer is formed between the first and the second spacer groups, and fourth spacers are formed between the third spacer and the first spacer group; forming an overlap pattern blocking the target layer; and forming first patterns, spaced at the first interval and each formed to have a first width, in the first region and second patterns, spaced at the second intervals and each formed to have a second width, in the second regions.
US08518830B2
Disclosed is a plasma etching method capable of carrying out an etching process while preventing an etching shape defect such as a bowing from occurring. The plasma etching method includes etching an organic film formed on the substrate to a middle depth using an inorganic film as a mask by generating plasma between an upper electrode a surface of which is formed with a silicon containing material and a lower electrode where a substrate to be processed is placed thereon in a processing chamber; forming a protective film including the silicon containing material of the upper electrode on a side wall of an etching region formed from the etching process by applying a negative DC voltage on the upper electrode while generating the plasma; and continuing the etching process using the plasma thereby etching the organic film to a predetermined depth.
US08518828B2
According to a disclosed semiconductor device fabrication method according to one embodiment of the present invention, a layer having a line-and-space pattern extending in one direction is etched using another layer having a line-and-space pattern extending in another direction intersecting the one direction, thereby obtaining a mask having two-dimensionally arranged dots. An underlying layer is etched using the mask, thereby providing two-dimensionally arranged pillars.
US08518826B2
One aspect of the present invention is a method of processing a substrate. In one embodiment, the method comprises forming an electrical conductor on or in the substrate by providing a mixture comprising metal particles and an electroless deposition solution and electrolessly depositing a metal matrix and co-depositing the metal particles. In another embodiment, the method comprises forming an electrical conductor on or in the substrate by providing a mixture comprising metal particles and an electrochemical plating solution and electrochemically plating a metal matrix and co-depositing the metal particles. Another aspect of the present invention is a mixture for the formation of an electrical conductor on or in a substrate. Another aspect of the present invention is an electronic device.
US08518823B2
The present invention relates to a through silicon via (TSV). The TSV is disposed in a substrate including a via opening penetrating through a first surface and a second surface of the substrate. The TSV includes an insulation layer, a barrier layer, a buffer layer and a conductive electrode. The insulation layer is disposed on the surface of the via opening. The barrier layer is disposed on the surface of the insulation layer. The conductive electrode is disposed on the surface of the buffer layer and fills the via opening. The buffer layer further covers a surface of the conductive electrode at the side of the second surface. The present invention further discloses a method of forming the TSV.
US08518819B2
A semiconductor contact structure and method provide contact structures that extend through a dielectric material and provide contact to multiple different subjacent materials including a silicide material and a non-silicide material such as doped silicon. The contact structures includes a lower composite layer formed using a multi-step ionized metal plasma (IMP) deposition operation. A lower IMP film is formed at a high AC bias power followed by the formation of an upper IMP film at a lower AC bias power. The composite layer may be formed of titanium. A further layer is formed as a liner over the composite layer and the liner layer may advantageously be formed using CVD and may be TiN. A conductive plug material such as tungsten or copper fills the contact openings.
US08518814B2
A method of fabricating a high-density laser diode stack is disclosed. The laser diode bars each have an emitter surface and opposing surfaces on either side of the emitter surface. Each laser diode bar has metallization layers on the opposing surfaces and a solder layer on at least one of the metallization layers. The solder layer is applied to a semiconductor wafer prior to cleaving the wafer to create the laser diode bars. The laser diode bars are arranged in a stack such that the emitter surfaces of the bars are facing the same direction. The stack of laser diode bars is placed in a vacuum chamber. An anti-reflection coating is deposited on the emitter surfaces of the laser diode bars in the chamber. The laser diode bars are joined by applying a temperature sufficient to reflow the solder layers in the chamber.
US08518812B2
Some embodiments include methods of forming contacts. A row of projections may be formed over a semiconductor substrate. The projections may include a plurality of repeating components of an array, and a terminal projection. The terminal projection may have a sacrificial material spaced from semiconductor material of the substrate by a dielectric structure. An electrically conductive line may be formed along the row. The line may wrap around an end of the terminal projection and bifurcate into two branches that are along opposing sides of the repeating components. The individual branches may have regions spaced from the sacrificial material by segments of gate dielectric. The sacrificial material may be removed, together with the segments of gate dielectric, to form a contact opening. An electrically conductive contact may be formed within the contact opening and directly against the regions of the branches.
US08518811B2
In one embodiment, the semiconductor device includes a first doped region disposed in a first region of a substrate. A first metal electrode having a first portion of a metal layer is disposed over and contacts the first doped region. A second doped region is disposed in a second region of the substrate. A dielectric layer is disposed on the second doped region. A second metal electrode having a second portion of the metal layer is disposed over the dielectric layer. The second metal electrode is capacitively coupled to the second doped region.
US08518808B2
A GaN sample in a sealed enclosure is heated very fast to a high temperature above the point where GaN is thermodynamically stable and is then cooled down very fast to a temperature where it is thermodynamically stable. The time of the GaN exposure to a high temperature range above its thermodynamic stability is sufficiently short, in a range of few seconds, to prevent the GaN from decomposing. This heating and cooling cycle is repeated multiple times without removing the sample from the enclosure. As a result, by accumulating the exposure time in each cycle, the GaN sample can be exposed to a high temperature above its point of thermodynamic stability for a long time but the GaN sample integrity is maintained (i.e., the GaN doesn't decompose) due to the extremely short heating duration of each single cycle.
US08518798B2
One or more embodiments relate to a method for forming a semiconductor structure, including: forming a semiconductor layer; and forming a dielectric layer over a back side of said semiconductor layer. In one or more embodiments, the dielectric layer may be a silicone rubber layer.
US08518795B2
A method of manufacturing a semiconductor device includes forming an isolation region defining an active region in a semiconductor substrate, forming a first insulating film over the semiconductor substrate, forming a second insulating film having etching properties different from those of the first insulating film over the first insulating film, selectively removing the second insulating film from a first region over the active region and the isolation region by dry etching using a fluorocarbon-based etching gas, removing a residual film formed by the dry etching over the first insulating film by exposure in an atmosphere containing oxygen, and selectively removing the first insulating film from the first region by wet etching.
US08518783B2
A field effect transistor having a gate structure that comprises an interfacial layer positioned in between the transistor channel region and a high-K dielectric layer of the gate stack. The interfacial layer comprises AlxSiyOz, which has a higher relative dielectric constant value than SiO2. A method of forming the gate structure of a field effect transistor. The method includes forming a gate stack comprising, in order: a SiO2-based layer adjacent a channel region of the field effect transistor; a high-K dielectric layer on the SiO2-based layer; and a gate electrode on the high-K dielectric layer. The method also includes introducing Al into the SiO2-based layer to form an AlxSiyOz interfacial layer in between the high-K dielectric layer and the channel region. A heating step to allows Al introduced into channel region to diffuse out of the channel region into the interfacial layer.
US08518772B2
A fabricating method of a semiconductor device includes forming an interlayer insulation layer on a substrate, the interlayer insulation layer including a storage node contact plug, forming an etch stop layer on the interlayer insulation layer, the etch stop layer including a silicon layer or a silicon germanium layer, forming a molding insulation layer on the etch stop layer, forming a hole in the molding insulation layer by selectively etching the molding insulation layer until a portion of the etch stop layer is exposed, forming a first conductive layer conformally on an inner surface of the hole and on a top surface of the molding insulation layer, and forming a metal silicide pattern in a predetermined area of the etch stop layer exposed by the molding insulation layer by annealing the first conductive layer and the etch stop layer.
US08518771B2
A method is provided for manufacturing a solid-state imaging device including a semiconductor substrate having a photoelectric conversion portion, a pixel transistor region and a logic circuit region. The method includes the steps of forming a first gate electrode on the semiconductor substrate with a first gate insulating film therebetween, a second gate electrode in the pixel transistor region on the semiconductor substrate with a second gate insulating film therebetween; forming a first insulating layer to cover the first gate electrode, the second gate electrode, a floating diffusion region where a floating diffusion portion is to be formed, and the photoelectric conversion portion; and forming an offset spacer on a sidewall of the first gate electrode by etch back of the first insulating layer in a state where the photoelectric conversion portion, the pixel transistor region and the floating diffusion region are masked.
US08518766B2
A field effect transistor (FET) includes a body region and a source region disposed at least partially in the body region. The FET also includes a drain region disposed at least partially in the body region and a molybdenum oxynitride (MoNO) gate. The FET also includes a dielectric having a high dielectric constant (k) disposed between the body region and the MoNO gate.
US08518759B2
A method for fabricating a field-effect transistor is provided. The method includes forming a substrate region, forming two terminal regions at the substrate region, one terminal region being a source region and the other terminal region being a drain region, forming two electrically insulating insulating layers, which are arranged at mutually opposite sides of the substrate region and are adjoined by control regions, forming an electrically conductive connecting region, which electrically conductively connects one of the terminal regions and the substrate region the conductive connecting region comprising a metal-semiconductor compound, leveling a surface by chemical mechanical polishing after forming the control regions, etching-back the control regions after polishing, and performing a self-aligning method for forming the metal-semiconductor compound in the etched-back regions, on the substrate region, and on a terminal region.
US08518751B2
A method of manufacturing a semiconductor device comprises: preparing a lead frame including a package external region and a package internal region, a burred surface being provided at a top end of a side of the lead frame, and a fracture surface being provided in the vicinity of the top end of the side; chamfering the top end of the side in the package external region; mounting a semiconductor element on the lead frame and sealing the semiconductor element with mold resin in the package internal region; and removing resin burr provided on the side of the lead frame in the package external region after the chamfering and the sealing.
US08518745B2
A method of manufacturing a semiconductor device is provided. The method includes the steps of pasting a film for forming a protective layer in which a support base, an adhesive layer, and a thermosetting resin layer are laminated, in that order, onto a bumped wafer in which a low dielectric material layer is formed, with the thermosetting resin layer serving as a pasting surface, and further, peeling the support base and the adhesive layer from the thermosetting resin layer, forming a protective layer by thermally curing the thermosetting resin layer, and dicing the bumped wafer and the protective layer together.
US08518743B2
A die structure and a die connecting method using the same are provided. The die structure includes a die and a bump structure. The bump structure includes a body and a solder layer. The body is disposed on the die. The solder layer is disposed on the body. The method includes providing a die structure mentioned above, providing a circuit board mentioned above, and soldering the solder layer of the die structure with the tine layer on the copper block of the circuit board. In different embodiments, a tin layer is omitted from the circuit board, wherein the solder layer of the die structure is directly soldered onto the surface of the copper block.
US08518741B1
A method for fabricating a multi-chip stacked structure includes joining multiple wafers with interconnect structures interposed between each set of adjacent wafers. As each wafer is added to the stack, the new wafer is thinned to expose a through silicon via and back side metallization is performed. After the last wafer has been so joined, the wafer stack is diced and then joined to a substrate with a final interconnect structure interposed between the final wafer and the substrate.
US08518733B2
Provided is a method of manufacturing an electromechanical transducer having a reduced variation in a breakdown strength caused by a variation in flatness of an insulating layer. In the method of manufacturing the electromechanical transducer, a first insulating layer is formed on a first substrate, a barrier wall is formed by removing a part of the first insulating layer, and a second insulating layer is formed on a region of the first substrate after the part of the first insulating layer has been removed. Next, a gap is formed by bonding a second substrate on the barrier wall, and a vibration film that is opposed to the second insulating layer via the gap is formed from the second substrate. In the forming of the barrier wall, a height on a gap side in a direction vertical to the first substrate becomes lower than a height of a center portion.
US08518730B2
A sapphire wafer dividing method including a cut groove forming step of forming a plurality of cut grooves on the back side of a sapphire wafer along a plurality of crossing division lines formed on the front side where a light emitting layer is formed, a modified layer forming step of forming a plurality of modified layers inside the sapphire wafer along the division lines, and a dividing step of dividing the sapphire wafer into individual light emitting devices along the modified layers as a division start point, thereby chamfering the corners of the back side of each light emitting device owing to the formation of the cut grooves in the cut groove forming step.
US08518728B2
In case that a conventional TFT is formed to have an inversely staggered type, a resist mask is required to be formed by an exposing, developing, and droplet discharging in forming an island-like semiconductor region. It resulted in the increase in the number of processes and the number of materials. According to the present invention, a process can be simplified since after forming a source region and a drain region, a portion serving as a channel region is covered by an insulating film serving as a channel protecting film to form an island-like semiconductor film, and so a semiconductor element can be manufactured by using only metal mask without using a resist mask.
US08518727B2
An organic light emitting diode (OLED) display device and method of fabrication that includes a substrate having a device region, an outer dam region and an encapsulation region. The encapsulation region includes an inner dam region, an outer dam region and an encapsulation region that correspond to the device region. An encapsulation agent is formed in the encapsulation region of the encapsulation substrate, and filling dams are formed of the same material in the outer dam region and the inner dam region of the encapsulation substrate.
US08518725B2
A method for processing a silicon substrate includes providing a combination of a first silicon substrate, a second silicon substrate, and an intermediate layer including a plurality of recessed portions, which is provided between the first silicon substrate and the second silicon substrate, forming a first through hole that goes through the first silicon substrate by executing etching of the first silicon substrate on a surface of the first silicon substrate opposite to a bonding surface with the intermediate layer by using a first mask, and exposing a portion of the intermediate layer corresponding to the plurality of recessed portions of the intermediate layer, forming a plurality of openings on the intermediate layer by removing a portion constituting a bottom of the plurality of recessed portions, and forming a second through hole that goes through the second silicon substrate by executing second etching of the second silicon substrate by using the intermediate layer on which the plurality of openings are formed as a mask.
US08518723B2
A method of fabricating a semiconductor integrated circuit device, including providing a semiconductor substrate, sequentially forming an etching target layer and a hard mask layer on the semiconductor substrate, forming first etch masks on the hard mask layer, the first etch masks including a plurality of first line patterns spaced apart from one another at a first pitch and extending in a first direction, forming first hard mask patterns by etching the hard mask layer using the first etch masks, forming second etch masks on the first hard mask patterns, the second etch masks including a plurality of second line patterns spaced apart from one another at a second pitch and extending in a second direction different from the first direction, forming second hard mask patterns by etching the first hard mask patterns using the second etch masks, forming spacers on sidewalls of the second hard mask patterns, and patterning the etching target layer using the second hard mask patterns having the spacers.
US08518713B2
Generally, conjugate systems, self-illuminating quantum dot conjugates, methods of detecting a target in a host, methods of treating a disease in a host, and the like, are described herein.
US08518705B2
The present invention provides structures and methods that allow polymers of any length, including nucleic acids containing entire genomes, to be stretched into a long, linear conformation for further analysis. The present invention also provides structures and methods for selecting and stretching polymers based on their lengths. Polymers are loaded into a device and run through the structures. Stretching is achieved by, e.g., applying shear forces as the polymer passes through the structures, placing obstacles in the path of the polymer, or a combination thereof. Since multiple molecules may be stretched in succession, extremely high throughput screening, e.g., screening of more than one molecule per second, is achieved.
US08518704B2
A monitoring system is presented. The monitoring system may include a first chemical vessel containing a first chemical mixture and a second chemical vessel containing a second chemical mixture. The monitoring system may further include a sensor configured to selectively receive a first sample flow of the first chemical mixture from the first chemical vessel and a second sample flow of the second chemical mixture from the second chemical vessel. The sensor may be configured to measure a first sample attribute value of the first sample flow and a second sample attribute value of the second sample flow. By multiplexing multiple sample flows through a sensor, the monitoring system may monitor attributes of multiple chemical mixtures without requiring separate sensors for each chemical mixture monitored by the system.In an embodiment, the monitoring system is preferably configured to control an attribute of a chemical mixture. In such a case, the monitoring system may further include a control system configured to receive the first sample attribute value and the second sample attribute value from the sensor. The control system is further preferably configured to input the first sample attribute value into a first attribute control algorithm to calculate a first attribute control output. The first chemical mixture includes a first bulk attribute value, and the control system is preferably configured to direct the adjusting of the first bulk attribute value.
US08518698B1
The invention provides a method of promoting apoptosis of human glioblastoma multiforme (GBM) tumor cells. The method comprises isolating GBM tumor cells from a human brain biopsy specimen, isolating human neural stem cells (HNSCs) from the biopsy specimen, transforming the isolated HNSCs with an operative PEX gene, and exposing GBM tumor cells to the transformed HNSCs to thereby promote apoptosis of the tumor cells mediated by the expressed PEX gene.
US08518682B2
A tissue engineering composition adapted for application to an interior surface of a body lumen of a patient. The composition comprises (a) a carrier medium that is adapted to flow and to stably adhere the composition to the body lumen and (b) microcapsules, which are dispersed within the carrier medium and which contain one or more living cells encapsulated within a coating that includes a biodegradable polymer. The composition promotes growth of the cells on the lumen surface subsequent to application of the composition to the lumen.
US08518676B2
The present invention relates to isolated polypeptides having C4-dicarboxylic acid transporter activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, and methods of producing C4-dicarboxylic acids, such as malic acid.
US08518673B2
The present disclosure includes a method for processing a beer stream for the recovery of oil. The method includes a step of extracting oil from a beer stream into an organic phase comprising an organic solvent to provide in the organic phase at least a portion of the oil. In general, a beer stream refers to a composition containing alcohol, water, oil, and particulates, and can be a result of a fermentation process. The beer stream can contain other components commonly found in a stream coming off a fermentation process such as, for example, glycerol and acetic acid.
US08518669B2
An object is to provide a means of highly producing an oxalate decarboxylase originating in a microorganism. A recombinant expression plasmid vector, which contains an α-amylase promoter belonging to the genus Bacillus and an oxalate decarboxylase gene originating in a microorganism that is provided under the control of the promoter, is constructed. A host bacterium is transformed with this vector to prepare an oxalate decarboxylase producing bacterium. A recombinant oxalate decarboxylase is produced by culturing the producing bacterium and then recovering the oxalate decarboxylase thus produced.
US08518664B2
Methods of determining the amount of microorganisms present in a test sample. The methods include a) incubating the test sample with a growth media to form an incubated sample, wherein the growth media includes an enzyme substrate and the enzyme substrate includes an enzymatically hydrolyzable group and a fluorescent group, wherein microorganisms present in the test sample include an enzyme that hydrolyzes the hydrolyzable group from the fluorescent group to form a fluorescently detectable product, wherein the fluorescently detectable product has both an acidic and basic species; b) exciting the fluorescently detectable product with light having a wavelength of Exλiso for a time sufficient for the fluorescently detectable product to emit light, wherein Exλiso is the absorbance isosbestic point of the fluorescently detectable product; c) detecting light emitted at a wavelength of Emλ1; and d) quantifying the light emitted at the wavelength of Emλ1, wherein the quantity of the light emitted at the wavelength Emλ1 is indicative of the amount of microorganisms present in the test sample.
US08518663B2
In various embodiments, the invention relates to a method for identifying the presence of particular bacteria in a sample. The method includes collecting a sample that includes or has been exposed to the particular bacteria and detecting, in the sample, at least one volatile organic compound indicative of the presence of the bacteria.
US08518659B2
The present invention relates to a method for determining the degree of risk of onset of autism, comprising the step of measuring the triglyceride concentration or the cholesterol concentration in a very low-density lipoprotein fraction of plasma or serum isolated from a subject, or the triglyceride concentration or the cholesterol concentration of plasma or serum. In addition, the present invention provides a kit for determining the degree of risk of onset of autism and a method for screening for a candidate substance for agents for treating autism using a non-human mammal, in which the above described method is utilized.
US08518658B1
Disclosed is a method and associated device for the rapid identification of viable bacterial contaminants in food products. The method detects viable microbes by using a combined ATP-bioluminescence immunoassay. Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium were selected as target organisms in various matrices including ground beef homogenate, apple juice, milk, and phosphate-buffered saline. Specific antibodies were immobilized on the surface of well plates in which the sample matrices were incubated. The plates were washed, and the wells were incubated with BacTiter-Glo reagent in Mueller-Hinton II broth. Bioluminescent output was measured with a luminometer and signal-to-noise ratios were calculated. The LOD was not affected by the presence of non-target cells. A strong linear correlation was observed between the number of cells and luminescent output over 4 orders of magnitude. This method provides a means of simultaneously detecting and identifying viable pathogens in complex matrices.
US08518657B2
A method for diagnosing the presence of hereditary spastic paraplegia (HSP) or predicting the risk of developing HSP in a human subject, comprising detecting the presence or absence of a defect in a gene encoding a polypeptide comprising the sequence of FIG. 9 (SEQ ID NO: 19), in a nucleic acid sample of the subject, whereby the detection of the defect is indicative that the subject has or is at risk of developing HSP.
US08518652B2
Methods/reagents for detecting and/or treating cancers or potential cancers are disclosed. In one embodiment, methods and reagents for detecting truncated forms of P2X7 protein in cells are described. In one embodiment, methods and reagents for increasing the amount and/or activity of full-length P2X7 in cells are described. In one embodiment, methods and reagents for decreasing the amount and/or activity of truncated P2X7 in cells are described.
US08518649B2
This invention is in the field of homeostasis analysis. More particularly, it relates to systems and methods for analyzing persistent homeostatic perturbations, i.e. chronic stress, by measuring levels of biomarkers that are related to chronic stress. This invention is also directed to systems and methods for analyzing the molecular mechanisms of chronic stress.
US08518648B2
It has been demonstrated that the level of HBP increases in individuals that subsequently develop severe sepsis. Accordingly, the level of HBP, HBP/WBC ratio or HBP/NC ratio in an individual can be used to determine whether or not an individual is at risk of developing severe sepsis.
US08518647B2
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon (including colon adenocarcinoma) cancer patients, wherein the methods related to measuring miR levels can predict poor survival. The invention also provides methods of identifying inhibitors of tumorigenesis.
US08518641B2
The invention relates to a method of for detecting DNA damage in a tissue sample. The method includes the steps of exposing sample DNA to a tagged DNA-damage binding factor and then shearing the DNA to produce fragments. After separating damaged from undamaged DNA, the two are amplified and differentially labeled. The labeled fragments can be immobilized on a microarray allowing the location and extent of any DNA damage to be determined.
US08518632B2
In a method of manufacturing an electroforming mold, a first photoresist layer is formed on an upper surface of a bottom conductive film of a substrate, and the first photoresist layer is divided into a first soluble portion and a first insoluble portion. A conductive material is thermally deposited on an upper surface of the first photoresist layer within a predetermined temperature range, to thereby form an intermediate conductive film. An intermediate conductive film is patterned. A second photoresist layer is formed on an exposed upper surface of the first photoresist layer after the intermediate conductive film is removed, and on an upper surface of the intermediate conductive film remaining after patterning. The second photoresist layer is divided into a second soluble portion and a second insoluble portion. Next, the first and second photoresist layers are developed, and the first and second soluble portions are removed.
US08518616B2
Reduced can be interferential streaks produced in a halftone image when using a photoreceptor support (also called a drawn tube) having been subjected to tool bit cutting processing, and provided can be an electrophotographic photoreceptor capable of obtaining high quality in response to the light printing field or the like and an image forming method employing the electrophotographic photoreceptor. Also disclosed is an electrophotographic photoreceptor possessing a cylindrical support and provided thereon, a photosensitive layer, the cylindrical support possessing a processing profile regularly formed along a central axis, provided on a circumferential surface of the cylindrical support, wherein the processing profile satisfies Formula 1: Formula 1 ΔL≧10 μm, where ΔL, represents a difference between a processing period width and another processing period width in a central axis direction of the cylindrical support in an image region.
US08518614B2
An apparatus for detecting a position of a mark from a mark signal obtained by capturing an image of the mark includes a signal processor. The signal processor is configured to set a processing window with respect to each of a plurality of positions relative to the mark signal, to calculate an even function intensity of the mark signal in the processing window with respect to each of the plurality of positions, and to detect the positions of the marks based on the even function intensity calculated with respect to each of the plurality of positions.
US08518589B2
A fuel cell system in which a low open circuit voltage (OCV) is maintained in a start-up mode and in a shut-down mode, and a method of operating the same, the method including: supplying an anode off-gas and air to the cathode in an open circuit voltage state in a start-up mode and cutting off supply of the fuel gas to the cathode in a normal operating mode; and supplying the fuel gas and air to the cathode in a shut-down mode, and if a load is cut off, purging the cathode and the anode in the OCV state.
US08518583B2
A main object of the present invention is to provide an air cathode capable of achieving both high initial discharge capacity and high capacity retention. In the present invention, the problem is solved by providing an air cathode used in a metal-air battery, comprising: an air cathode layer containing a conductive material, a particulate catalyst and a fibrous catalyst; and an air cathode current collector for collecting current of the air cathode layer, wherein the ratio of the fibrous catalyst to the total weight of the particulate catalyst and the fibrous catalyst is 10% by weight or less.
US08518575B2
A pouch-type lithium secondary battery including a battery unit having a positive electrode plate, a negative electrode plate, and a separator between the positive and negative electrode plates; electrode tabs extending from each of the positive and negative electrode plates of the battery unit, respectively; a case having a space to accommodate the battery unit; a sealing surface along the periphery of the space; and a protection circuit board electrically connected to the electrode tabs, wherein portions of each of the electrode tabs extend outside the case, and are bent in an upright position with respect to a plane of the sealing surface.
US08518570B2
A battery system includes: a battery unit formed by electrically connected in series a plurality of cell groups each made up with a plurality of battery cells electrically connected in series; a plurality of sensing lines for detecting voltages of respective battery cells in the battery unit; an integrated circuit provided to each of the cell group, to which the sensing lines for detecting voltages of respective battery cells in the cell group are connected; a case having housed therein a substrate at which a plurality of integrated circuits provided for the cell groups respectively are mounted; noise protection capacitors disposed between input terminals of the plurality of sensing lines; and at least one protection element against static electricity which is connected between the input terminals and the case.
US08518568B2
A battery module includes a plurality of battery cells and a system configured for passing a fluid past at least a portion of the plurality of battery cells in a parallel manner.
US08518567B2
An automatic battery-overcharge power disconnection device electrically coupled to a battery includes an insulating frame, a space formed by enclosing edges of the frame, two grooves formed on a lateral edge of the frame, a flexible board installed at another opposite lateral edge of the frame, an opening formed at an end of the flexible board, a knife portion disposed on an internal side of the opening; a symmetrically folded electro-conductive thin plate, having two half-plate portions and a folding portion between two half-plate portions, and passed into the opening of flexible board, such that the two half-plate portions are clamped at the flexible board, and the folding portion is situated opposite to the knife portion; two conductive electrodes, each having a connecting portion extended out from the conductive connecting portion freely, disposed in the two grooves respectively, and electrically coupled to the two half-plate portions.
US08518565B2
A glass substrate for information recording medium, said glass substrate being composed of an aluminosilicate glass containing 60-75% by mass of SiO2, 5-18% by mass of Al2O3, 3-10% by mass of Li2O, 3-15% by mass of Na2O and 0.5-8% by mass of ZrO2 relative to the entire glass components. The glass substrate for information recording medium contains neither As (arsenic) nor Sb (antimony), while containing at least one polyvalent element selected from the group consisting of V (vanadium), Mn (manganese), Ni (nickel), Nb (niobium), Mo (molybdenum), Sn (tin), Ce (cerium), Ta (tantalum) and Bi (bismuth). The molar ratio of the total amount of the polyvalent elements to the amount of Al2O3 is within the range of 0.02-0.20.
US08518559B2
There is provided conductive organic arylamine compounds. The compounds may be prepared as films and such films may be used as a hole transporting layer, an emissive layer or an electron transporting layer in organic light emitting devices.
US08518553B2
The invention relates to a layered structure comprising a first intermediate layer, said first intermediate layer comprising at least one element of group IVB, group VB or group VIB; a second intermediate layer deposited on top of said first intermediate layer, said second intermediate layer comprising a diamond-like nanocomposite composition; a diamond-like carbon layer deposited on top of said second intermediate layer. The invention further relates to the use of a substrate coated with such a layered structure for high shear and/or high impact applications and to a method to cover a substrate with such a layered structure.
US08518549B2
A method for making a coated article includes: providing a substrate; forming a prefabricated layer on a surface of the substrate by vacuum sputtering, the prefabricated layer being a metal layer containing the metal element ‘N’, or an unsaturated oxide layer containing the metal element ‘N’ and ‘M’, the ‘N’ being one or more metals selected from a group consisting of titanium, aluminum, and zinc, the ‘M’ being calcium, barium, or a mixture of calcium and barium; and thermal oxidizing the prefabricated layer to form a color layer on the substrate, the color layer being an oxide layer of the metal element ‘N’, or an oxide layer of the metal element ‘N’ and ‘M’. The color value of the color layer has a L* coordinate between 91 and 98, an a* coordinate between −1 and 1, and a b* coordinate between −2 and 2 in the CIE LAB color system.
US08518544B2
A glass sheet for a laminated glass to be fit into a frame of an automobile in a flash-mount structure, that is a glass sheet having a good strength, is provided. In the glass sheet of the present invention, the maximum value of the plane compressive stress on the edge of the glass sheet is at least 10 MPa and at most 18 MPa, and the maximum value of the plane compressive stress inside from the edge of the glass sheet is at most 2.4 MPa.
US08518537B2
An artificial dielectric material comprising a plurality of blocks of dielectric material, each block have at least one conductive fiber or wire embedded within. A method of making the material is disclosed where a plurality of strands or wires are embedded in dielectric layer which is then chopped in blocks. These blocks then fall randomly into a container in any order or pattern and are glued into a solid layer.
US08518528B2
A ceramic foam filter for molten aluminum alloys comprising an alumina silicate rich core and a boron glass shell and a chemical composition comprising: 20-70 wt % Al2O3, 20-60 wt % SiO2, 0-10 wt % CaO, 0-10 wt %; MgO and 2-20 wt % B2O3.
US08518527B2
The present invention provides a method for improving the flame retardant efficiency of a phenoxyphosphazene compound, and provides a prepreg, a laminate, and a laminate for printed circuit that are made by the method. The present invention compounds a phenoxyphosphazene compound and a dihydrobenzoxazine ring-containing compound in a halogen-free flame retardant resin composition, so as to effectively improve the flame-retardant efficiency of the phenoxyphosphazene compound. Besides, the prepreg, the laminate and the laminate for printed circuit that are made by the method for improving the flame retardant efficiency of a phenoxyphosphazene compound have excellent flame retardancy, chemical resistance, anti-CAF property, high glass transition temperature (Tg), high thermal resistance, low dielectric dissipation factor, low moisture, and low C.T.E, etc. Furthermore, epoxy resins are interfused to greatly overcome the brittleness of the benzoxazine resin, so, the cured resin has comparatively high flexural strength and good processability.
US08518526B2
An article includes a substrate having a surface and a nanofence supported by the surface. The nanofence includes a multiplicity of primary nanorods and branch nanorods, each of the primary nanorods being attached to said substrate, and each of the branch nanorods being attached to a primary nanorods and/or another branch nanorod. The primary and branch nanorods are arranged in a three-dimensional, interconnected, interpenetrating, grid-like network defining interstices within the nanofence. The article further includes an enveloping layer supported by the nanofence, disposed in the interstices, and forming a coating on the primary and branch nanorods. The enveloping layer has a different composition from that of the nanofence and includes a radial p-n single junction solar cell photovoltaic material and/or a radial p-n multiple junction solar cell photovoltaic material.
US08518521B2
Provided is a composite molded article which can increase resistance to peeling at an interface and suppress excessive peeling of a fiber-reinforced polymer material portion even when thermal shock is repeatedly applied. The composite molded article comprises a metal member using metal as a base material and having a surface; and a fiber-reinforced polymer material portion coated on at least part of the surface of the metal member and having a polymer material as a matrix and a plurality of reinforcing fibers for reinforcing the matrix. The surface of the metal member has a plurality of projections juxtaposed regularly or randomly at a pitch distance greater than diameters of the reinforcing fibers. The respective facing projections form enterable spaces which part of the matrix enters and at least part of the reinforcing fibers can enter.
US08518514B2
Simple design of a multilayer optical recording medium is achieved while suppressing interlayer crosstalk and confocal crosstalk in the multilayer optical recording medium. Simple recording and reading control by a recording and reading unit is also achieved. The multilayer optical recording medium includes at least three or more recording and reading layers deposited one above the other with intermediate layers interposed therebetween, and information can be read by light irradiation from the layers. The intermediate layers have film thicknesses of two types or less, and all the recording and reading layers except the recording and reading layer farthest from a light incident surface have substantially the same optical constant.
US08518511B2
A composite seam system including a narrow weld bead joining two panels of fabric and a seam tape applied thereon. The applied seam tape comprises a top layer, a reinforcing layer and an adhesive layer melted through the reinforcing layer and connecting the top layer to the fabric panels over the weld bead. The narrow weld bead and the small seam allowance of the fabric panels it joins allows the seam tape to be secured over the weld bead to the fabric panels while lying in a flat plane. The use of a narrow reinforcing layer of woven polyester, nylon or non-woven ultra-fine fibrous material in the seam tape allows the seam tape to be flexible enough to move with the fabric it joins, reducing the incidence of tape edge abrasion.
US08518500B2
A thermal transfer sheet includes a sheet substrate; a protective layer provided on the sheet substrate; and an adhesive layer provided on the protective layer, wherein a refractive-index difference between the protective layer and the adhesive layer is less than 0.10.
US08518498B2
The present invention relates to a liquid crystal display, wherein arrangement of liquid crystal molecules thereof is controlled by using a monomer that is polymerized by ultraviolet rays to provide a pre-tilt. To prevent damage to organic material layers when irradiating ultraviolet rays to the monomer, a blocking film made of an ultraviolet absorbing agent is formed on or over at least one such layer.
US08518489B2
Provided is a method for forming a micropattern using a mask template. The method includes: forming a mask template on a substrate, wherein the mask template has an exposure section through which a portion of the substrate is exposed to the exterior and a non-exposure section provided by a polymer material applied on the remaining portion of the substrate; supplying conductive ink to the top of the mask template to deposit the conductive ink on the non-exposure section and on the substrate exposed through the exposure section; and heat treating the conductive ink in order to extract the conductive ink nanoclusters dissolved or dispersed in the conductive ink, wherein the conductive ink nanoclusters disposed on the non-exposure section are bound to the non-exposure section to form an insulating pattern having electrical insulating property, while the conductive ink nanoclusters disposed on the substrate form a conductive pattern having electroconductive property. The method enables formation of a micropattern without any alignment error between patterns in the case of a direct printing process.
US08518484B2
This invention relates to vapor phase reagent dispensing apparatus having a bubbler tube and also a metal seal aligned and in contact with the hardened opposing flat surfaces of a top wall member and a protuberance on a side wall member, wherein the hardened opposing flat surfaces of the top wall member and the protuberance have a hardness greater than the hardness of the metal seal. The dispensing apparatus may be used for dispensing of reagents such as precursors for deposition of materials in the manufacture of semiconductor materials and devices.
US08518482B2
This invention relates to a vapor phase reagent dispensing apparatus having a bubbler tube and also a metal seal aligned and in contact with the hardened opposing flat surfaces of a top wall member and a protuberance on a side wall member, wherein the hardened opposing flat surfaces of the top wall member and the protuberance have a hardness greater than the hardness of the metal seal. The apparatus further has a temperature sensor and a source chemical level sensor extending through a centrally located portion of the top wall member and generally vertically downwardly to a sump cavity centrally located on a bottom wall member. The dispensing apparatus may be used for dispensing of reagents such as precursors for deposition of materials in the manufacture of semiconductor materials and devices.
US08518477B2
A process to apply a foamable water-based adhesive comprises combining, in a pressure-tight container having an outlet valve, a) a first aqueous polymer having a pH-value above 6 and containing a dissolved or dispersed salt that can liberate a gas, and b) a second aqueous polymer comprising an acid and having a pH-value lower than 5, and combined aqueous releasing the combined aqueous polymers from the pressure-tight container through the outlet valve onto a substrate, whereby gas bubbles are formed in the aqueous polymers leaving the valve, thus foaming the water-based adhesive.
US08518475B2
In certain example embodiments, a coated article includes respective layers including hydrogenated diamond-like carbon (DLC) and zirconium nitride before heat treatment (HT). During HT, the hydrogenated DLC acts as a fuel which upon combustion with oxygen produces carbon dioxide and/or water. The high temperature developed during this combustion heats the zirconium nitride to a temperature(s) well above the heat treating temperature, thereby causing the zirconium nitride to be transformed into a new post-HT layer including zirconium oxide that is very scratch resistant and durable.
US08518473B2
The present invention includes a method for preparing a nanoparticle filled nanocomposite material, the method including the steps of providing a plurality of nanoparticles. attaching a first layer of organic ligand to the nanoparticle via a phosphate or phosphonate linkage, covalently attaching a second layer of matrix compatible polymer to said first layer of organic ligand to produce modified nanoparticles, providing a polymer matrix and dispersing the modified nanoparticles in the polymer matrix, wherein the dispersement of the modified nanoparticles into the polymer matrix results in a nanocomposite material, and wherein the modified nanoparticles are modified such that the first layer is proximal to the nanoparticle and the second layer is distal to the nanoparticle. Also within the scope of the invention are modified nanoparticles, alternative nanocomposite materials and methods of making the same.
US08518472B2
Certain example embodiments of this invention relate to large-area transparent conductive coatings (TCCs) including carbon nanotubes (CNTs) and nanowire composites, and methods of making the same. The σdc/σopt ratio of such thim films may be improved via stable chemical doping and/or alloying of CNT-based films. The doping and/or alloying may be implemented in a large area coating system, e.g., on glass and/or other substrates. In certain example embodiments, a CNT film may be deposited and then doped via chemical functionalization and/or alloyed with silver and/or palladium. Both p-type and n-type dopants may be used in different embodiments of this invention. In certain example embodiments, silver and/or other nanowires may be provided, e.g., to further decrease sheet resistance. Certain example embodiments may provide coatings that approach, meet, or exceed 90% visible transmission and 90 ohms/square target metrics.
US08518470B2
The invention relates to shortening particle compositions that are suitable for use in preparing batter or dough products such as biscuits, pizza crusts, pot pie crusts, cinnamon rolls, or dry mixes for same. Typically, the shortening compositions are low in trans fatty acids and in saturated fatty acids. For example, the shortening particle composition may comprise less than about 3% wt. total trans fatty acids and a total of about less than about 61% wt. saturated fatty acids and trans fatty acids.
US08518467B2
Methods, devices, and compositions relating to processed grain products are shown for ground corn flour, soybean meal, cottonseed meal, and wheat middlings. An exemplary method shown is a fiber separation process for the ethanol industry corn products of Distillers Dried Grains (DDG) and Distillers Dried Grains with Solubles (DDGS) resulting from the widely used dry grind technology. A shown process and apparatus allows the removal and separate recovery of fiber-reduced products with expanded potential for use as a non-ruminant feed product in addition to the removal and separate recovery of a fiber-enriched product. The fiber enriched and fiber reduced products each have uses in the feed industry. The specific processes, devices, and compositions shown are readily adaptable to feed mills.
US08518466B2
A preparation method for selenium covered basic copper chloride includes the steps of: (a) adding crystalline basic copper chloride (TBCC), water and stabilizer in a reactor; adding sodium hydroxide solution with stirring; reacting to form a hydroxyl-modified crystalline basic copper chloride after discharge, washing, and negative pressure leaching; (b) adding the hydroxyl-modified crystalline basic copper chloride and water in the reactor, adding selenous acid with stirring; adding copper sulfate pentahydrate after reaction; forming selenium covered basic copper chloride comprising crystalline basic copper chloride, basic cuprous selenide, and basic cupric sulfate after discharge, rinsing, negative pressure filtration, and drying. The selenium covered basic copper chloride is used as feed addictives of trace elements having nonhygroscopic property, good liquidity, and stable chemical property. The selenium covered basic copper chloride is easy to incorporate with feed, low price, low cost in adding, weak acidic solubility, easy to absorb.
US08518465B2
An acid milk beverage that without the use of conventionally employed various thickening stabilizers, excels in product quality stability, and that realizes good flavor and calorie suppression, being of light type; and a process for producing the same. There is provided an acid milk beverage characterized in that there are contained polydextrose and at least one glucide selected from the group (a) consisting of glucose, fructose, sugar, trehalose, maltose, erythritol, sorbitol, xylitol, maltitol, lactitol, palatinose and galactooligosaccharide, and that the sum of these soluble solid contents is in the range of 12.0 to 17.0 mass %, containing substantially none of thickening stabilizers. Further, there is provided a process for producing the acid milk beverage.
US08518461B2
The present invention relates to a method for treating inflammation comprising administering a subject in need thereof with a therapeutically effective amount of a composition comprising bamboo vinegar or the phenolic fraction thereof. The method for preparing the phenolic fraction is also provided.
US08518460B2
A pharmaceutic composition for treating psoriasis. Ii has an active component and a carrier. The active component has a major active ingredient osthol and a group of minor active ingredients: xanthotoxol, xanthotoxin, isopimpinellin, bergapten, and imperatorine. The major active ingredient osthol accounts for at least 90% by weight of the active component, which accounts for 5-35% by weight of the overall pharmaceutic composition.
US08518453B2
The present invention is a new method and composition that enhance bone repair, formation, maintenance and slowing of bone resorption. The present invention relates to methods and compositions that enhance collagen formation, tendon health and tendon injury healing, bone maintenance and bone injury healing, and the prevention and treatment of metabolic diseases. The present invention is a part of the therapy to maintain bone health among patients with diabetic bone resorption and others with metabolic disorders. In one embodiment, the composition is a composite of hydroxyapatite and an organic matrix composed of milk pH-dependent serum proteins, i.e., bone morphogenic proteins (BMP), milk serum-derived specific proteins (MSSP), and milk serum derived proteins.
US08518445B2
The present invention teaches how to change the skin color perception, mainly the facial color from red, blue or yellow to white appearance, using quantum and optical principles. By selecting the right size and material of particles compounded in cosmetic preparations and applying the preparations to the skin, the scattering and/or emission from micro- and nanoparticles can provide a complementary color or in proximity to that complementary color of the skin color. The mixture of the color provided by the particles and the reflected color from the skin will whiten the skin or make inconspicuous of the hyperchromic portion of the skin. The invention can also be used for other applications in which the particles can be applied to a surface or blended into a material, such as, for example, automobile paint, house paint, glass color and nail polish.
US08518441B2
The present invention provides solid dispersions or solid dispersion pharmaceutical preparations containing a water-soluble polymeric substance(s) and a phenylalanine compound of the formula (1) or pharmaceutically acceptable salts thereof, wherein A represents the formula (2) and the like, B represent an alkoxy group and the like, E represents a hydrogen atom and the like, D represents a substituted phenyl group and the like, T, U and V represent a carbonyl group and the like, Arm represents a benzene ring and the like, R1 represents an alkyl group and the like, R2, R3, and R4 may be the same or different from one another and each represent a hydrogen atom, a substituted amino group and the like, and J and J′ represent a hydrogen atom and the like; production methods thereof; and solubilized pharmaceutical preparations containing a solubilizer(s) and the compound (I) or pharmaceutically acceptable salts thereof. According to the solid dispersion pharmaceutical preparations or solubilized pharmaceutical preparations, though they contain the phenylalanine compound of the formula (1) that is a poorly-soluble drug as an active ingredient, the pharmaceutical preparations having high solubility and oral absorbability can be obtained.
US08518438B2
Liquid softgel fill formulations include (i) 26-32% by weight acetaminophen, (ii) 47-51% by weight polyethylene glycol having an average molecular weight of 200-800, (iii) 3-7% by weight propylene glycol, (iv) 9-13% by weight Povidone K17, and (v) 6-10% by weight purified water. The fill formulations are free of alkali metal ions. Also disclosed are a method of preparing the above-described fill formulations and softgel capsules containing the same fill formulations.
US08518437B2
Liposomes that contain at least 10 mol % of a negatively charged lipid coupled to a non-zwitterionic moiety are stable in the blood. Liposomes containing at least 1 mol % of such lipids may be frozen safely.
US08518425B2
Anhydrous antiperspirant compositions comprising particulate antiperspirant active; capsules comprising a shear-sensitive shell which encapsulates perfume; and a carrier for the particulate antiperspirant active and capsules; wherein the capsules have a shell of cross-linked gelatin coacervate having a thickness of from 0.25 to 9 μm and providing from 10 to 40% by weight of the capsules, a volume average particle diameter of from 25 to 70 μm, a ratio of shell thickness to the average particle diameter in the range of from 1:5 to 1:120, and a Hysitron hardness in the range of from 1.5 MPa to 50 MPa.
US08518420B2
A method for growing bone cells. In one aspect, the present invention provides a method for growing bone cells, comprising the steps of (a) anodizing a titanium substrate to form an array of titanium dioxide nanotubes on a surface of the titanium substrate, (b) subjecting the anodized titanium substrate to a radio frequency plasma discharge to chemically modify the array of titanium dioxide nanotubes formed on the surface of the titanium substrate, (c) seeding bone cells onto the surface of the titanium substrate that has an array of titanium dioxide nanotubes thereon after the subjecting step, and (d) incubating the seeded bone cells for a period of time effective for the cells to grow and proliferate.
US08518407B2
Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
US08518404B2
Activatable binding polypeptides (ABPs), which contain a target binding moiety (TBM), a masking moiety (MM), and a cleavable moiety (CM) are provided. Activatable antibody compositions, which contain a TBM containing an antigen binding domain (ABD), a MM and a CM are provided. Furthermore, ABPs which contain a first TBM, a second TBM and a CM are provided. The ABPs exhibit an “activatable” conformation such that at least one of the TBMs is less accessible to target when uncleaved than after cleavage of the CM in the presence of a cleaving agent capable of cleaving the CM. Further provided are libraries of candidate ABPs, methods of screening to identify such ABPs, and methods of use. Further provided are ABPs having TBMs that bind VEGF, CTLA-4, or VCAM, ABPs having a first TBM that binds VEGF and a second TBM that binds FGF, as well as compositions and methods of use.
US08518401B1
A therapeutic agent for an inflammatory disease comprising an antibody or a CX3CR1 antagonist that inhibits an interaction of fractalkine and CX3CR1 is provided.
US08518396B2
The present invention is directed to compositions and methods of transplanting tissue, for example, in breast augmentation procedures. The compositions include adipose tissue and compounds that reduce tissue volume loss and increase survival rate of the adipose tissue when the composition is introduced into breast tissue.
US08518379B2
The present invention provides medicaments useful for reducing phosphorus serum level, especially in those subjects affected from hyperphosphatemia. More specifically, the present invention relates to pharmaceutical compositions to be administered by oral route in fasting periods, in order to absorb phosphorus compounds from fluids of the enteric tract, especially from saliva.
US08518377B2
The invention relates to pressurized gas formulations for dosage aerosols, in which a medicament is formulated suspended in TG 227 ea (1,1,1,2,3,3,3-heptafluoropropane) and/or TG 134 a (1,1,1,2-tetrafluoroethane) as a propellant, and to their use for producing a medicament. The aerosol is preferably an inhalation aerosol.
US08518365B2
The invention relates to a method and an installation for producing sulfuric acid. First of all, a product gas flow (5) containing sulfur dioxide is produced. The product gas flow (5) is supplied to a reaction chamber (1). A catalyst (3) is located in the reaction chamber (1). In the presence of the catalyst sulfur dioxide reacts to form sulfur trioxide. In further parts of the installation the resulting sulfur trioxide is converted to sulfuric acid. According to the invention, an oxidizing gas flow (6) is supplied to the reaction chamber (1) alternately with the product gas flow (5).
US08518357B2
Methods, systems, and apparatus for managing sulfur are disclosed. In some embodiments, the method comprise the following: obtaining material containing sulfur; refining the material to develop a high sulfur content heavy fraction fuel oil and a low sulfur content light fraction fuel oil; burning the low sulfur content light fraction fuel oil in apparatus that emit to the atmosphere; burning the high sulfur content heavy fraction fuel oil to produce energy thereby generating flue gas containing sulfur oxide; and removing and disposing of sulfur in the flue gas using a sulfur sequestration system that includes utilizing sulfur removed from the flue gas to form a brine material.
US08518356B2
A feed gas comprising CO2, H2S and H2 is treated to produce an H2-enriched product and an H2S-lean, CO2 product. The feed gas is separated to provide the H2-enriched product and a stream of sour gas. The stream of sour gas is divided into two parts, one of which is processed in an H2S removal system to form one or more streams of sweetened gas, and the other of which bypasses the H2S removal system, the stream(s) of sweetened gas and the sour gas bypassing the H2S removal system then being recombined to form the H2S-lean, CO2 product gas. The division of the sour gas between being sent to and bypassing the H2S removal system is adjusted responsive to changes in the H2S content of the sour gas, so as to dampen or cancel the effects of said changes on the H2S content of the H2S-lean, CO2 product gas.
US08518355B2
A method of using a catalyst comprises exposing a catalyst to at least one reactant in a chemical process. The catalyst comprises copper and a small pore molecular sieve having a maximum ring size of eight tetrahedral atoms. The chemical process undergoes at least one period of exposure to a reducing atmosphere. The catalyst has an initial activity and the catalyst has a final activity after the at least one period of exposure to the reducing atmosphere. The final activity is within 30% of the initial activity at a temperature between 200 and 500° C.
US08518353B1
Circulating dry scrubbing (CDS) systems and methods utilizes a particle classification unit operation to separate unreacted sorbent (such as lime, limestone, or sodium-based sorbent) such that a reactive fraction of the cut stream may be selectively recovered to a flue gas scrubbing system. This reduces the amount of fresh sorbent that must be supplied for pollutant removal.
US08518348B2
A histological specimen retaining device for processing tissue. The histological specimen retaining device comprises a foldable permeable sheet having edges and a permeable target disposed on the foldable permeable sheet within the edges of said sheet thereby providing extended flap portions. The extended flap portions are foldable to overlap the target. The histological specimen retaining device also comprises a malleable securing strip attached to the permeable sheet of a length sufficient to secure said folded flap portions overlapping said target.
US08518343B2
Solid matter in a cavity is used to produce a solution of at least one solid matter in a solvent. The solid matter which is soluble in the solvent in initially covered and/or surrounded in the cavity by a medium which is insoluble in a solvent, such that dissolving of the solid matter is prevented. Subsequently the solvent is guided to the cavity and the medium which is insoluble in the solvent is treated in such a manner that contact is made between the solvent and the soluble solid matter, enabling the solid matter to dissolve in the solvent. Solutions including two or more solid matter can be produced in an advantageous manner.
US08518332B2
An air pollution control apparatus 10 according to an embodiment of the present invention has a denitration catalyst layer 13 that removes NOx in flue gas 12, and atomizes HCl into the flue gas 12 to oxidize Hg, and also includes a swirling-flow generating member 30A that includes a swirling-flow generating-member body being partitioned to correspond to each passage of the denitration catalyst layer 13 and a plurality of swirling-flow generating vanes arranged on the partition inner walls to generate a turbulent flow, on an inlet 13a side of the denitration catalyst layer 13. With this configuration, a laminar flow of the flue gas 12 in a flue gas duct 19 is changed to a swirling flow, thereby enabling to increase a contact time between the flue gas 12 and a denitration catalyst and to improve the oxidation reaction efficiency between Hg in the flue gas 12 and the denitration catalyst.
US08518327B2
The invention provides a system and method for dissolution testing. The system includes multiple dissolution vessels and a dose carrier positioned above the dissolution vessels. The dose carrier holds multiple removable carousels that receive individual doses for dissolution tested. Carousels that receive tablets or sinkers typically have a first configuration, while carousels that receive baskets typically have a second configuration. The two different configurations of carousels are interchangeable on the same dose ring. The system further includes a drive head positioned above the dose carrier, the drive head having a basket arbor and a mixing paddle removably and interchangeably attached. A pipettor integral with the system transfers sample aliquots having volumes in the range of 50 μl to 1 ml from the dissolution vessels to wells of an external receptacle.
US08518325B2
There is described a unit for sterilizing a web of packaging material, the unit having a bath containing a sterilizing agent in which the web is advanced continuously; and an aseptic environment containing sterile air, connected to an outlet of the bath, and housing drying means for removing residual sterilizing agent from the web; the aseptic environment is divided into two regions by a narrow-section channel, along which the web travels, and which is sized to produce a predetermined difference in pressure between the two regions, and so force air into the channel from the higher-pressure region to the lower-pressure region to dry the web.
US08518313B2
Disclosed herein is a process for heat treating a foamed copolyester thermoplastic sheet structure in order to achieve a sheet structure having a compression set resistance (as determined according to ISO 1856, 22 hours, 70° C., 30% compression) of less than 11%. Heat treating involves annealing followed by at least two cycles of pre-compression at approximately the annealing temperature.
US08518304B1
The present invention features additions of nanostructures to interconnect conductor particles to: (1) reduce thermal interface resistance by using thermal interposers that have high thermal conductivity nanostructures at their surfaces; (2) improve the anisotropic conductive adhesive interconnection conductivity with microcircuit contact pads; and (3) allow lower compression forces to be applied during the microcircuit fabrication processes which then results in reduced deflection or circuit damage. When pressure is applied during fabrication to spread and compress anisotropic conductive adhesive and the matrix of interconnect particles and circuit conductors, the nano-structures mesh and compress into a more uniform connection than current technology provides, thereby eliminating voids, moisture and other contaminants, increasing the contact surfaces for better electrical and thermal conduction.
US08518288B2
A process for forming thermoelectric nanoparticles includes the steps of forming a core material reverse micelle or micelle, adding a bismuth containing compound to the core material reverse micelle or micelle forming a reverse micelle or micelle having the bismuth containing compound dispersed therein, adding a tellurium containing compound with the formed micelle or reverse micelle in the presence of a reducing agent that alloys with the bismuth containing compound forming composite thermoelectric nanoparticles having a core and shell structure, and washing the core and shell nanoparticles in a solvent mixture including ammonium hydroxide, water and methanol wherein the core and shell nanoparticles remain un-agglomerated and have a particle size of from 1-25 nanometers.
US08518285B2
A substrate section for a flexible display device is disclosed. The substrate section includes: a first substrate, a second substrate disposed above a center region of the first substrate, a reinforcing layer disposed between the first and second substrates, configured to reinforce adhesion between the first and second substrates, and a barrier layer disposed above the second substrate and surrounding side surfaces of the second substrate and of the reinforcing layer.
US08518279B1
A method for providing a capping layer configured for an energy assisted magnetic recording (EAMR) head including at least one slider. The method comprises etching a substrate having a top surface using an etch to form a trench in the substrate, the trench having a first surface at a first angle from the top surface and a second surface having a second angle from the top surface. The method further comprises providing a protective coating exposing the second surface and covering the first surface, removing a portion of the substrate including the second surface to form a laser cavity within the substrate configured to fit a laser therein, and providing a reflective layer on the first surface to form a mirror, the cavity and mirror being configured for alignment of the laser to the laser cavity and to the mirror and for bonding the laser to the laser cavity.
US08518272B2
A system for separating components of a composition according to density. The system includes a torque generating device, a separation device, and a housing. The separation device separates the composition into different components according to density. The housing accommodates the separation device. The housing includes a base having an interface that transfers torque from the torque generating device to the separation device, a cover, and a conduit for introducing the composition into the separation device without opening the cover.
US08518269B2
A low cost method and system for treating water, which will be used in an industrial process, is provided. A system of the invention generally includes at least one containing means, at least one coordination means, at least one chemical application means, at least one mobile suction means, and at least one filtration means. The coordination means can control the necessary processes depending on the system needs (e.g., water quality or purity). The method and system of the invention purifies the water and eliminates suspended solids without the need of filtering the totality of the water volume, but only filtering a small fraction of up to 200 times less than the flow filtered by a conventional water treatment filtration system.
US08518263B2
Hydrophobic, asymmetric membranes are formed integrally from elastomeric polymers. The membranes have a dense, discriminating layer and a thick, porous support layer and require no other support. The membranes of the invention provide an economic advantage over prior art composite membranes used for separating target organics from a mixture. Using the methods of the invention it is possible to separate two or more organic components wherein discrimination is made on the basis of molecular size.
US08518260B2
A method of controlling diffusive sodium transport from the dialysate solution to the blood of a patient undergoing hemodialysis treatment or from the blood to the dialysate solution includes calculating SNa+average, an average of the patient's historic serum sodium concentrations, and estimating SNa+estimated, the patient's pre-dialysis serum sodium concentration, based on the average of the patient's measured historic pre-dialysis serum sodium concentrations, SNa+measured. The method enables adjusting DNa+, the sodium concentration of the dialysate solution, based on the average of the patient's historic serum sodium concentrations, SNa+average, if needed, and performing the dialysis treatment of the patient using a dialysate solution containing a sodium concentration DNa+.
US08518255B2
A water purifier that performs back washing extremely effectively even when raw water contains a large amount of impurities includes an attachment main body including an inflow passage into which raw water from an inflow port flows, and first and second outflow passages through which water flows toward outflow ports; and a water purification main body that is attached rotatably to the attachment main body and includes a first flow passage, a second flow passage, and a third flow passage, a first filter member disposed between the first flow passage and the second flow passage and a second filter member disposed between the second flow passage and the third flow passage, wherein, when the attachment main body and the water purification main body are in a rotation position corresponding to a water purification mode, the first flow passage and the second flow passage communicate with the inflow passage and the first outflow passage, respectively, and when the attachment main body and the water purification main body are in a rotation position corresponding to a back washing mode, the third flow passage and the first flow passage communicate with the inflow passage and the second outflow passage, respectively, whereby the first filter member is back washed.
US08518252B1
The present invention provides a new and improved system for on-site and on-demand production of sterile water for injection (SWFI) from potable water or water that meets the EPA drinking water quality upon preconditioning, in conjunction with reconstitution of IV fluids using dry chemicals or concentrate pre-filled bags, suitable for use at a site under non-clean room environment conditions, and capable of adjusting feed water temperatures. The present invention includes a water temperature conditioning module, a water preconditioning module, a hydrothermal processor, a fluid staging compartment, and combinations and variations thereof.
US08518251B2
A strainer device (1) is described, which may be mounted on a pour-out of a container by way of fastening means (12) on a lower side (14) which may face the container (3). The strainer device (1) comprises a plurality of sieve elements (10) which are pivotably arranged on a sieve element holder (15) in a plane parallel to the lower side (14) of the strainer device (1), at least partly separated from one another by way of slots (11). As a whole a flexible, bendable comb-like strainer device (1) is formed, which is may be fastened with a fixation device (2) on the pour-out of the container in a simply releasable manner. The strainer device (1) is preferably designed of a heat-resistant plastic, wherein stainless steel may also be applied completely or partly for the design of the sieve elements (10) and/or the sieve element holder (15).
US08518246B2
A device for continuously, periodically monitoring water for microbial germs, comprising a reactor and at least one reagent feed line into the reactor and at least one metering device for reagents as well as at least one measuring device for detecting the presence of microorganisms, wherein the reactor comprises a reactor chamber and a filtrate chamber, which is separated from said reactor chamber by means of a filter, a water feed line as well as a reagent feed line empty into the reactor chamber and at least one water discharge line leads out of the filtrate chamber, and a controller is set up to use pump/valve means to lead a predefinable quantity of water into the reactor chamber and through the filter as well as to introduce a predefinable quantity of reagent into the reactor chamber.
US08518244B2
This invention relates to an improved hydrotreating process for removing sulfur from naphtha and distillate feedstreams. This improved process utilizes a hydrotreating zone, an acid gas removal zone, and a pressure swing adsorption zone having a total cycle time of less than about 30 seconds for increasing the concentration of hydrogen utilized in the process.
US08518243B2
The fuel properties of petroleum hydrocarbon waste having an API gravity varying from about 5 to 30 are improved by heating the hydrocarbon to a temperature of about 35° C. to 90° C. and mixing the heated hydrocarbon stream with a suitable solvent to reduce the viscosity of the hydrocarbon, which is then separated by a centrifuge to obtain an aqueous phase stream, an oil phase stream, and a separated solids stream. The oil phase stream has a viscosity range of about 250 centipoise (cP) to about 1000 cP. The oil phase stream is utilized in a refinery, while a slurry fuel is prepared with the separated solids stream and aqueous phase stream as a feedstock for road asphalt, a fuel for a combustor, or a fuel for a gasification process. The oil phase stream is used for fuels and feedstock for making carbon fiber.
US08518239B2
This invention is directed to hydrocracking catalysts and hydrocracking processes employing a magnesium aluminosilicate clay. The magnesium aluminosilicate clay has a characteristic 29Si NMR spectrum. The magnesium aluminosilicate clay is the product of a series of specific reaction steps. Briefly, the magnesium aluminosilicate clay employed in the catalyst and process of the present invention is made by combining a silicon component, an aluminum component, and a magnesium component, under aqueous conditions and at an acidic pH, to form a first reaction mixture and subsequently the pH of the first reaction mixture is adjusted to greater than about 7.5 to form a second reaction mixture. The second reaction mixture is allowed to react under conditions sufficient to form the magnesium aluminosilicate clay. The resulting magnesium aluminosilicate clay combines high surface area and activity for use in hydrocracking catalysts and processes.
US08518238B2
A method for inhibiting the formation of fouling materials during hydrocarbon processing is provided. Hydrocarbon media, which is undergoing treatment with a basic wash and contains carbonyl compounds is contacted with hydroxylamine and naphthalene sulfonate to inhibit the formation of fouling materials and to minimize the deposition of fouling compounds that may occur during hydrocarbon processing.
US08518237B2
The service life of amperometric electrochemical oxygen sensors is increased by operating the electrodes of such sensors at a polarization voltage suitable for measuring the oxygen content of samples only during calibration or when measuring such samples and thereafter modulating the polarization voltage to a lower voltage such that substantially no electrical current is produced by the electrodes.
US08518231B2
The invention relates to a process for production of diaryl carbonate combined with the electrolysis of the resultant alkali metal chloride-containing process wastewater. The process according to the invention makes possible, inter alia, improved utilization in electrolysis of the alkali metal chloride-containing solution obtained in the production of diaryl carbonate.
US08518230B2
A method of reducing tin whisker formation including steps of a) providing a tin or tin-alloy bath containing one or more sources of tin and one or more crystal plane orientation enhancing compounds selected from imides, imines, amides, polyamides, amines, polyamines, polyols, dibutyl thiourea, allyl thiourea, amino thiazole, rhodanine, sulfosalicylic acid and sulfamides; and b) electrodepositing a layer of tin or tin-alloy on a substrate, the tin or tin-alloy layer is free of crystal planes or equivalent planes thereof forming an angle of 5° to 22° with an adjacent crystal plane or an equivalent plane.
US08518224B2
The present invention provides a plating apparatus with multiple anode zones and cathode zones. The electrolyte flow field within each zone is controlled individually with independent flow control devices. A gas bubble collector whose surface is made into pleated channels is implemented for gas removal by collecting small bubbles, coalescing them, and releasing the residual gas. A buffer zone built within the gas bubble collector further allows unstable microscopic bubbles to dissolve.
US08518222B2
A continuous plating apparatus, when the number of the workpieces simultaneously transferred in the plating tank in a completely immersed state is N, (N+1) cathode relay members that extend in a workpiece transfer direction and (N+1) power supply units being provided outside the plating tank, anode terminals of the power supply units being connected to opposed anodes that are provided in the plating tank, cathode terminals of the power supply units being respectively connected to the cathode relay members so that power is supplied to each of the workpieces transferred in the plating tank from a corresponding power supply unit among the power supply units through a corresponding cathode relay member among the cathode relay members, and each of the power supply units being able to be controlled by constant current control when being transferred in the plating tank in a completely immersed state, by current gradual increase control when being carried into the plating tank in a partially immersed state, and by current gradual decrease control when being carried out from the plating tank in a partially immersed state.
US08518221B2
Certain example embodiments of this invention relate to techniques for making a coated article including a transparent conductive indium-tin-oxide (ITO) film supported by a heat treated glass substrate. A substantially sub-oxidized ITO or metallic indium-tin (InSn) film is sputter-deposited onto a glass substrate at room temperature. The glass substrate with the as-deposited film thereon is subjected to elevated temperatures. Thermal tempering or heat strengthening causes the as-deposited film to be transformed into a crystalline transparent conductive ITO film. Advantageously, this may reduce the cost of touch panel assemblies, e.g., because of the higher rates of the ITO deposition in the metallic mode. The cost of touch-panel assemblies may be further reduced through the use of float glass.