US08063543B2
A piezoelectric thin film element includes a substrate, a lower electrode, a piezoelectric thin film, and an upper electrode. The lower electrode, the piezoelectric thin film and the upper electrode are formed on the substrate. The piezoelectric thin film includes a polycrystal thin film including crystal grains, an alkali niobium oxide based perovskite structure represented by a general formula: (K1-xNax)NbO3 (0.4
US08063540B2
A design and a manufacturing method of ultrasound transducers based on films of ferro-electric ceramic material is presented, the transducers being particularly useful for operating at frequencies above 10 MHz. The manufacturing technique can involve tape-casting of the ceramic films, deposition of the ceramic films onto a substrate with thick film printing, sol-gel, or other deposition techniques, where manufacturing methods for load matching layers and composite ceramic layers are described. The designs also involve acoustic load matching layers that provide particularly wide bandwidth of the transducers, and also multi-band operation of the transducers. The basic designs can be used for elements in a transducer array, that provides the frequency characteristics of the single element transducers, for array steering of the focus and possibly also direction of a pulsed ultrasound beam at high frequencies and multi-band frequencies.
US08063533B2
An electronic device having a piezoelectric pump. The electronic device includes: an audio input section; an audio recording section recording input sound from the audio input section; a piezoelectric pump cooling air by a piezoelectric element; a drive circuit driving the piezoelectric element; and a control circuit monitoring and controlling operation of the audio input section, the audio recording section, and the drive circuit, wherein when an operation mode being monitored is an audio recording mode, in which the input sound is used for recording by the audio recording section, the control circuit controls the drive circuit to decrease the amount of air flow exhausted outside from the piezoelectric pump, and when the operation mode being monitored is another mode without audio recording, the control circuit maintains the amount of the air flow.
US08063515B2
A system for compensating a power transmission grid is provided. The system includes one or more non-conventional power generating sources that are connected to the power transmission grid. At least one series compensation circuit is connected to at least a portion of the power transmission grid, to compensate the power transmission grid. At least one damping circuit is connected to at least a portion of the power transmission grid, and it mitigates subsynchronous series resonance caused by the series compensation circuit on the power transmission grid.
US08063513B2
The solution controls electric operational power to be fed to an amplifier. The control can be carried out, for instance, in accordance with a predetermined signal. The operational power is fed to the amplifier with a voltage source unit and a current source unit, and the operational voltage that the voltage source unit feeds to the amplifier is controlled. The current source unit feeds at least some of the operational electric current of the amplifier.
US08063511B2
Systems and methods for storing and releasing energy comprising directing inlet air into a vertical cold flue assembly, a portion of moisture being removed from the air within the cold flue assembly. The air is directed out of the cold flue assembly and compressed. The remaining moisture is substantially removed and the carbon dioxide is removed from the air by adsorption. The air is cooled in a main heat exchanger such that it is substantially liquefied using refrigerant loop air. The substantially liquefied air is directed to a storage apparatus. The refrigerant loop air is cooled by a mechanical chiller and by a plurality of refrigerant loop air expanders. In energy release mode, working loop fluid warms the released liquid air such that the released liquid air is substantially vaporized, and the released liquid air cools the working loop fluid such that the working loop fluid is substantially liquefied. A portion of the released liquid air is directed to the at least one generator and used as bearing air lor the at least one generator. The substantially vaporized air is directed to a combustion chamber and combusted with a fuel stream. Combustion gas may be directed from the combustion chamber to at least one expander, the expanded combustion gas split into two portions. The first portion may be directed to a first heat exchanger, and the second portion may be directed to a second heat exchanger such that the second portion heats and substantially vaporizes the released liquid air.
US08063508B2
A power control system is described that reuses current from segregated circuits of the mobile device. In some embodiments, the segregated circuits (or “sections”) can be “stacked” in series (with respect to the power supply) such that power is more efficiently used. The power can be more efficiently used by arranging a first section to reuse current that supplies power to a second section. A power control unit can be used to control regulators.
US08063493B2
A sacrificial substrate for fabricating semiconductor device assemblies and packages with edge contacts includes conductive elements on a surface thereof, which are located so as to align along a street between each adjacent pair of semiconductor devices on the device substrate. A semiconductor device assembly or package includes a semiconductor device, a redistribution layer over an active surface of the semiconductor device, and dielectric material coating at least portions of an outer periphery of the semiconductor device. Peripheral sections of contacts are located on the peripheral edge and electrically isolated therefrom by the dielectric coating. The contacts may also include upper sections that extend partially over the active surface of the semiconductor device. The assembly or package may include any type of semiconductor device, including a processor, a memory device, and emitter, or an optically sensitive device.
US08063492B2
A multi-chip stacked package primarily comprises a chip carrier, a first chip disposed on the chip carrier, a plurality of die-attaching bars, a second chip stacked on the first chip by the adhesion of the die-attaching bars, and a plurality of bonding wires electrically connecting the first chip to the chip carrier. The die-attaching bars are formed on the first chip in a specific pattern and have an adhesive surface away from the first chip for adhering the second chip. The bonding wires have a loop height lower than the adhesive surface in a manner that specific sections of the bonding wires are embedded in the corresponding die-attaching bar from the adhesive surface. Accordingly, the die-attaching bars can modify and fasten the bonding wires in advance to avoid collapse and deformation of the bonding wires during stacking of the second chip and encapsulating processes.
US08063482B2
A technique to fabricate a package. A thin wafer supported by a wafer support substrate (WSS) is formed. The WSS-supported thin wafer layer is diced into a plurality of WSS-supported thin dice. A WSS-supported thin die is bonded to a first heat spreader (HS) to form a HS-reinforced thin die.
US08063470B1
A leadframe for use in fabricating a no lead semiconductor package contains connecting bars between individual electrical contact pads. For embodiments having a die pad, the leadframe further includes connecting bars between the contact pads and the die pad. The lower surfaces of the connecting bars are coplanar with the lower surfaces of the contact pads and/or the die pad, and the upper surfaces of the connecting bars are recessed with respect to the upper surfaces of the contact pads and/or the die pad. The semiconductor package is fabricated by encapsulating the die and the leadframe in a molding compound and then removing the connecting bars. The leadframe is typically formed by half etching a metal sheet to form the connecting bars. The connecting bars are removed from the encapsulated package by a selected cutting, sawing, or etching means, based on a predetermined pattern.
US08063469B2
Structure and method for fabricating a system on chip with an on-chip RF shield including interconnect metallization is described. In one embodiment, the system on chip includes an RF circuitry disposed on a first portion of a top surface of a substrate, and a semiconductor circuitry disposed on a second portion of the top surface of the substrate. An interconnect RF barrier is disposed between the RF circuitry and the semiconductor circuitry, the interconnect RF barrier coupled to a ground potential node.
US08063468B2
A semiconductor device includes a semiconductor chip, a moisture resistant ring provided in the semiconductor chip and having a chamfered flat part in a position corresponding to a corner of the semiconductor chip, and a first monitor pattern formed inside the moisture resistant ring. At least a part of the first monitor pattern is disposed inside an n-sided polygonal area (n is a natural number which is 4 or higher than 4) situated within the moisture resistant ring, and outside a quadrangular area situated inside the n-sided polygonal area. The n-sided polygonal area has a vertex at least at each of a first end and a second end of the chamfered flat part, and the quadrangular area has a vertex at least at a middle point of the chamfered flat part.
US08063462B2
A semiconductor device includes a semiconductor substrate having a first surface in which a light-receiving portion and electrodes are provided. The semiconductor substrate has a penetrating wiring layer connecting the first surface and the second surface. A light-transmissive protective member is disposed on the semiconductor substrate so as to cover the first surface. A gap is provided between the semiconductor substrate and the light-transmissive protective member. A protective film is formed at a surface of the light-transmissive protective member. The protective film has an opening provided at a region corresponding to the light-receiving portion.
US08063457B2
A high-density impurity diffused layer of an identical conduction type to the semiconductor substrate on which the impurity is doped higher in density than the semiconductor substrate around the diffuse resistance region is provided, one side of the electrodes is formed extending to the high-density impurity diffused layer and the diffused resistance region and the high-density impurity diffused layer are connected in a semiconductor strain gauge that is formed on the surface of the semiconductor substrate of a fixed conduction type and is provided with the diffused resistance region of opposite conduction type to the semiconductor substrate and is provided with electrodes on both ends of the diffused resistance region.
US08063450B2
The present invention relates to vertical nanowire transistors with a wrap-gated geometry. The threshold voltage of the vertical nanowire transistors is controlled by the diameter of the nanowire, the doping of the nanowire, the introduction of segments of heterostructures in the nanowire, the doping in shell-structures surrounding the nanowire, tailoring the work function of the gate stack, by strain engineering, by control of the dielectrica or the choice of nanowire material. Transistors with varying threshold voltages are provided on the same substrate, which enables the design of advanced circuits utilizing the shifts in the threshold voltages, similar to the directly coupled field logic.
US08063438B2
In a vertical-type memory device and a method of manufacturing the vertical-type memory device, the vertical memory device includes an insulation layer pattern of a linear shape provided on a substrate, pillar-shaped single-crystalline semiconductor patterns provided on both sidewalls of the insulation layer pattern and transistors provided on a sidewall of each of the single-crystalline semiconductor patterns. The transistors are arranged in a vertical direction of the single-crystalline semiconductor pattern, and thus the memory device may be highly integrated.
US08063435B2
A semiconductor memory in which a gate insulating film (tunnel insulating film) in a memory cell provides higher operational reliability. The semiconductor memory includes an insulating film 3 between a silicon substrate 1 and a gate electrode 4. The insulating film 3 is composed of a silicon oxide film 3f, a silicon nitride film 3d and a silicon oxide film 3b, stacked in this order between the silicon substrate and the gate electrode from the side of the silicon substrate 1. There are provided hydrogen occluding films 3a, 3c and 3e on an interface between the silicon oxide film 3f and the silicon nitride film 3d, on an interface between the silicon nitride film 3d and the silicon oxide film 3b and on an interface between the silicon oxide film 3b and the gate electrode 4 (FIGS. 1A and 1B).
US08063431B2
An electrically erasable programmable read only memory (EEPROM) is disclosed. The EEPROM includes a tunneling region in a semiconductor substrate, a control gate region in the semiconductor substrate and separated from the tunneling region by a device isolating layer, a tunnel oxide layer in a trench in the semiconductor substrate between the tunneling region and the control gate region, and a polysilicon layer on the tunnel oxide layer.
US08063420B2
A field-effect transistor with improved moisture resistance without an increase in gate capacitance, and a method of manufacturing the field-effect transistor are provided. The field-effect transistor includes: a T-shaped gate electrode on a semiconductor layer; and a first highly moisture-resistant protective film including one of an insulating film and an organic film having high etching resistance, the first highly moisture-resistant protective film being located above the T-shaped gate electrode, over all of a region in which the T-shaped gate electrode is located. A cavity is located between the semiconductor layer and the first highly moisture-resistant protective film, below a canopy of the T-shaped gate electrode. An end surface of the cavity is closed by a second highly moisture-resistant film.
US08063419B2
An integrated circuit and component is disclosed. In one embodiment, the component is a compensation component, configuring the compensation regions in the drift zone in V-shaped fashion in order to achieve a convergence of the space charge zones from the upper to the lower end of the compensation regions is disclosed.
US08063414B2
A standard cell, placed between a power rail and a ground rail in an integrated circuit, has active areas with connecting arms that extend beneath the power rail and ground rail. The connecting arms conduct current between the power and ground rails and the source regions of transistors in the active areas. The connecting arms include segments extending from these source regions to points beneath the power and ground rails, and segments running longitudinally beneath the power and ground rails. The connecting arms replace metal wiring that would otherwise be required, enabling the size of the standard cell to be reduced.
US08063411B2
A transparent layer and a phosphor layer are covered on the LED chip for increasing light emission efficiency and evenness of the LED. Based on angle-dependent emission strength of the LED chip, the phosphor layer is designed with different thickness or contains different phosphor powder concentration in different section. The lights emitted with different strength from different angle of the LED chip are transformed into uniform compound lights after passing through the phosphor layer that has different thickness or phosphor powder concentration. Micro structures capable of destroying the full reflection occurred on the incident lights are further configured on both the inner and outer surfaces of the phosphor layer to increase the light emission efficiency.
US08063403B2
An impurity element imparting one conductivity type is included in a layer close to a gate insulating film of layers with high crystallinity, so that a channel formation region is formed not in a layer with low crystallinity which is formed at the beginning of film formation but in a layer with high crystallinity which is formed later in a microcrystalline semiconductor film. Further, the layer including an impurity element is used as a channel formation region. Furthermore, a layer which does not include an impurity element imparting one conductivity type or a layer which has an impurity element imparting one conductivity type at an extremely lower concentration than other layers, is provided between a pair of semiconductor films including an impurity element functioning as a source region and a drain region and the layer including an impurity element functioning as a channel formation region.
US08063401B2
A probe electrode structure on a substrate is described, comprising a first probe electrode and a neighboring second probe electrode on a layer sequence that generally includes, in a direction from the substrate to the probe electrodes, an electrically conductive bottom layer, an electrically insulating center layer and a electrically conductive top layer. The probe-electrode structure of the invention provides a means to detect an undercutting of the first probe electrode in an etching step that aims at removing the top layer from regions outside the first probe electrode. An undercutting that exceeds an admissible distance from the first edge of the first electrode will remove the first top-layer probe section in the first probe opening, which causes a detectable change of the electrical resistance between the first and second probe electrodes.
US08063391B2
The present invention provides a light-transmitting electromagnetic wave-shielding material for use in displays or in-vehicle panels each having a polarizing plate or a retardation plate, wherein the light-transmitting electromagnetic wave-shielding material undergoes no generation of light interference fringes and is satisfactory in visibility even through sunglasses, goggles, glare-proof panels or glare-proof window materials having polarizing capability. By using unstretched light-transmitting organic polymer materials low in molecular orientation or small in molecular orientation unevenness as the base substrate of an electromagnetic wave-shielding layer, the light-transmitting electromagnetic wave-shielding material excellent in light interference fringe prevention capability can be obtained.
US08063390B2
An electron cooling system and method for increasing the phase space intensity and overall intensity of ion beams in multiple overlap regions, including a vacuum chamber to allow a single electron beam to be merged and separated with multiple ion beams, an electron supply device including a cathode to generate the electron beam, an electron collector device including a collection plate to collect the electron beam, multiple magnetic field generation devices to guide the electrons on their desired trajectories, and multiple electrodes to set the velocity of the electron beam independently in each overlap region. By overlapping the electron and ion beams, thermal energy is transferred from the ion beams to the electron beam, which allows an increase in the phase space density and overall density of the ion beams. Advantageously, the electron cooling system uses multiple magnetic field generation devices to guide the electrons into and out of multiple, separate, ion beam overlap regions, allowing the single electron beam to cool an ion beam in more than one overlap region. Advantageously, the electron cooling system uses electrodes to control the mean electron beam velocity in each overlap region, allowing for mitigation of electron beam emittance growth caused by scattering that occurs exterior to the overlap regions. Advantageously, the electrodes used to control the mean electron beam velocity in each overlap region allow for a single electron beam to achieve different velocities to match different desired ion beam velocities in the multiple overlap regions.
US08063382B2
In one embodiment, an air mover may include a first electrode, a second electrode and an ionization device to selectively ionize molecules in an electric field between the first and second electrodes. The ionized molecules can drive airflow between the first and second electrodes. In certain embodiments, the ionization device has an operational characteristic that prevents ionization of oxygen so that the airflow is ozone-free.
US08063369B2
The invention relates to a bolometer element, a bolometer cell, a bolometer camera, and a method for reading a bolometer cell. The bolometer cell comprises several bolometer elements. Each bolometer element comprises a first bolometer having a first heating resistance for sensing radiation power acting on the element, and a second bolometer having a second heating resistance, and in each bolometer element the first and second bolometers are electrically connected to each other in such a way that the heating resistance (611) of the first bolometer can be biased with the aid of a voltage through the heating resistance of the second bolometer in order to amplify the radiation power detected with the aid of the connection. With the aid of the invention, it is possible to implement an extremely sensitive bolometer camera.
US08063363B2
A method, apparatus and computer readable medium for charged particle beam inspection of a sample comprising at least one sampling region and at least one skip region is disclosed. The method, apparatus and computer readable medium comprise receiving an imaging recipe which at least comprises information of the area of the sampling and skip regions; calculating a default stage speed according to the imaging recipe; calculating an alternative stage speed at least according to the default stage speed, the sampling region area information, and the skip region area information; calculating at least one imaging scan compensation offset at least according to the alternative stage speed; and inspecting the sample at the alternative stage speed while adjusting the motion of the charged particle beam according to the imaging scan compensation offsets, such that the charged particle beam tightly follows the motion of the stage and images only the sampling regions on the sample.
US08063352B2
A color separation filter (100), for a solid state image sensor includes a micro lens array (108) adapted to collect a full color spectrum light source (104), a mask layer (120) is attached to the micro lens array (108), the mask layer (120) includes plurality of openings (124), each opening is positioned in front of a single micro lens from the micro lens array. Additionally it includes a first array of prisms (204), each prism is positioned in front of each of the openings, a second array of prisms (212) is attached to the first array of prisms with an optical glue layer (208). Each prism from the first array of prisms is positioned in front of a prism from the second array of prisms to create a symmetrical optical path for the color spectrum light source (304).
US08063349B2
A solar heliostat and system are described with various characteristics particularly suitable for concentrating systems with a relatively large number of small heliostats. Other features contribute to high performance, low cost, high durability, and high temperature operation, such as desired for high efficiency thermal power generation.
US08063348B1
A system for detection of optical type devices being used by an enemy sniper subject without alerting the enemy is shown. A coherent laser beam of a wave length in the visible color range, is sent along an axis and passing through a beam splitter device. A detection means is arranged to generate a signal when it detects retro-reflections from the target optical devices or subject including clutter reflections in a 180 degree direction relative to axis. The detection means is coaxially mounted with the source of illumination with a second detection means off axis therefrom to generate a second detection signal when it detects clutter reflections from the target optical devices or subject. A comparator means forms a difference signal between the retro-reflected detection signal and the second detection signal and indicates when the difference signal exceeds a predetermined threshold.
US08063339B2
A spark gap device is described such as for use in welding systems. The device receives a high voltage, low current input signal and produces high frequency waveform output. The device includes one or more toroidal members surrounding a rod-like member with an annular gap therebetween. When the input signal is applied to the device, arcs are established in the gap between the toroidal members and the rod-like member, producing the high frequency output. Erosion and loci of arcs between the toroidal members and the rod-like member are distributed, resulting in extended life of the assembly. The gaps are also shielded from contaminants and moisture by an insolative body that maintains the toroidal members and the rod-like member in place with respect to one another.
US08063338B2
A system, method and masking arrangement are provided of enhancing the width of polycrystalline grains produced using sequential lateral solidification using a modified mask pattern is disclosed. One exemplary mask pattern employs rows of diamond or circular shaped areas in order to control the width of the grain perpendicular to the direction of primary crystallization.
US08063327B2
A switch assembly includes a shell, and a push button including a fixing member, a pushing member, an elastic member and an electrical-conductive member. A shell includes an upper surface and a cavity extending from the upper surface to a lower surface opposite to the upper surface. The fixing member is received in the cavity of the shell. The pushing member is slidably received in the fixing member and exposed out of the cavity. The elastic member is positioned between the pushing member and the shell. The electrical-conductive member is mounted on an end of the pushing member.
US08063321B2
A weighing apparatus adapted for use in an existing conveyor, and a method for attaching a weighing apparatus to an existing conveyor without removing components or modifying the conveyor. The apparatus comprises a roller, a load cell, a vertical support and a cross member. The cross member is secured to adjacent existing idlers or alternatively to the frame supporting the existing conveyor via non-invasive means that do not require the existing conveyor or components to be removed or modified by cutting, drilling or welding. The roller is capable of precise adjustment both horizontally and vertically relative to the conveyor to ensure levelness and accuracy without the use of tools.
US08063296B2
An Apparatus for Percussive Harmonic Musical Synthesis (APHAMS) which facilitates state-of-the-art musical expression, through generation of melodic sound, bearing well defined tone and note pitch, by the striking of uniquely configured multiple note activitation trigger mechanism surfaces, termed muzi-pads, with an appropriately sized mallet, stick, or other such similar playing implement, for the generation of a desired note, by a given MIDI device and which provides an enhanced emulation of the traditional tenor steelpan, in its interface with the player.
US08063294B1
A combining housing has first, second and third connectors. A music player has a first line adapted to be coupled to the first connector. A special effects box has a second line adapted to be coupled to the second connector. Earphones have a third line adapted to be coupled to the third connector. A musical instrument has a supplemental line adapted to be coupled to the special effects box. Positive, negative and ground wires are within each of the lines and continue within the combining housing. An electrical assembly includes the positive, negative and ground wires. The positive lines are coupled together within the combining housing forming a first junction. The negative wires are coupled together within the combining housing forming a second junction. The ground wires are coupled together within the housing forming a third junction.
US08063291B2
The disclosure of the present invention contemplates that provision is made for the guitar case to be supported from its bottom end by a foldable stand so that the case can be inclined upwardly at an angle relative to the horizontal, such as a floor surface. A guitar, when removed from the guitar case can then be suspended or hung from a hanger provided on the guitar case. The guitar is thereby oriented to be suspended substantially vertically, relative to the ground, and the bottom of the guitar is spaced from the ground or floor surface.
US08063285B1
A novel maize variety designated X7H211 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing maize variety X7H211 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X7H211 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X7H211, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X7H211. This invention further relates to methods for producing maize varieties derived from maize variety X7H211.
US08063283B1
A soybean cultivar designated 96462908 is disclosed. The invention relates to the seeds of soybean cultivar 96462908, to the plants of soybean 96462908, to plant parts of soybean cultivar 96462908, and to methods for producing a soybean plant produced by crossing soybean cultivar 96462908 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety 96462908, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 96462908, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar 96462908 with another soybean cultivar.
US08063280B2
A soybean cultivar designated 8012419 is disclosed. The invention relates to the seeds of soybean cultivar 8012419, to the plants of soybean 8012419, to plant parts of soybean cultivar 8012419, and to methods for producing a soybean plant produced by crossing soybean cultivar 8012419 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety 8012419, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 8012419, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar 8012419 with another soybean cultivar.
US08063275B2
A soybean cultivar designated 8249120 is disclosed. The invention relates to the seeds of soybean cultivar 8249120, to the plants of soybean 8249120, to plant parts of soybean cultivar 8249120 and to methods for producing a soybean plant produced by crossing soybean cultivar 8249120 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars or breeding cultivars and plant parts derived from soybean variety 8249120, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 8249120 and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants and plant parts produced by crossing the cultivar 8249120 with another soybean cultivar.
US08063267B2
The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
US08063265B2
A hydrogel having a floatability where from 40% to 90% of a solution and/or suspension to be thickened are thickened starting from the surface of the liquid and the rest of the solution and/or suspension to be thickened is thickened starting from the bottom of the container, a process for preparing the hydrogel and also its use for absorbing blood and/or body fluids, especially in hygiene articles, or for thickening aqueous solutions and/or suspensions, especially for thickening medical wastes.
US08063263B2
Devices, bandages, kits and methods are described that can control or regulate the mechanical environment of a wound to ameliorate scar and/or keloid formation. The mechanical environment of a wound includes stress, strain, and any combination of stress and strain. The control of a wound's mechanical environment can be active, passive, dynamic, or static. The devices are configured to be removably secured to a skin surface in proximity to the wound site and shield the wound from endogenous and/or exogenous stress.
US08063262B2
A hazardous gas abatement system decontaminates an exit gas stream containing global warming gases using an electrical heater and a water scrubber. One or more top flow hazardous gas inlets introduce hazardous gases into a heater compartment. Air or oxygen is introduced into a separate chamber for dynamic oxidation and cooling. The streams are mixed and oxygen reacts with the hazardous gases. Solid particulates from the reaction are removed by a filter in a quick disconnect bottom chamber. Filtered exhaust gases flow upward in an exhaust chamber surrounding the heater compartment and through water spray scrubbers. A cleaning ring mounted on an eccentric rod cleans particles from the outside of the internal heater, and the inside of the external heater. An air cylinder drives the eccentric rod and cleaning ring down and up between the heaters and stores the ring above the gas inlets.
US08063261B2
A system for dehydrogenating a C3 or C4 hydrocarbon feed stream containing a first and second layer of catalysts placed in the hydrocarbon feed stream, wherein the feed stream first passes through the first layer and then the second layer of catalysts and wherein the catalysts of the first layer contain from about 50 to about 90 percent by weight of an eta-alumina carrier, from about 10 to about 50 percent by weight of chromia and from about 0.1 to about 5 percent by weight of a zirconium compound and wherein the catalysts of the second layer of catalysts contain from about 50 to about 90 percent by weight of an eta-alumina carrier and from about 10 to about 50 percent by weight of chromia, without an added zirconium compound.
US08063257B2
A method for preparing 2,3,3,3-tetrafluoropropene comprising contacting a reactant comprising CCl2═CFCH2Cl with a fluorinating agent, such as HF, under conditions effective to produce a reaction product comprising CF3CF═CH2.
US08063256B2
The invention provides a process for the preparation of an alkylene glycol from an alkene. The gas composition from an alkylene oxide reactor is contacted with lean absorbent in an alkylene oxide absorber in the presence of one or more catalysts that promote carboxylation. The lean absorbent comprises at least 50 wt % alkylene carbonate and less than 10 wt % water and is supplied to the alkylene oxide absorber at a temperature greater than 60° C. Alkylene oxide reacts with carbon dioxide in the absorber, forming alkylene carbonate, and fat absorbent comprising alkylene carbonate is withdrawn from the absorber. A portion of the fat absorbent is supplied to one or more hydrolysis reactors, wherein alkylene carbonate reacts with water in the presence of one or more hydrolysis catalysts. The product stream from the hydrolysis reactor is dehydrated and purified.
US08063251B2
A process for the preparation of optically pure R (−) salbutamol of formula (6) and its pharmaceutically acceptable salts by using a (+) 4-nitro tartranilic acid as the resolving agent and a binary solvent system comprising alkyl acetate and C1 to C4 branched or normal chain alcohol for dissolution of the racemic mixture and resolving agent and purification of the 4-nitro tartranilic acid salt of R (−) salbutamol. 4-nitro tartranilic acid salt of R (−) salbutamol is converted into formic acid salt of R (−) 4-benzyl salbutamol followed by basification and debenzylation to form optically pure R (−) salbutamol. Optically pure (R)-salbutamol is obtained in good yield and high purity. The optically pure R (−) salbutamol is optionally converted into pharmaceutically acceptable salts.
US08063240B2
A prostaglandin analog with selectivity to EP receptors and demonstrating EP agonist activity that may be used to expand hematopoietic stem cell populations or to treat or prevent influenza, bone fracture, bone disease, glaucoma, ocular hypertension, dysmenorrhoea, pre-term labor, immune disorders, osteoporosis, asthma, allergy, male sexual dysfunction, female sexual dysfunction, periodontal disease, gastric ulcer, renal disease, or other EP receptor-mediated conditions.
US08063237B2
A process for combining a polythiol reactant and an alkenyl silane reactant to form a polysulfide polysilane. The reactants are combined in a thiol-ene addition process driven by UV radiation. The polysulfide polysilane is then hydrolyzed and may be combined with other hydrolyzed compounds. For coatings, the polysulfide polysilane is hydrolyzed and may optionally be combined with nanoparticles. For bulk materials, the polysulfide polysilane is hydrolyzed, concentrated, and heated to form a high refractive index material which can be used to form optical articles such as lenses.
US08063235B2
Method for improving the performance of a preparative batchwise Super Critical Fluid Chromatographic separation for the recovery of a target fatty acid or derivative thereof, or of a group of target fatty acids or of derivatives thereof from a mixture, characterized in that the said Super Critical Fluid Chromatographic separation employs a chromatographic column charged with a stationary phase chosen from the group consisting of aluminium oxide or aluminium oxides, titanium oxide or titanium oxides, silica gel or silica gels, amino propyl modified silica gels, diol modified silica gels, phenyl modified silica gels and “reversed phase” phases, the former in turn chosen from the group consisting of RP18, RP8 and RP3, and in that the said Super Critical Fluid Chromatographic Separation further employs a mobile phase chosen from the group consisting of ethylene, propane, ammonia, dinitrogen dioxide and CO2, wherein in the said method, during the run of the said mixture on the chromatographic column, a pressure and/or temperature gradient is applied to the chromatographic column during the elution of the target fatty acid or derivative thereof.
US08063230B1
The present invention relates to tris(N-aryl-benzimidazole)benzene compounds of the formula: where R1-R6, Ar, m, n, p, q, r, and s are defined in the specification. Also provided are compositions comprising tris(N-aryl-benzimidazole)benzene compounds. The invention also relates to use of such compounds in electronic devices.
US08063228B1
Methods of preparing heterocyclic triazolium-based nitrate salts by a streamlined process are provided. Such salts offer energetic performance as well as pharmaceutical potential.
US08063224B2
Azacycloalkane derivatives of structural formula I are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.
US08063223B2
Disclosed is a benzylpiperizine compound represented by formula (1) or a pharmaceutically acceptable salt thereof, which is useful as a medicinal agent such as an antidepressant agent. (In the formula (1), R1 represents a hydrogen atom or a methyl group; R2 is a group bound in a p- or m-position relative to a methylene group and represents a chlorine atom bound in a p-position, a bromine atom bound in a p-position, a methyl group bound in a p-position, a chlorine atom bound in a m-position or a bromine atom bound to in a m-position; X represents a methylene or an oxygen atom; and n represents an integer of 1 to 3.)
US08063222B2
The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein R1, X, Z, R2, X1, Ar, n, R3 and R4 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR8 and accordingly are useful for the treatment of a variety of inflammatory and allergic disorders.
US08063219B2
The invention concerns nitrogenated heterocyclic compounds, their preparation and use as antibacterial drugs, compounds of general formula (I) wherein R1 represents a (CH2)n-NHR2 or (CH2)n-NHR radical, where R is a (C1-C6) alkyl and n is equal to 1 or 2; R2 represents a hydrogen atom; R3 and R4 together form an aromatic nitrogenated heterocycle with 5 apexes with 1, 2 or 3 nitrogen atoms optionally substituted by one or several R′ groups, R′ being selected in the group composed of a hydrogen atom and alkyl radicals with 1 to 6 carbon atoms; in free form, as zwitterions, and in the form of salts of pharmaceutically acceptable inorganic or organic bases and acids.
US08063217B2
A process for preparation of Methyl-(+)-(S)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid methyl ester or salts thereof [clopidogrel or salts thereof of Formula (I)] having higher chiral purity and products thereof is provided. A process for purification of the compound prepared is also provided to enhance its efficacy by enhancing its optical rotation and chiral purity. In Formula (I), R is selected from a group comprising alkyl, alkoxy, hydroxy, amine etc., and R1 is selected from the group comprising C1-4 alkyl, C1-4 alkoxy, hydroxy, nitro & halogen. The particular salt of interest of the present invention is the hydrogen sulfate of compound of the Formula (I), wherein R and R1 are —OCH3 and chloro-group at position 2 respectively.
US08063215B2
Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
US08063213B2
An improved process for the manufacture of (E)-7-[4-(4-flurophenyl)-6-isopropyl-2-[methyl(methylsulfony)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium salt, Formula (1), which is useful for the production of a pharmaceutical useful in the treatment of, inter alia, hypercholesterolemia, hyperlipoproteinemia and atherosclerosis, is described.
US08063211B2
The present invention provides rosuvastatin and intermediates thereof having a low level of alkylether impurity and processes for the preparation thereof.
US08063201B2
Carbohydrates having functional groups, such as carboxylic acid groups and methods of making such carbohydrates.
US08063198B2
The present invention relates to processes and reagents for oligonucleotide synthesis and purification. One aspect of the present invention relates to compounds useful for activating phosphoramidites in oligonucleotide synthesis. Another aspect of the present invention relates to a method of preparing oligonucleotides via the phosphoramidite method using an activator of the invention. Another aspect of the present invention relates to sulfur-transfer agents. In a preferred embodiment, the sulfur-transfer agent is a 3-amino-1,2,4-dithiazolidine-5-one. Another aspect of the present invention relates to a method of preparing a phosphorothioate by treating a phosphite with a sulfur-transfer reagent of the invention. In a preferred embodiment, the sulfur-transfer agent is a 3-amino-1,2,4-dithiazolidine-5-one. Another aspect of the present invention relates to compounds that scavenge acrylonitrile produced during the deprotection of phosphate groups bearing ethylnitrile protecting groups. In a preferred embodiment, the acrylonitrile scavenger is a polymer-bound thiol. Another aspect of the present invention relates to agents used to oxidize a phosphite to a phosphate. In a preferred embodiment, the oxidizing agent is sodium chlorite, chloroamine, or pyridine-N-oxide. Another aspect of the present invention relates to methods of purifying an oligonucleotide by annealing a first single-stranded oligonucleotide and second single-stranded oligonucleotide to form a double-stranded oligonucleotide; and subjecting the double-stranded oligonucleotide to chromatographic purification. In a preferred embodiment, the chromatographic purification is high-performance liquid chromatography.
US08063196B2
The invention provides a set of highly orthogonal six-code universal sequences for use in bDNA singleplex and multiplex nucleic acid hybridization assays. The six-code orthogonal sequences do not cross-hybridize and thus, minimize or eliminate the 3-mer cross-hybridization inherent in the second and third generation bDNA assays. The highly orthogonal universal sequences may be used in singleplex or multiplex bDNA assays quantitatively and qualitatively to determine mRNA levels in a sample; to screen for and genotype targets, such as viruses, that are present in low volumes in a sample; to screen for and genotype SNPs; and to measure changes in the amount of a gene in a sample such as when gene amplifications or deletions occur. The highly orthogonal universal sequences may also be used as universal capture probes to selectively bind assay components in a way that facilitates their further analysis.
US08063195B2
NS4B is one of the non-structural proteins of classical swine fever virus. By using functional genetics, we have discovered, in the predicted amino acid sequence of NS4B of CSFV strain Brescia, a motif that resembles those found in the toll-like receptor (TLR) proteins, a group of host cell proteins involved in the development of anti-viral mechanisms. We have located the TLR motif in two groups of amino acid triplets at amino acid positions 2531-3 (residues IYK) and 2566-8 (residues VGI) of the CSFV NS4B glycoprotein. We have constructed a recombinant CSFV (derived from an infectious clone containing the genetic information of the highly virulent strain Brescia) containing amino acid substitutions in the three amino acid residues at positions 2566, 2567 and 2568, where the VGI triplet has been replaced by an AAA triplet inside the NS4B glycoprotein. The obtained virus, named NS4B-VGIv, was completely attenuated in swine, showing a limited ability in spreading during the infection in vivo. Although attenuated, NS4B-VGIv efficiently protected swine from challenge with virulent BICv at 3 and 28 days post-infection.
US08063194B2
The present invention relates to a polypeptide which has a novel specific arabinose transporter function as well as to nucleic acids coding therefore. The invention further relates to host cells, in particular modified yeast strains which contain the coding nucleic acids and express the polypeptide and functionally integrate it into the plasma membrane and are thus able to absorb L-arabinose. When using modified host cells which express additional proteins of the arabinose metabolic pathway, arabinose can be fermented by these cells, in particular into ethanol. The present invention is therefore relevant, inter alia, in connection with the production of biochemicals from biomass, such as bioethanol for example.
US08063190B2
Compounds that are readily dissociable conjugates of a multiplicity of biologically active molecules are formed by bonding to each biologically active molecule one or more oligonucleotide chains selected to comprise partially complementary sequences that form duplexes with other such oligonucleotides attached to other biologically active molecules. The claimed conjugates and methods for preparing the conjugates of the invention can be used to link two or more biologically active molecules, as well as conjugating a multiplicity of biologically active molecules. In alternative embodiments, conjugates comprising such covalently linked oligonucleotides linked by one or a multiplicity of “bridging” oligonucleotides are provided. Methods for making these different types of conjugates and for using such conjugates for research, immunoassay, medical and technical applications are also provided by the invention. The disclosed methods provide for the formation of intermolecular links which are hydrophilic, of relatively low toxicity and antigenicity, are as flexible and extensible as desired, and are stable yet dissociable. Both the components and the conjugates of the invention can be isolated and purified with relative ease compared with other intermediates and conjugates.
US08063183B2
In certain embodiments, this present invention provides polypeptide compositions, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
US08063178B2
Trp cage binding domains polypeptides are disclosed. The Trp cage binding domains have the generic formulae of SEQ ID NO: 2, 7, 10 or 11. They can be efficiently produced and screened using phage display technology.
US08063174B2
A PBI compound includes imidazole nitrogens at least a portion of which are substituted with a moiety containing a carbonyl group, the substituted imidazole nitrogens being bonded to carbon of the carbonyl group. At least 85% of the nitrogens may be substituted. The carbonyl-containing moiety may include RCO—, where R is alkoxy or haloalkyl. The PBI compound may exhibit a first temperature marking an onset of weight loss corresponding to reversion of the substituted PBI that is less than a second temperature marking an onset of decomposition of an otherwise identical PBI compound without the substituted moiety. The PBI compound may be included in separatory media. A substituted PBI synthesis method may include providing a parent PBI in a less than 5 wt % solvent solution. Substituting may use more than 5 equivalents in relation to the imidazole nitrogens to be substituted.
US08063171B2
A three dimensional structure fabricated from a self-healing polymeric material, comprising poly(ester amides) obtained from ethylene glycol, azelaic acid and 1,1-aminoundecanoic acid, wherein polymeric material has a melt index above 2.5 g/10 min. as determined by ASTM D1238 at 190° C. and 2.16kg, impact resistance and ductility sufficient to resist cracking and brittle fracture upon impact by a 9 mm bullet fired at a temperature of about 29° C. at subsonic speed in a range from about 800 feet/sec to about 1000 feet/sec. It has been determined that the important factors necessary for self-healing behavior of polymers include sufficient impact strength, control of the degree of crystallinity, low melting point and the ability to instantly melt at impacted area.
US08063170B2
Radiation curable compositions comprising at least one radiation curable oligomer obtained from the reaction of one or more carboxyl functional polyester (a) having a glass transition temperature TG and/or melting temperature Tm of less than 30° C., with (b1) one or more (meth)acrylated mono-epoxide, and/or (b2) one or more polyepoxide and one or more α, β unsaturated carboxylic acid.
US08063158B2
There are disclosed polymerization processes and associated apparatuses. The polymerization processes involve both making a polymeric material in a fluidized bed reactor having a feed distributor and catching a spitwad with a spitwad catcher, and the apparatuses are those corresponding to such processes.
US08063150B2
Crosslinkable perfluoroelastomer compositions having low metal content and low compression set when crosslinked, and processes for producing the same, are provided. Compositions comprising terpolymers of TFE, PAVE, and CNVE having a metal content of less than 3000 ppb may be formed into high purity transparent perfluoroelastomer parts.
US08063148B2
The present invention relates to a polyolefin composition comprising an olefin homo- or copolymer (A) in an amount of 90 wt. % or more, and an olefin homo- or copolymer (B) comprising hydrolysable silicon-containing groups, wherein olefin homo- or copolymer (B) is present in the composition in an amount of from 0.01 to 2 wt. %.
US08063136B2
The novel process provides latices of homo- and copolymers of chloroprene and of one or more further copolymerizable monomers at a higher reaction rate and hence in an improved space-time yield. The latices obtained have a high gel content, distinctly lower levels of by-products, in particular of chloroprene dimer, than prior art products, and are useful, if appropriate in concentrated form, for a wide variety of applications.
US08063129B2
Use of a composition consisting essentially of a mixture of aliphatic esters as a slip agent in a polyester polymer, said composition comprising at least two esters selected from the group comprising: Myristyl myristate, Myristyl palmitate, palmityl myristate, palmityl palmitate, palmityl stearate, stearyl myristate, stearyl palmitate, stearyl stearate, stearyl arachidate and stearyl behenate.
US08063124B2
The use of oxidizable phosphorus or phosphorous stabilizers, such as the phosphites, to reduce the color formation of the ionomeric polyester compositions is disclosed.
US08063123B2
The invention relates to phosphorus-containing mixtures containing compounds of the formula RO—PO(A)-CH2—CH2—CO2H and (I) HO—PO(A)-CH2—CH2—CO2R (II) in which A is C1-C18-alkyl, C6-C18-alkylaryl, C6-C18-aralkyl or aryl, R is (D,E)C═C(B, R5) or H B, D, E are identical or different and are each H or C1-C18-alkyl R5 is —CO-alkoxy, a process for their preparation and their use.
US08063114B2
A chiral inorganic mesoporous material characterized by having a chiral twisted structure and being mesoporous; a process for producing the material; and a method of using the material. The process for inorganic mesoporous material production is a method in which one or more polymerizable inorganic monomers selected from the group consisting of polymerizable inorganic monomers and polymerizable inorganic monomers having a functional group capable of having a charge are polymerized in the presence of a solvent using as a template a self-assembly of a chiral surfactant such as an N-(higher alkanoyl)amino acid salt. Examples of the use of the inorganic mesoporous material include the separation of racemates and reaction fields for asymmetric syntheses.
US08063111B2
Anion-conducing polymers and membranes with enhanced stability to aqueous alkali include a polymer backbone with attached sulfonium, phosphazenium, phosphazene, and guanidinium residues. Compositions also with enhanced stability to aqueous alkali include a support embedded with sulfonium, phosphazenium, and guanidinium salts.
US08063110B2
Process for the conversion of carbon oxide(s) and hydrogen-containing feedstocks to oxygen containing hydrocarbon compounds in the presence of a particulate rhodium-based catalyst, by reacting carbon oxide(s) and hydrogen in the presence of a particulate rhodium-based catalyst in a conversion reactor to form oxygen containing hydrocarbon compounds. At least one paraffinic aliphatic monohydric alcohol of the formula R-OH where R is a hydrocarbon radical having 1 or 3 to 5 carbon atoms is/are separated from the other oxygenates produced in the conversion reactor, and is/are then sent back to the conversion reactor.
US08063109B2
Formulations are provided for parenteral administration of (amino substituted (e)-2,6-dialkoxystyryl 4-substituted benzylsulfones and the sodium and potassium salts thereof for the prevention and/or treatment of conditions mediated by abnormal cell proliferation. Composition for parenteral administration are provided which comprise an effective amount of compound of formula I or a compound of formula IIa and at least about 50% by weight of at least one water soluble polymer selected from the group consisting essentially of polyethylene glycol (PEG), poly-oxyethylene, poly-oxyethylene-poly-oxypropylene copolymers, polyglycerol, polyvinylalcohol, polyvinylpyrrolidone (PVP), polyvinylpyridine N-oxide, copolymer of vinylpyridine N-oxide and vinylpyridine.
US08063104B2
Compounds of formula (I) have been found to be useful as inhibitors of DDAH. The present invention thus provides the use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in the treatment of a disease whose pathology is affected by DDAH
US08063094B2
Heterocyclic compounds which are inhibitors of Mitrogen-Activated Protein Kinase-Activated Protein Kinase-2 (MAPKAP-K2) as described, in addition to their use in the treatment of cytokine mediated diseases.
US08063091B2
Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
US08063079B2
A compound of the formula: and pharmaceutical compositions for the treatment of diabetes.
US08063077B2
The present invention is directed to compounds of formula (I) and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to intermediates used in making such compounds, pharmaceutical compositions containing such a compound, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
US08063072B2
Compounds having the formula I wherein R1, R2, R3, R4, and R5 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
US08063071B2
The invention is directed to novel indole carboxamide derivatives. Specifically, the invention is directed to compounds according to formula I: where R1, R2, R3, U and V are defined below and to pharmaceutically acceptable salts thereof. The compounds of the invention are inhibitors of IKK2 and can be useful in the treatment of disorders associated with inappropriate IKK2 (also known as IKKβ) activity, such as rheumatoid arthritis, asthma, and COPD (chronic obstructive pulmonary disease). Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting IKK2 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.
US08063063B2
The invention provides novel compositions comprising Imidazopyridine compounds. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an)other agent(s).
US08063060B2
The invention features derivatives of R(−)-11-hydroxyaporphines and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith.
US08063058B2
The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
US08063053B2
The invention relates to 1-(arylsulfonyl)-4-(piperazin-1-yl)-1H-benzimidazole compounds of the Formula I: or a tautomer, stereoisomer, or pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
US08063047B2
The invention relates to novel chemical compounds of Formula I compositions and methods of using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
US08063046B2
Compounds having high angiogenesis inhibiting activity useful as agents for effective treatment and prevention of diseases involving pathologic angiogenesis, e.g. cancer and cancer metastasis, are of formula (II), where A1 is C—X1 or N; Q1 is -A2=A3-, or a heteroatom selected from —O—, —S—, and —N(R10)—; Q2 is -A4=A5-, or a heteroatom selected from —O—, —S—, and —N(R10)—; provided that Q1 and Q2 are not heteroatoms at the same time; A2 is C—X2 or N, A3 is C—X3 or N, A4 is C—X4 or N, and A5 is C—X5 or N; Y is C1-6alkyl, C3-9cycloalkyl, C2-7alkenyl, C2-7alkynyl, C1-6alkoxy, C2-7alkenyloxy, C2-7alkynyloxy, or C1-6alkylthio; Z is a hydrogen atom, hydroxy, C1-6alkyl, C3-9 cycloalkyl, or —NR1R2; and L is selected from the formula:
US08063027B2
A method of preventing or reducing the incidence of post-operative adhesions in or associated with a body cavity, which comprises introducing into the body cavity a composition containing an aqueous solution or suspension or gel formulation containing the polysaccharide dextrin.
US08063020B2
A method for treating conditions related to lack of blood supply with a lipid based resuscitation fluid is disclosed. The resuscitation fluid contains a lipid component and an aqueous carrier. The lipid component forms an emulsion with the aqueous carrier. The resuscitation fluid can be used to increase the blood pressure and to carry oxygen to tissues. The resuscitation fluid can also be used for preserving the biological integrity of donor organs for transplantation.
US08063019B2
The present invention relates to the use of Stefin A as a scaffold protein for the display of inserted peptides, particularly wherein the Stefin A is a human Stefin A. Several mutations are advantageously made in the wild type stefin A sequence to improve it as a scaffold; preferably the Stefin A comprises a heterologous peptide insertion at the Leu 73 site. Furthermore, preferably the scaffold protein comprises a V48D mutation; preferably the scaffold protein comprises a G4W mutation. Preferably the scaffold comprises Leu73, V48D and G4W mutations. The invention also relates to the scaffold proteins themselves, in particular a stefin A polypeptide having the Leu73, V48D and G4W mutations, such as shown as SEQ ID NO: 1. The invention also relates to a method for identifying binding proteins and to peptide A (RLNKPLPSLPV) and its use in treating yeast infections.
US08063011B2
An in vitro method for predicting the onset of type 1 diabetes (T1 D) in a subject, comprises the steps of: (a) measuring the concentration of at least one amino acid, amino acid derivative or amino acid metabolite in a biological sample taken from the subject; (b) determining the subject's HLA genotype; (c) assigning the subject's genetic risk of developing T1 D on the basis of the subject's HLA genotype; (d) combining the information obtained in step (a) with the information in step (c); and (e) predicting the likelihood of onset of T1 D based upon the combination of step (d). The diagnostic method can be used to select target subjects for T1 D prophylactic treatment, and as part of a T1 D preventative treatment regime for neonates having a likelihood of developing childhood T1 D.
US08063010B2
A solid detergent composition is provided according to the invention. The solid detergent composition is a result of solidifying a detergent composition precursor. The detergent composition precursor includes at least about 20 wt. % hydratable alkaline component, at least about 5 wt. % surfactant component, and water in an amount sufficient to allow the composition to solidify. Methods for manufacturing and using the solid detergent composition are provided.
US08063005B2
A non-aqueous cleansing formulation having cleansing, moisturizing and/or exfoliating properties includes an oil phase and a natural surfactant derived from legumes and/or grains. The oil phase can include an oil component and a thickening agent. The natural surfactant can be in the form of a particulate flour product derived from Vigna radiata, Vigna mungo, Glycine max, Cicer aerientinum, Vigna unguicalata, Pisum sativum, Phaseolus vulgaris, or combinations thereof, which is dispersed in the oil phase. The flour product suitably includes a high protein flour to emulsify the oil phase and provide improved cleansing action. Such non-aqueous cleansing formulation can be used as skin care products, hand cleansers, hair cleaners or general use cleansers. Advantageously, the cleansing formulations are free of synthetic soaps and/or synthetic surfactants.
US08063002B2
A solid lubricating composition having resin material is disposed between an outer ring and an inner ring of a ball bearing. As the resin material contained in the solid lubricating composition, resin material having a property of being solidified when the resin material in a fluid state is irradiated with an ultraviolet beam is used.
US08062993B2
The present invention relates to a developer mixture for a thermal recording material, which comprises a mixture of the first organic developer comprising a condensate or a condensed composition represented by the formula (I): wherein R is a lower alkyl group or an aralkyl group, n is an integer of 0 to 5, and X and Y are each a hydrogen atom, an alkyl group or an aryl group, and the second organic developer other than the first organic developer (except 2,2-bis(3-methyl-4-hydroxyphenyl)propane), a developer mixture for a thermal recording material, and a thermal recording material having a heat-coloring layer containing the developer mixture. Using the developer mixture for a thermal recording material of the present invention, a thermal recording material sufficiently satisfying the recent requirement for high sensitivity, and having superior preservation stability of color images and non-image areas can be realized.
US08062990B2
A pliable refractory metal carrier (46) may have coated thereon an anchor layer (47) to improve adherence to the carrier (46) of a catalytic coating (48). The conformable catalyst member (26, 82, 82′, 126, 226, 326) may be bent to conform to a curved or bent exhaust pipe (20, 220, 320) within which it is mounted. The pliable metal carrier may be in the form of a tube such as carrier (46) having perforations (54) formed therein, or it may be a metal strip (76) which is folded into accordion pleats (80) and has perforations (78) formed therein. The perforations (54, 78) serve to permit the passage of exhaust gas therethrough. A series of interior closures (58) and annular baffles (60) may be provided to import a serpentine flow path to gases flowed through an exhaust pipe (22) containing a conformable catalyst member (226) therein. A mounting member (68) may be supplied to fasten one end of the conformable catalyst member (226) to the discharge end of an exhaust pipe (220).
US08062989B2
Catalyst precursors comprising Mg, Cl, Ti, and OR groups that are in molar ratios defined by the formula MgClnTip(OR)(2−n)+4p in which n is from 0.3 to less than 1.7, p is lower than 0.6, the molar ratio (OR)/Cl is lower than 4 and R is C1-C15 hydrocarbon groups. The said precursor, just upon activation with organo-Al compounds, are able to advantageously polymerize ethylene and alpha olefins, and that upon reaction with halogenating compounds generate in high yields catalyst components with high polymerization activity particularly in the polymerization of propylene also in combination with 1,3-diethers.
US08062984B2
A method of fabricating an electronic device, the device including a plurality of layers on a substrate, the layers including an upper conductive layer and at least one patterned underlying layer between said conductive layer and said substrate. The method includes patterning said underlying layer, and patterning said upper conductive layer by laser ablation using a stepwise process in which successive areas of said upper conductive layer are ablated by successively applied laser patterns. The successively applied laser patterns overlap one another in an overlap region. The method further includes configuring a said laser pattern and said patterned underlying layer with respect to one another such that in a said overlap region said patterned underlying layer is substantially undamaged by said stepwise laser ablation.
US08062980B2
A method of fabricating a semiconductor device according to one embodiment includes: forming a core material on a workpiece; forming a coating film comprising an amorphous material so as to cover an upper surface and side faces of the core material; crystallizing the coating film by applying heat treatment; forming a sidewall mask by removing the crystallized coating film while leaving a portion thereof located on the side faces of the core material; removing the core material after forming the sidewall mask; and etching the workpiece using the sidewall mask as a mask after removing the core material.
US08062978B2
Crystalline aluminum oxide layers having increased energy band gap, charge trap memory devices including crystalline aluminum oxide layers and methods of manufacturing the same are provided. A method of forming an aluminum oxide layer having an increased energy band gap includes forming an amorphous aluminum oxide layer on a lower film, introducing hydrogen (H) or hydroxyl group (OH) into the amorphous aluminum oxide layer, and crystallizing the amorphous aluminum oxide layer including the H or OH.
US08062976B2
A method is for forming a vertical interconnection through a dielectric layer between upper and lower electrically conductive layers of an integrated circuit. The method includes forming an opening through the dielectric layer and placing a solidifiable electrically conductive filler into the opening via a printing technique. The solidifiable electrically conductive filler is solidified to thereby form a solidified electrically conducting filler in the opening. A metallization layer is formed over the dielectric layer and the solidified electrically conducting filler to thereby form the vertical interconnection through the dielectric layer between the upper and lower electrically conductive layers of the integrated circuit.
US08062957B2
The invention relates to a method for preparing a surface of a semiconductor substrate by oxidizing the surface of the semiconductor substrate to thereby transform the natural oxide into an artificial oxide and then removing the artificial oxide, in particular to obtain an oxide-free substrate surface.
US08062953B2
A method of making a semiconductor device is achieved in and over a semiconductor layer. A trench is formed adjacent to a first active area. The trench is filled with insulating material. A masking feature is formed over a center portion of the trench to expose a first side of the trench between a first side of the masking feature and the first active area. A step of etching into the first side of the trench leaves a first recess in the trench. A first epitaxial region is grown in the first recess to extend the first active area to include the first recess and thereby form an extended first active region.
US08062950B2
A semiconductor device has a semiconductor substrate, and a capacitor which is provided on the upper side of the semiconductor substrate and composed of a lower electrode, an upper electrode and a dielectric film, the dielectric film being placed in between the lower electrode and the upper electrode, the lower electrode including a noble metal film, and a plurality of conductive oxide films formed in an islands arrangement on the noble metal film.
US08062949B2
One aspect of the present subject matter relates to a method for forming a transistor. According to an embodiment of the method, a pillar of amorphous semiconductor material is formed on a crystalline substrate, and a solid phase epitaxy process is performed to crystallize the amorphous semiconductor material using the crystalline substrate to seed the crystalline growth. The pillar has a sublithographic thickness. A transistor body is formed in the crystallized semiconductor pillar between a first source/drain region and a second source/drain region. A surrounding gate insulator is formed around the semiconductor pillar, and a surrounding gate is formed around and separated from the semiconductor pillar by the surrounding gate insulator. Other aspects are provided herein.
US08062947B2
The present invention relates to a method of manufacturing a semiconductor device having a shared contact for connection between a source/drain region and a gate electrode. After formation of a gate electrode via a gate insulating film on a semiconductor substrate, a top surface of the substrate is covered with a cover film. After removal of the cover film from at least one of sidewall surface of the gate electrode and a part of the top surface of the substrate adjacent to the sidewall surface, a semiconductor layer is epitaxially grown on a top surface of an exposed substrate to electrically connect the substrate and the at least one sidewall surface of the gate electrode. Then, a source/drain region is formed in a top surface part of the substrate or the semiconductor layer using the gate electrode as a mask.
US08062939B2
A semiconductor storage element includes: a semiconductor layer constituted of a line pattern with a predetermined width formed on a substrate; a quantum dot forming an electric charge storage layer formed on the semiconductor layer through a first insulating film serving as a tunnel insulating film; an impurity diffusion layer formed in a surface layer of the semiconductor layer so as to sandwich the quantum dot therebetween; and a control electrode formed on the quantum dot through a second insulating film.
US08062931B2
In the preferred embodiments, a method to reduce gate leakage and dispersion of group III-nitride field effect devices covered with a thin in-situ SiN layer is provided. This can be obtained by introducing a second passivation layer on top of the in-situ SiN-layer, in combination with cleaning of the in-situ SiN before gate deposition and before deposition of the second passivation layer.
US08062918B2
This disclosure provides a method of fabricating a semiconductor device layer and associated memory cell structures. By performing a surface treatment process (such as ion bombardment) of a semiconductor device layer to create defects having a deliberate depth profile, one may create multistable memory cells having more consistent electrical parameters. For example, in a resistive-switching memory cell, one may obtain a tighter distribution of set and reset voltages and lower forming voltage, leading to improved device yield and reliability. In at least one embodiment, the depth profile is selected to modulate the type of defects and their influence on electrical properties of a bombarded metal oxide layer and to enhance uniform defect distribution.
US08062916B2
LED layers are grown over a sapphire substrate. Individual flip chip LEDs are formed by trenching or masked ion implantation. Modules containing a plurality of LEDs are diced and mounted on a submount wafer. A submount metal pattern or a metal pattern formed on the LEDs connects the LEDs in a module in series. The growth substrate is then removed, such as by laser lift-off. A semi-insulating layer is formed, prior to or after mounting, that mechanically connects the LEDs together. The semi-insulating layer may be formed by ion implantation of a layer between the substrate and the LED layers. PEC etching of the semi-insulating layer, exposed after substrate removal, may be performed by biasing the semi-insulating layer. The submount is then diced to create LED modules containing series-connected LEDs.
US08062913B2
A semiconductor structure is formed of nitrides of group III metals having wurtzite crystal structure and grown in vapor phase on a (0001) oriented semiconductor substrate. The structure comprises a bottom cladding layer, a top cladding layer, and a diffusion region positioned between the cladding layers for diffusing light propagating within the semiconductor structure. The diffuse region has refractive index different from those of the cladding layers and non-flat surfaces for providing light diffusing interfaces between the diffusion region and the cladding layers. According to the invention, the diffusion region comprises a plurality of diffusion layers, compositions and thicknesses of said diffusion layers having been chosen to avoid formation of strain-induced dislocations in the diffusion region, and adjacent diffusion layers having different refractive indices in order to further enhance the diffusion efficiency.
US08062911B2
A probe having a sufficient height is manufactured by selectively depositing, over the main surface of a wafer, a copper film in a region in which a metal film is to be formed and a region which will be outside an adhesion ring when a probe card is fabricated; forming the metal film, polyimide film, interconnect, another polyimide film, another interconnect and a further polyimide film; and then removing the wafer and copper film. According to the present invention, when probe testing is performed using a prober (thin film probe) having the probe formed in the above-described manner while utilizing the manufacturing technology of semiconductor integrated circuit devices, it is possible to prevent breakage of the prober and a wafer to be tested.
US08062910B1
A sample that is processed to remove a top layer, e.g., using chemical mechanical polishing or etching, is accurately measured using multiple models of the sample. The multiple models may be constrained based on a pre-processing measurement of the sample. By way of example, the multiple models of the sample may be linked in pairs, where one pair includes a model simulating the pre-processed sample and another model simulating the post-processed sample with a portion of the top layer remaining, i.e., under-processing. Another pair of linked models includes a model simulating the pre-processed sample and a model simulating the post-processing sample with the top layer removed, i.e., the correct amount of processing or over-processing. The underlying layers in the linked model pairs are constrained to have the same parameters. The modeling process may use a non-linear regression or libraries.
US08062903B2
Methods and devices are provided for overcoming detrimental diffusive effects in a sample liquid stream by forming segmented liquid bodies (e.g., droplets) from a sample liquid stream in an immiscible liquid stream. The liquid bodies are formed at the intersection of a channel providing the sample liquid stream and a channel providing the immiscible liquid stream. The formed liquid bodies compartmentalize the portion of the sample liquid stream from which the liquid bodies are formed, thus minimizing the detrimental effects of diffusion that occur in a continuous liquid stream.
US08062900B2
A microplate for use within an interrogation system and a method of using the microplate are disclosed. The microplate contains within the bottom of each well, an optical waveguide grating based sensor. Approximate to each sensor is a mask having an aperture of predetermined size. The aperture regulates the light that enters and exits the sensor upon successive scans and ensures repeatable readings from the sensor. In an extended embodiment, a method of detection is disclosed that utilizes a launch and receive system while employing the aforementioned microplate.
US08062897B2
The present invention relates to a method for detecting one or more nascent RNAs in a tissue sample using FISH. In the method, a plurality of probes (8 to 82) may be used to detect a single species of nascent RNA. Further, a plurality of nascent RNA species may be detected simultaneously using between 8 and 82 probes for each nascent RNA. The invention comprises, in addition, methods of preparing a sample for nascent RNA detection by reducing autofluorescence of the tissue sample. These techniques may be synergistically combined to achieve significantly improved results.
US08062893B2
The present invention provides a sensor for detecting mercury, comprising: a first polynucleotide, comprising a first region, and a second region, a second polynucleotide, a third polynucleotide, a fluorophore, and a quencher, wherein the third polynucleotide is optionally linked to the second region; the fluorophore is linked to the first polynucleotide and the quencher is linked to the second polynucleotide, or the fluorophore is linked to the second polynucleotide and the quencher is linked to the first polynucleotide; the first region and the second region hybridize to the second polynucleotide; and the second region binds to the third polynucleotide in the presence of Hg2+ ions.
US08062887B2
The present invention provides a monoclonal antibody recognizing modification after translation of p53 in a manner specific to a modification site, an antibody microarray comprising the antibody immobilized on a substrate, etc. Disclosed is a monoclonal antibody which reacts specifically with a peptide consisting of an amino acid sequence of at least 6 consecutive amino acids containing a predetermined amino acid residue of the amino acid sequence represented by SEQ ID NO: 1, wherein the amino acid residue is phosphorylated or acetylated, or with a peptide having one to several arbitrary amino acids added to the above peptide, but does not react with the above peptide which is not phosphorylated or acetylated.
US08062872B2
Embodiments described include methods for maintaining the pH and alkalinity during industrial fermentation processes are described that foster optimal microorganism activities throughout the duration of the fermentation process. Magnesium based buffering agents having sufficient buffering capacity and applied at sufficient concentration levels required to neutralize the acidic content of fermentation fluids during the fermentation process cycle are detailed. These magnesium based buffering agents control fermenter processes without causing extreme pH swings to maximize the production of desired fermentation products.
US08062867B2
The invention provides a rabbit-derived immortal B-lymphocyte capable of fusion with a rabbit splenocyte to produce a hybrid cell that produces an antibody. The immortal B-lymphocyte does not detectably express endogenous immunoglobulin heavy chain and may contain, in certain embodiments, an altered immunoglobulin heavy chain-encoding gene. A hybridoma resulting from fusion between the subject immortal B-lymphocyte and a rabbit antibody-producing cell is provided, as is a method of using that hybridoma to produce an antibody. The subject invention finds use in a variety of different diagnostic, therapeutic and research applications.
US08062861B2
To preprocess a tissue sample, a first permeable mesh membrane is tautly stretched out over the tissue sample and overlaid on top of a flat surface. This covering sandwiches and secures the tissue sample in between the first permeable mesh membrane and the flat surface. If it is desired to reinforce the mechanical strength of the first permeable mesh membrane, a second permeable mesh membrane can be tautly stretched out and overlaid on top of the sandwich. Alternatively, the second permeable mesh membrane can be attached onto a third component, such as a disposable solvent resistant frame, to create a framed mesh. Thereafter, the first permeable mesh membrane may be attached to the framed mesh to create a compound framed mesh. The tissue sample may then be sandwiched and secured in between the compound framed mesh and the flat surface. To retain and flatten the tissue sample, gentle pressure may be uniformly applied.
US08062856B2
The present invention provides systems, methods, screens, reagents and kits for optical system analysis of cells to rapidly determine the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large numbers of compounds for those that specifically affect neurite outgrowth.
US08062853B2
The present invention is directed to methods for providing a polyelectrolyte multilayer film at a liquid-liquid interface. Such methods include steps of sequentially-depositing layers of cationic and anionic polyelectrolytes at a liquid-liquid interface that is formed between immiscible first and second liquids whereby a polyelectrolyte multilayer film is provided at the liquid-liquid interface. In certain preferred embodiments, the first liquid is an aqueous solution and the second liquid is a liquid crystal. In alternative embodiments, the first liquid is an aqueous solution and the second liquid is an oil. The invention further encompasses polyelectrolyte multilayer films provided by the disclosed methods as well as applications utilizing such materials.
US08062852B2
Disclosed herein are methods of treatment of autoimmune diseases such as systemic lupus erythematosus (SLE) as well as clinical assays for detection of autoimmune disease activity in patients utilizing the involving a PD1 ligand.
US08062841B2
Method and device to collect multiplex data simultaneously in analyte detection and analyze the data by experimentally trained software (machine-learning) is disclosed. Various ways (magnetic particles and microcoils) are disclosed to collect multiple reporter (tag) signals. Multiplex detection can increase the biomolecule analysis efficiency by using small sample size and saving assay reagents and time. Machine learning and data analysis schemes are also disclosed. Multiple affinity binding partners, each labeled by a unique reporter, are contacted with a sample and a single spectrum is taken to detect multiple reporter signals. The spectrum is deconvoluted by experimentally trained software to identify multiple analytes.
US08062840B2
The present invention provides a transgenic corn event MON89034, and cells, seeds, and plants comprising DNA diagnostic for the corn event. The invention also provides compositions comprising nucleotide sequences that are diagnostic for said corn event in a sample, methods for detecting the presence of said corn event nucleotide sequences in a sample, probes and primers for use in detecting nucleotide sequences that are diagnostic for the presence of said corn event in a sample, growing the seeds of such corn event into corn plants, and breeding to produce corn plants comprising DNA diagnostic for the corn event.
US08062836B2
The present invention relates to a method for manufacturing an optical filter for a stereoscopic image display device, which forms an alignment layer having different orientating directions along a fine region via a one-time continuous photo orientation process. The method comprising: forming a polymer layer on a substrate; a photo-orienting step comprising positioning a patterned mask above the polymer layer, the patterned mask having alternating light transmission regions and light shield regions arranged in both horizontal and a vertical directions to selectively transmit different polarized light, positioning a polarizer above the patterned mask where the polarizer has two distinguishable regions that transmit different polarized light, and downwardly irradiating UV light onto the polymer layer from above the polarizer, thereby forming an alignment layer having different orientating directions in fine regions of the polymer layer; and forming a retardation layer on the orientation layer. The alignment layer in which the fine regions with different orientating directions are formed alternately and continuously is obtained via a one-time continuous photo-orientation process. Therefore, the photo-orientation process and the method for manufacturing the optical filter are simplified in comparison with the conventional art. As a result, the process yield and productivity in the manufacturing of an optical filter for a 3D image display device are improved.
US08062835B2
A method of manufacturing a master plate includes the steps of forming a photoresist film on a substrate, disposing a photomask having a plurality of island radiation shields on the photoresist film followed by integrating the photomask and the photoresist film, applying light from a light source to the photoresist film through the photomask for selectively exposing the photoresist film, and developing the photoresist film to form a master plate, in which the method includes irradiating the photoresist film with the light from plural directions through the photomask to selectively expose the photoresist film from the respective directions.
US08062826B2
A positive resist composition includes: (A) a resin capable of increasing the solubility in an alkali developing solution by the action of an acid, including: (a1) a repeating unit selected from repeating units represented by specific formulae (a1-1) to (a1-3); (a2) a repeating unit represented by a specific formula (a2); and (a3) a repeating unit selected from repeating units represented by specific formulae (a3-1) to (a3-4); (B) a compound capable of generating an acid upon irradiation with actinic ray or radiation, (C) a resin including: at least one of a fluorine atom and a silicon atom; and a group selected from specific groups (x) to (z):(x) an alkali-soluble group, (y) a group capable of decomposing by the action of an alkali developing solution to increase the solubility in the alkali developing solution, and (z) a group capable of decomposing by the action of an acid; and (D) a solvent.
US08062818B2
An electrophotographic toner for electrostatic image development which is capable of obtaining a high chroma full-color image exhibiting clear color without color contamination and excellent light stability is disclosed, comprising a resin and a colorant, wherein the colorant comprises a pigment of C.I. Pigment Blue 76. There are also disclosed a full-color toner kit and an image forming method by use of the toner.
US08062816B2
A photoconductor that includes, for example, a substrate; a first layer like a ground plane layer; an undercoat layer thereover wherein the undercoat layer contains an aminosilane and a phosphonate; a photogenerating layer; and at least one charge transport layer.
US08062814B2
Photolithographic apparatus, systems, and methods that make use of optical compensation devices are disclosed. In various embodiments, an imaging mask includes an optically transmissive substrate. A first patterned region is formed on the substrate, and a second patterned region is formed on the substrate that is proximate to the first patterned region, the first patterned region and the second patterned region each having a plurality of optically transmissive and optically attenuating regions formed on the mask. An optical compensation region is positioned proximate to at least one of the first patterned region and the second patterned region that is configured to change a phase of the illumination radiation incident on the at least one of the first patterned region and the second region by altering an optical property of the substrate.
US08062811B2
A mask comprises a channel region half-exposure mask structure, a drain mask structure, and a source mask structure, wherein the channel region half-exposure mask structure comprises a channel region peripheral half-exposure mask structure, which extends from a portion that corresponds to a channel region of the TFT and is outside the portion. According to the present invention, problems such as a connection of the source/drain and a disconnection of the active layer in the channel region can be effectively prevented.
US08062810B2
The method of manufacturing a semiconductor device has deciding an amount of a correction of a mask pattern for a size of an active region of a semiconductor substrate, correcting the mask pattern on the basis of the decided amount of the correction, and exposing a resist film by using an exposure mask having the corrected mask pattern.
US08062809B2
Described are holographic storage mediums and method of making holographic storage mediums. The holographic storage mediums may have write components that bind to the matrix to form a pattern in the media. The holographic storage mediums may also be rewriteable.
US08062798B2
A fuel cell generator including a housing defining a plurality of chambers including a generator chamber having first and second generator sections. A plurality of elongated fuel cells extend through the first and second generator sections. An oxidant supply supplies oxidant to at least one of the chambers within the housing in order to provide oxidant to one end of each of the fuel cells. A fuel distribution plenum extends transversely to the elongated fuel cells and is located between the first and second generator sections. The fuel distribution plenum distributes fuel to the first and second generator sections in opposing directions within the generator chamber.
US08062789B2
A lithium secondary battery including a positive electrode, a negative electrode, a separator for separating the positive and negative electrodes, and a non-aqueous electrolyte. The separator includes a porous film formed of a mixture of a ceramic material and a binder, and the binder is formed of acrylic rubber having a three-dimensional crosslink structure. The separator provides excellent safety characteristics such as resistance to a short circuit and thermal resistance. Also, the separator improves a high-rate discharge characteristics and increases the life span.
US08062786B2
Disclosed herein is a cylindrical secondary battery constructed in a structure in which a crimping region, at which a cap assembly is mounted to the open upper end of a cylindrical container having an electrode assembly mounted therein, is formed at the upper end of the container, wherein the crimping region is constructed in a structure in which the upper end of the crimping region is gently bent at a predetermined radius of curvature (R), such that the crimping region surrounds a gasket located at the inside of the crimping region, the bent front end extends inward, such that the bent end presses the gasket, and an inclination of a predetermined angle is formed at the sidewall of the crimping region, such that the upper part of the crimping region is directed inward. According to the secondary battery of the present invention, the sealability of the gasket is improved, and external impacts are partially absorbed by the inclination formed at the crimping region. Consequently, the deformation of the crimping region is minimized, whereby the leakage of the electrolyte is prevented, and the safety of the battery is greatly improved.
US08062785B2
In a battery module including a plurality of batteries 40 stored in a housing, each of the batteries 40 includes an electrode portion 16 protruding from a battery case 5, a base 30A is arranged on a side of the electrode portions 16 so that the base 30A is in contact with the battery cases 5, and the electrode portions 16 are inserted in through holes 36 provided in the base 30A. Connection portions 320 connected to the electrode portions 16 are formed on upper surfaces of the electrode portions 16. A connection terminal 32 for connecting the batteries 40 in parallel is formed in a region on the base 30A in which the connection terminal 32 does not cover the through holes 36. The connection terminal 32 is connected to the connection portions 320 by fusible links 320A straddling the through holes 36.
US08062773B2
Some embodiments provide a compound represented by Formula 1: wherein R1, R2, R3, R6, R7, and R8 are independently selected from the group consisting of H, optionally substituted C1-12 alkyl, optionally substituted phenyl, optionally substituted carbazolyl, optionally substituted diphenylamine and optionally substituted diphenylaminophenyl; provided that: at least one of R1, R2, and R3 is selected from optionally substituted carbazolyl, optionally substituted diphenylamine and optionally substituted diphenylaminophenyl and at least one of R6, R7, and R8 is selected from optionally substituted carbazolyl, optionally substituted diphenylamine and optionally substituted diphenylaminophenyl; and R4 and R5 are independently selected from the group consisting of H, optionally substituted C1-12 alkyl, optionally substituted phenyl, optionally substituted diphenylamine and optionally substituted diphenylaminophenyl. Other embodiments provide an organic light-emitting diode device comprising a compound of Formula I.
US08062772B2
Some embodiments provide a compound represented by Formula 1: wherein R1, R2, R3, R6, R7, and R8 are independently selected from the group consisting of H, optionally substituted C1-12 alkyl, optionally substituted phenyl, optionally substituted carbazolyl, optionally substituted diphenylamine and optionally substituted diphenylaminophenyl; provided that: at least one of R1, R2, and R3 is selected from optionally substituted carbazolyl, optionally substituted diphenylamine and optionally substituted diphenylaminophenyl and at least one of R6, R7, and R8 is selected from optionally substituted carbazolyl, optionally substituted diphenylamine and optionally substituted diphenylaminophenyl; and R4 and R5 are independently selected from the group consisting of H, optionally substituted C1-12 alkyl, optionally substituted phenyl, optionally substituted diphenylamine and optionally substituted diphenylaminophenyl. Other embodiments provide an organic light-emitting diode device comprising a compound of Formula I.
US08062762B2
A plywood comprising plys of Paulowina wood combined with plys of other hardwoods. The resulting Paulowina based plywood panels are lightweight, approximately 40% lighter than ordinary plywood. This reduction in weight when used for construction of Recreational vehicles (RV's), Campers, Tractor-trailer box sides, Ocean Shipping boxes, Crates, and Steamer trunks will reduce associated fuel consumption by reducing the overall weight of the cargo, and can lower employee related injury. The resulting Paulowina based plywood panels will reduce work place injury (lower back pain, herniated disks, hernia, etc.) resulting in lower healthcare premiums for both employees and employers. The shipping industry that supply cargo shipping boxes also demand that a lightweight construction material be used for goods that are sent by air cargo, land cargo, rail, and sea cargo in order to conserve energy and the Paulowina based plywood panels are well suited for these applications.
US08062758B2
A self-stabilizing dispersion composition having a copolymer having at least one polymerizable acid-containing moiety, wherein the at least one acid-containing moiety is at least partially neutralized before or during polymerization, and at least one hydrophobic moiety. A process for producing such compositions is also provided, as well as a process for encapsulating water-insoluble actives in such copolymers.
US08062751B2
The present invention discloses a method for forming a low biofouling filtration membrane. First, an ozone treatment is performed to a fluorine-based porous membrane to introduce peroxides on surface. Afterwards, a first grafting polymerization is initiated from the peroxides, and functional monomers are polymerized to introduce halide groups on surface. Finally, a second grafting polymerization is initiated from the halide groups, and macro-monomers are polymerized to introduce zwitterionic group on surface, so as to form the low biofouling filtration membrane.
US08062746B2
A fiber strand comprising at least one fiber at least partially coated with a composition formed from at least one rosin, at least one cationic lubricant, at least one film forming material, at least one organosilane coupling agent, and at least one dispersion of polymeric particles. A fiber strand comprising at least one fiber at least partially coated with a composition formed from components comprising at least one rosin, at least one polymeric lubricant, at least one film forming material, at least one organosilane coupling agent, and at least one dispersion of polymeric particles. A fiber strand comprising at least one fiber at least partially coated with a starch-free composition comprising at least one rosin, at least one cationic lubricant, at least one film forming material, and at least one organosilane coupling agent. A fiber strand comprising at least one fiber at least partially coated with a starch-free composition comprising at least one rosin, at least one polymeric lubricant, at least one film forming material, and at least one organosilane coupling agent. A fiber strand comprising at least one fiber at least partially coated with a composition comprising at least one rosin, at least one silyated polyamine, at least one film forming material, and at least one organosilane coupling agent. Also provided are fabrics and composite materials comprising at least one of these fiber strands.
US08062744B2
A fluoropolymer coated film comprising polymeric substrate film and fluoropolymer coating on the polymeric substrate film. The fluoropolymer coating comprises fluoropolymer selected from homopolymers and copolymers of vinyl fluoride and homopolymers and copolymers of vinylidene fluoride polymer blended with compatible adhesive polymer comprising functional groups selected from carboxylic acid, sulfonic acid, aziridine, anhydride, amine, isocyanate, melamine, epoxy, hydroxy, anhydride and mixtures thereof. The polymeric substrate film comprises functional groups on its surface that interact with the compatible adhesive polymer to promote bonding of the fluoropolymer coating to the substrate film.
US08062738B2
Disclosed are a heat transfer medium and a heat transfer method that uses the heat transfer medium. The heat transfer medium comprises a light-transparent substrate coated with a plurality of nano particles. The nano particles absorb light incident thereon to thereby produce heat, which is transferred to a target object to be heated. Nano particles can be applied onto a target object. After heating, the particles are removed by etching. Nano particles can be selectively applied to the light-transparent substrate or directly to a target object to be heat so as to localize heat-production and thus heat selective portions of the target object.
US08062735B2
Retroreflective material is used to create security features in secure documents. Retroreflective material in the document or sheets used for document creation is laser engraved to create optically variable images, identification quality grayscale images, different directional images viewable at corresponding angles of incidence, multidimensional images, and floating images. High refractive index glass beads are selectively applied to areas of a document surface using a variety of techniques. The beads may be applied in the form of a pre-determined or personalized pattern.
US08062733B2
A high-silica glass sheet has an average thickness of less than 150 microns and an average surface roughness over one or both of its two major surfaces of less than 1 nm. The glass sheet is formed using a roll-to-roll glass soot deposition and sintering process. The glass sheet may comprise a plurality of substantially parallel surface protrusions, which are visible only when a major surface of the glass sheet is viewed at an angle sufficiently removed from normal incidence.
US08062730B2
A light diffusion film includes a thermoplastic resin, a surface of the light diffusion film has a roughness (Ra) of about 0.5 to about 3 μm and a height distribution index (HDI) of about 3 to about 8 μm, and the light diffusion film has a retardation of not more than about 25 nm.
US08062729B2
A polymeric material may be prepared by reacting a composition that includes polyol, polyisocyanate, and polyorganosiloxane having functional groups capable of reacting with the polyisocyanate, wherein the polymeric material has a surface which includes raised microdomains.
US08062720B1
Embodiments of the invention are directed to a printing member for imaging with an inkjet printer using pigment-based aqueous inkjet ink. The printing member may include a substrate and a hydrophilic coating layer. The coasting layer may include acidic colloidal silica whose particles have an elongated shape, a hydrophilic polymer and a crosslinking agent.
US08062715B2
Direct-metal deposition (DMD), preferably under closed-loop control, is used to fabricate alloy-variant material structures which provide a combination of desirable physical and mechanical properties. Use of the invention facilitates the production of high-strength, high-wear, and impact-resistant structures which decrease the likelihood of erosion, heat checking and brittle failure in injection molds, die casting, thixomolding and other, more exotic tooling. The invention uses DMD to deposit a first material or alloy in an area exposed to high wear, such as the tooling gate area, with a second material or alloy being used elsewhere in the tool for greater impact resistance. Advantageously, the areas may be of a user-defined thickness to further improve longevity. The resulting composite material structure has mechanical properties (i.e., yield strength, hardness and abrasion resistance) which exceed that of the homogeneous compositions currently used for mold materials, thereby enhancing productivity while improving part quality in these and other applications.
US08062710B2
A method for manufacturing a carpet material that typically includes applying a coating to a substrate where the coating includes the reaction product of a B-side that includes an esterified vegetable oil-based polyol and a catalyst and an A-side that includes an isocyanate and the reaction product of a B-side that includes a vegetable oil-based polyol and a catalyst and an A-side that includes an isocyanate. The polyols may optionally be blown, oxylated, and/or neutralized.
US08062709B2
A process for preparing polyurethane carpet backings uses a filled polyurethane-forming composition that contains a mixture of certain metal acetylacetonate and sulfur-containing organotin catalysts. The mixture of catalysts is particularly beneficial in instances where the composition is processed at temperatures of above 30 to about 500 C, as long pot life is provided together with a rapid thermally-induced cure.
US08062696B2
Disclosed is a front substrate of a plasma display panel and fabricating method thereof, by which color temperature, color purity, and contrast of PDP are enhanced. The present invention includes an upper dielectric layer containing a colorant therein. And, the present invention includes the step of forming an upper dielectric layer having a colorant added thereto.
US08062691B2
A non-metallic medical device treated with a antimicrobial agents is provided. Different combinations of antimicrobial agents can be used for different types of non-metallic medical devices depending on the types of infections related to each device. The combination of different antimicrobial substances has a synergistic effect against certain bacteria and fungi. An antimicrobial agent can be used to treat a non-metallic medical device by mixing the antimicrobial agent with an acid solution and glycerol and exposing the non-metallic medical device to the resulting mixture such that an enough of the antimicrobial agent binds to a portion of the non-metallic medical device to inhibit the growth of bacterial and fungal organisms.
US08062684B2
A general object of the present invention is to utilize “delayed dilution” of a concentrated extract to provide a beverage brewing system which immediately (upon customer selection) provides selective dilution (based on individual consumers selections) of a fresh-brewed coffee extract after the extract has been allowed to brew and held as an extract before dilution. It is also a general object of the present invention to utilize the undiluted extract to mix and dissolve other beverage compounds to make flavored coffees, cappuccinos, lattes, and the like. “Delayed mixing” and/or “delayed filtering” may also be utilized.
US08062681B2
A method for supplementing the levels of select amino acids in ruminants is provided. Amino acids are susceptible to microbial degradation in the rumen, where the relative susceptibility of an amino acid oligomer is determined primarily by its solubility in the rumen fluid. A method for designing and preparing microbial resistant amino acid oligomers based on relative solubility is also provided. Various compositions containing amino acids are described and shown to resist microbial degradation in ruminants.
US08062680B2
Phytoceutical compositions for the prevention and treatment of circulatory disorders, feminine endocrine disorders, and dermal disorders. A specific combination of extracts of plants is taught, as well as principles for varying the formulations based on categorizing plants into one of three groups, Energy, Bio-Intelligence, and Organization and selecting several plants from each group. Such combinations have synergistic effects, with minimal side effects.
US08062678B2
This is about a type of Piper laetispicum C.DC. extract and the preparation method thereof as well as the application of the extract in preparing drugs, healthcare products and food additives for treating and/or preventing diseases related to monoamine transmitters such as 5-hydroxytryptamine, noradrenaline and dopamine. The extract is obtained through impregnating or percolating at normal temperature or ≦70° C., or is obtained through supercritical fluid extraction method, and in comparison with the existing reflux method, it has higher alkaloid content and higher biological activity.
US08062665B2
Disclosed are novel pharmaceutical compositions containing 3′-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid bis-(monoethanolamine) (eltrombopag olamine) and processes for preparing the same.
US08062662B2
A liposome composition having a compound entrapped in a supersaturated solution and method for preparing such a composition are described.
US08062661B2
Methods of debriding a skin wound are provided. Embodiments of the subject methods include contacting the skin wound with a hydrogel patch debridement composition to debride the wound. Also provided are systems and kits for use in practicing the subject methods.
US08062660B2
A delivery device including at least one stinging capsule and methods of use are described.
US08062654B2
The present invention relates to fiber compositions comprising gels or hydrogels. The invention further relates to the composition of a gel or hydrogel loaded biodegradable fiber and methods of fabricating such fibers. The present invention further provides tissue engineering and drug-delivery compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The invention also relates to methods of manipulating the rate of therapeutic agent release by changing both the biodegradable polymer properties as well as altering the properties of the incorporated gel or hydrogel.
US08062651B1
A composition for attracting male pink hibiscus mealybugs which contains a carrier material or carrier and effective amount of (R)-lavandulyl (S)-2-methylbutanoate and (R)-maconelliyl (S)-2-methylbutanoate. Also a method for attracting male pink hibiscus mealybugs to an object or area, which method involves treating said object or area with effective amount of (R)-lavandulyl (S)-2-methylbutanoate and (R)-maconelliyl (S)-2-methylbutanoate. Cyclobutanes, 2,2-dimethyl-3-(1-methylethylidene)cyclobutanes, having the formula: wherein R1 is hydrogen, a C1-11 straight or branched alcohol, aldehyde, alkyl, ether (e.g. methanol, ethanal, 4-methylhexane, heptyloxymethane), or esters thereof with a C1-10 saturated or unsaturated, straight or branched acid (e.g., formic acid, acetic acid, 2-methylbutyric acid, 3-methyl-2-butenoic acid) and R2 is hydrogen, methyl, C1-10 saturated or unsaturated, straight or branched alkyl (e.g. hexane, isopropenyl, 4-methyl-4-pentene). A method of disrupting male pink hibiscus mealybug mating with female pink hibiscus mealybugs, involving exposing a pink hibiscus mealybug population to a composition containing a pink hibiscus mealybug mating disrupting effective amount of (R)-lavandulyl (S)-2-methylbutanoate and (R)-maconelliyl (S)-2-methylbutanoate, and optionally a carrier material or carrier.
US08062648B2
The present invention relates to a composition which comprises as active ingredients a combination of melatonin, ginkgo biloba and biotin. The composition is particularly suitable for producing formulations for topical application in the hair.
US08062628B2
This invention relates generally to an underarm hygiene product having the form of a deodorant patch between a top carrier sheet and a bottom carrier sheet. Deodorant patches dissolve upon contact with the underarm skin and provide a discreet, portable method of remaining fresh in any time or place. Convenient one time dispensing by a flat patch eliminates the need for bulky containers and provides an elegant solution to limitations on quantities of personal care products during airline flights while away from home. This invention also relates to a method of producing the underarm hygiene product.
US08062627B2
A method and composition are disclosed utilizing the pure (R,R) isomer of formoterol, which is a potent bronchodilator with reduced adverse effects, a low incidence of the development of tolerance and an increased duration of action, as compared to racemic formoterol.
US08062625B2
The invention relates to a method for predicting the efficacy of a cancer immunotherapy of an individual with respect to clinical benefit, which comprises the following steps: —providing a blood sample of said individual, —(a1) determining the number of lymphocytes in the blood of said individual, and/or (a2) determining the number of neutrophils in the blood of said individual, and —(b1) identifying the individual as having a predictive clinical benefit from the immunotherapy, if the number Of lymphocytes is below or equal to a lymphocyte baseline level of 1.4 to 1.8×109 per liter blood, especially below or equal to 1.6×109 per liter blood; or (b2) identifying the individual as having a predictive clinical benefit from the immunotherapy, if the number of neutrophils is below or equal to a neutrophil baseline level of from 4.0 to 6.0×109 per liter blood, especially below or equal to 5.0×109 neutrophils per liter blood; or (b3) identifying the individual as not having a predictive clinical benefit, if the number of lymphocytes is above a lymphocyte baseline level of 1.4 to 1.8×109 per liter blood, especially above 1.6×109 per liter blood and the number of neutrophils is above a neutrophil baseline level of from 4.0 to 6.0×109 per liter blood, especially above 5.0×109 neutrophils per liter blood.
US08062618B2
A diesel exhaust aftertreatment system and method are provided. The system includes a lean NOx trap for reducing NOx and a transition metal-exchanged zeolite booster catalyst positioned downstream from the lean NOx trap for further reducing NOx. The lean NOx trap includes a NOx adsorbent material and one or more platinum group metals, and has a platinum group metal loading of less than about 90 g/ft3. The aftertreatment system provides high NOx conversion over a broad temperature range without the use of ammonia as a major reductant.
US08062611B2
A fluid processing device is provided that includes a substrate, a plurality of fluid retainment regions formed in or on the substrate, and a barrier at least partially separating two or more of the fluid retainment regions. The barrier includes a mixture of a sequestering material and a reaction component. The reaction component can be at least one of a reactant, a reagent, a catalyst, an initiator, a promoter, a cofactor, an enzyme, a salt, or a combination thereof. The sequestering material can be a porous material, a dissolvable material, or both.
US08062609B2
A flow cytometer is provided which includes an interrogation flow cell and a plurality of assay fluidic lines extending into the interrogation flow cell. A method of operating such a flow cytometer includes priming the interrogation flow cell with a sheath fluid and injecting different assay fluids into a flow of the sheath fluid through the plurality of fluidic lines. A fluidic line assembly is provided which includes a plurality of capillary tubes coupled to a base section configured for coupling to an interrogation flow cell assembly of a flow cytometer. The capillary tubes are dimensionally configured such that when the fluidic line assembly is arranged within the flow cytometer and fluid is dispensed from one or more of the capillary tubes at a given pressure differential with respect to an encompassing sheath fluid within the interrogation flow cell the fluid is substantially centrally aligned within the interrogation flow cell.
US08062605B2
A cooling system for use in a shell-type reactor includes vertically extending double tubes with an inner tube and an outer tube closed at its lower end. The system also includes a distributor for supplying a fluid cooling medium into the upper end of the inner tubes and a horizontally extending plate, which on its upper surface includes at least two upwardly open, parallel grooves. Two adjacent grooves are separated by a common inner wall. At least one outer tube, having an upper end, is disposed in each groove, through the plate. Each outer tube is tightly welded to the plate on the groove base. The upper, open side of each groove is closed with a lid, so that each groove forms a collector for discharging the cooling medium from the outer tubes. Each inner tube opens through the lid into a distributor and is tightly attached to the lid.
US08062599B2
A catalyst cooled is employed for converting oxygenates to light olefins. The catalyst becomes spent as deposits from the reaction clog up pores on the catalyst surface. A portion of the spent catalyst is regenerated in a regenerator and a portion is circulated back to contact more of the oxygenate feedstream. A catalyst cooler attached to the reactor can cool the spent catalyst circulated through the cooler before the spent catalyst contacts more of the oxygenate feedstream. In an embodiment, all of the spent catalyst that enters the catalyst cooler is withdrawn from the bottom of the catalyst cooler.
US08062596B2
The present invention relates to a nanoparticle sensor which is capable to identify an existence/nonexistence, a concentration, a size distribution and a component of the nanoparticles using an electrode pair having a separated distance of a nano-gap, in which the nanoparticle sensor includes a unit element configured with a plurality of unit electrodes electrically operated independently from each other and detects the nanoparticles based on the number of the unit electrodes electrically changed due to the nanoparticles captured into the nano-gap. The nanoparticle sensor of the present invention can detect the component, the size, the size distribution and the concentration of the nanoparticles by single measurement, have high reliability and regeneration while reducing a detection time by statistical method via a plurality of electrode pairs having the nano-gap, and detect even very low concentration of nanoparticles.
US08062594B2
A fluid handling system adapted to provide storage and supply of a number of liquid solutions to an automatic clinical analyzer having three different bottle-like containers, a collapsible plastic-metal-plastic pouch having a mouth-like opening, a fitment to be sealed within mouth-like opening a septum within the fitment, and open meal band or cap to seal the septum into the fitment.
US08062589B2
An enclosure covers a UV lamp and has a mechanically-adjustable opening for changing an amount of the UV radiation being emitted from the enclosure, and an ozone-creating passageway receives the radiation being emitted from the enclosure. A method includes producing ozone-generating radiation, mechanically attenuating the ozone-generating radiation, and mixing the attenuated ozone-generating radiation with air to produce ozone. The method may include powering a lamp for emitting ozone-producing radiation, and adjusting an amount of ozone produced by the ozone-producing radiation by rotating a first opening with respect to a second opening.
US08062585B2
A method includes releasing mercury in devices requiring mercury, in particular fluorescent lamps. The method includes the use of manganese-mercury compositions.
US08062577B2
A high-temperature, heat-resistant fill material is disclosed. The high-temperature, heat-resistant fill material includes an alumina refractory waste material having one or more of a used alumina-magnesium-carbon material, a used high-alumina material and a used fused-grain alumina material is disclosed. A method for method for manufacturing a material is also disclosed.
US08062574B2
A method of manufacturing a polylactic acid resin injection molded article, having the step (1): a step of melt-kneading a polylactic acid resin composition containing a polylactic acid resin and a specified organic crystal nucleus agent, while contacting the composition with a supercritical fluid; and step (2): a step of filling the melted product obtained in step (1) in a die to mold with injection-molding. The manufacturing method of the present invention is used as an advantageous technique as compared with the technique of achieving satisfactory moldability by the addition of plasticizer in the field, for example, which requires a polylactic acid resin molded article having high rigidity.
US08062568B2
A method for manufacturing a nano pattern writer includes forming one or more grooves on a first layer, depositing a substance on the first layer to form a film on the first layer, polishing the film on the first layer to thereby form a patterned film that fills the one or more grooves on the first layer, placing a second layer over the patterned film to thereby form a layered structure interposing the patterned film between the first layer and the second layer, and removing a part of the first layer and the second layer to thereby expose portions of the patterned film.
US08062567B2
A process for manufacturing organic fibers containing an inorganic component comprising the steps of: (1) preparing an inorganic spinnable sol solution; (2) mixing the inorganic spinnable sol solution, a solvent capable of dissolving the inorganic spinnable sol solution, and an organic polymer capable of being dissolved in the solvent to prepare a spinning solution; and (3) spinning the spinning solution to form the organic fibers containing an inorganic component composed of an inorganic gel and the organic polymer, is disclosed. The inorganic spinnable sol solution preferably has a weight average molecular weight of 10,000 or more, and the inorganic spinnable sol solution is preferably prepared from a material containing a metal alkoxide having an organic substituent. According to the process of the present invention, organic fibers containing an inorganic component having an improved mechanical strength can be produced by mixing an inorganic component into an organic component, and a nonwoven fabric containing the fibers can be provided.
US08062565B2
A non-woven material, that can be formed into an acoustic ceiling tile, is provided. The material includes a substantially planar and self-supporting core of an inorganic base fiber and a synthetic thermal bonding fiber. The synthetic thermal bonding fiber preferably has an increased bonding surface area that improves adhesion and porosity to provide a base mat or core with a low density to provide sound absorption required by an acoustic ceiling tile.
US08062562B2
A cellulose ester film exhibiting: a free volume radius of 0.25 to 0.31 nm and a half-width of 0.04 to 0.1 nm, the free volume radius and the half-width being determined by positron annihilation lifetime spectroscopy; and Ro of 0 to nm and Rt of −30 to +20 nm, Ro and Rt being defined by the following equations: Equation (a): Ro=(nx−ny)×d; Equation (b): Rt=((nx+ny)/2−nz)×d (Ro: in-plane retardation, Rt: retardation in the thickness direction of the film, nx: in-plane refractive index in slow axis direction, ny: in-plane refractive index in fast axis direction, nz: refractive index in the thickness direction of the film (refractive indexes being measured at wavelength of 590 nm), d: thickness of the film (nm)).
US08062559B2
A composite lithium compound having a mixed crystalline structure is provided. Such compound can be formed by heating a lithium, iron, phosphorous and carbon mixed compound with another metal compound together. The resulting mixed metal crystal can exhibit superior electrical property and is a better cathode material for lithium secondary batteries.
US08062557B2
Thermoplastic resin composition containing 18-80 weight % of a polyamide 6 resin with specific viscosity number and specific ratio of terminal carboxyl groups content to terminal amino groups content (component (A)); 5-25 weight % of a hydrogenated product of a block copolymer having a vinyl aromatic compound polymer block and a conjugated diene compound polymer block (component (B)); 3-15 weight % of a graft-modified hydrogenated product of such block copolymer (component (C)), said hydrogenated product being graft-modified with maleic anhydride in an amount of 2.6-5.0 weight % based on 100 weight % of said graft-modified hydrogenated product; 1-5 weight % conductive carbon black with specific BET specific surface area and specific DBP oil absorption (component (D)); 10-30 weight % talc having a specific average particle diameter (component (E)); 0.1-2 weight % of a phosphonite compound (component (F)); 0.5-5 weight % of an ethylene-vinyl alcohol resin (component (G)); 0-1 weight % of a pentaerythritol based phosphite (component (H)).
US08062554B2
Apparatus and methods according to various aspects of the present invention may operate in conjunction with composite matrix material and reinforcement material, such as nanostructures. The nanostructures may be evenly dispersed and/or aligned in the matrix material through application of an electromagnetic field, resulting in a nanocomposite material. In one embodiment, the nanocomposite material is suitable for large scale processing.
US08062544B2
Deicing compositions comprised of hydroxyl-containing organic compounds and/or organic acid salts are disclosed.
US08062540B2
A natural leather is treated with a tanning agent, a re-tanning agent, a dye and a greasing agent, wherein a treatment agent for inhibiting the generation of formaldehyde and acetaldehyde from the natural leather is added to the greasing step so that the natural leather is impregnated with the treatment agent. The treatment agent includes a hydrazide compound optionally together with sodium hydrogen sulfite.
US08062536B2
A method for depositing dielectric material into gaps between wiring lines in the formation of a semiconductor device includes the formation of a cap layer and the formation of gaps into which high density plasma chemical vapor deposition (HDPCVD) dielectric material is deposited. First and second antireflective coatings may be formed on the wiring line layer, the first and second antireflective coatings being made from different materials. Both antireflective coatings and the wiring line layer are etched through to form wiring lines separated by gaps. The gaps between wiring lines may be filled using high density plasma chemical vapor deposition.
US08062535B2
Method for producing a probe for atomic force microscopy with a silicon nitride cantilever and an integrated single crystal silicon tetrahedral tip with high resonant frequencies and low spring constants intended for high speed AFM imaging.
US08062534B2
An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.
US08062524B2
An integrated oxidation ditch comprises a number of oval channels. There are two or more circular zones in the central island of the oxidation ditch, wherein, the two circular zones are tangential to the inner wall or share the inner wall with an adjacent channel. Wastewater of different zones is connected with others. The center island is used sufficiently in the oxidation ditch and all the channels and the deposition zone or the deposition zone and an anaerobic zone, inner/outer re-circulation zone are integrated together. So the oxidation ditch improves space utilization efficiency and reduces the land and cost.
US08062521B2
A filtering medium and method for removing contaminants from an organic-based feed stream which includes the use of a layer of ceramic filter units having a plurality of elliptical or trisoidal openings extending therethrough to filter organic-based feed streams and to provide liquid distribution upstream of the catalyst beds.
US08062513B2
In one embodiment an automated peritoneal dialysis (“APD”) machine includes: at least one pump; a logic implementer storing a plurality of therapy prescriptions by which to operate the at least one pump, each therapy prescription pre-approved for a particular patient; and an input device operating with the logic implementer to allow the patient to select one of the therapy prescriptions for a particular therapy. In another embodiment, the input device operating with the logic implementer allows a doctor/clinician to select or approve one of the therapy prescriptions to be run on the APD machine. In a further embodiment, the logic implementer is programmed to select or suggest one of the therapy prescriptions to be run on the is APD machine.
US08062510B2
A method for extracting hydrocarbons from a vessel by displacement. The method including the displacement of a hydrocarbon source with a material of different density and recovery of the hydrocarbons from the vessel. Additionally, a method for extracting hydrocarbons from a vessel by gas displacement through chemical introduction. The method including introduction of hydrochloric acid and sodium bicarbonate into a vessel, production of carbon dioxide from the reaction of the hydrochloric acid and the sodium bicarbonate, displacement of a hydrocarbon source inside the vessel, and recovery of the hydrocarbon source from the vessel.
US08062509B2
One exemplary embodiment can be a process for desorbing one or more polynuclear aromatics from at least one fraction from a hydrocracking zone using an adsorption zone. The adsorption zone can include first and second vessels. Generally, the process includes passing the at least one fraction from an effluent of the hydrocracking zone through the first vessel containing a first activated carbon, and passing a petroleum fraction boiling in the range of about 200-about 400° C. for desorbing the one or more polynuclear aromatics through the second vessel containing a second activated carbon.
US08062507B2
A process for stripping gases from catalyst material in which catalyst travels down baffles at a first acute angle and then at a second acute angle on the same baffle. Traveling down the baffle at the second angle assures the catalyst will cross a downcomer channel and land on an adjacent baffle.
US08062493B2
The present disclosure generally relates to systems, arrangements, and techniques for electrophoretic deposition of a plating material on a surface of a substrate. Example systems may include one or more of a substrate for receiving the plating material, a gel, a source element, and a conductive layer.
US08062489B2
An object of the present invention is to provide a method for stably forming an artificial lipid membrane while suppressing the leakage and evaporation of an electrolytic solution. The present invention is an artificial lipid membrane forming method for forming an artificial lipid membrane using an artificial lipid membrane forming apparatus. The artificial lipid membrane forming apparatus comprises a first chamber, a second chamber, a dividing wall, and an artificial lipid membrane forming portion. Each of the first chamber and the second chamber has a capacity of not smaller than 10 pl and not larger than 200 μl. The artificial lipid membrane forming method of the present invention comprises the steps of: preparing the artificial lipid membrane forming apparatus; adding to the first chamber a first electrolytic solution having a viscosity of not lower than 1.3 mPa·s and not higher than 200 mPa·s; adding a lipid solution to the artificial lipid membrane forming portion; adding to the second chamber a second electrolytic solution having a viscosity of not lower than 1.3 mPa·s and not higher than 200 mPa·s; and forming the artificial lipid membrane.
US08062487B2
A wafer supporting device of a sputter apparatus includes a pedestal positioned in a sputtering chamber and used to load a wafer for sputtering, a deposition ring having a recess positioned on a peripheral portion of the pedestal, and a cover ring positioned on the pedestal and the deposition ring. The cover ring has a gate corresponding to the recess.
US08062478B2
Emulsions are provided which are useful in imparting water-resistance to gypsum wood fiber products. In one embodiment, the emulsions comprise a wax or a combination of waxes, an alkyl phenol, at least one surfactant, Polynaphthalenesulfonic acid, and an alkali metal hydroxide. In another embodiment, the emulsions comprise a wax or a combination of waxes, an alkyl phenol, at least one surfactant, polynaphthalenesulfonic acid, an alkali metal hydroxide, and a complexed starch.
US08062475B2
To provide a detaching method capable of detaching a first substrate and a second substrate bonded together through a pressure-sensitive adhesive film, while minimizing the physical external load imposed on these substrates. A method for detaching a first substrate and a second substrate bonded together by a pressure-sensitive adhesive film comprising a pressure-sensitive adhesive polymer having dispersed therein a thermally decomposable metal hydroxide or metal salt hydrate filler, the method comprising a step of heating the pressure-sensitive adhesive film to a temperature capable of causing decomposition and dehydration of the metal hydroxide or metal salt hydrate, thereby accelerating the detachment.
US08062470B2
A method and an apparatus are proposed for simultaneously coating the inner walls of a plurality of hollow containers, such as bottles, with fluid-impermeable barrier layers applied by a PECVD method with the use of transversal antennas capable of creating plasma having density increased in the vicinity of the inner walls of the containers. The barrier-layer application period is divided into a coating period and a noncoating cooling period, with RF energy constantly maintained under working conditions with shunting thereof from the coating station to the dummy loads during noncoating periods used for cooling the plastic containers. The apparatus comprises a vacuum chamber with a conveyor that transports the containers in a preoriented state for interaction with a plurality of aligning elements that can be inserted into the container openings for subsequent fixation at equal distances in positions aligned with the antennas that can be inserted into the containers for generation of the coating-applying plasma.
US08062453B2
A method of winding fibers on a mandrel, the wound fibers being in tension, includes providing a source of fibers, imposing a torque on the source that resists dispensing the fibers from the source to exert a tension on the fibers, adding ultra-violet sensitive material that is polymerized by exposure to ultra-violet light to a resin matrix, impregnating dispensed fibers with the additive containing resin matrix, rotating a mandrel to wind the impregnated fibers on the mandrel, the rotation of the mandrel acting to overcome the torque on the source and putting the fibers in tension, and in situ, quasi instantaneously polymerizing the additive containing resin matrix on the mandrel by means of exposing the additive containing resin matrix to ultra-violet light for a selected period of time, such polymerization acting to lock in the tension in the fibers at the time of polymerization. A rail gun fabricated by means of the above method is further included.
US08062443B2
Embodiments of the present subject matter provide an improved percussion primer composition and improved hot-wire igniter acceptor, wherein lead styphnate is replaced with a lead-free material, 4,6-dinitro-7-hydroxybenzofuroxan, potassium salt (KDNP). Embodiments of the percussion primer composition include KDNP, a sensitizer, an oxidizer, calcium silicide, a fuel, and a binder. Sensitizers may include tetracene. Oxidizers may include alkali or alkaline earth nitrates, oxides, or peroxides (such as barium nitrate). Fuel materials may include metals, metal sulfides, or other non-metallic materials. Common binders may include nitrocellulose based shellacs, gum arabic/poly vinyl alcohol mixtures, and guar gum/poly vinyl alcohol mixtures. Embodiments of the hot-wire igniter device include a bridgewire, an acceptor, and an output, where KDNP is the acceptor. Power supply may be in the form of constant current/voltage or current flow from a capacitor discharge. Certain embodiments utilize a variety of output formulations, such as BKNO3, black powder, and Red Dot double base propellant.
US08062439B2
A magnesium alloy sheet having an adequate strength and an excellent bendability is provided along with a method of manufacturing such an alloy sheet. The method comprises, rolling a magnesium alloy sheet through a reduction roll, the alloy thereof containing about 0.1-10.0 mass % of Al and about 0.1-4.0 mass % of Zn, wherein the magnesium alloy sheet has a surface temperature of about 100° C. or below at the time just before it is fed in the reduction roll, and the reduction roll has a surface temperature in the range of about 100° C. to 300° C. Particularly, when executing multipass rolling, at least the last pass is accomplished in non-preheat rolling wherein the magnesium alloy sheet and the reduction roll have specified surface temperatures, respectively.
US08062430B2
Filters used in the beverage industry fouled by polyphenol-protein complexes and carbohydrate polymers can be cleaned by treating the filters either with the following methods: Solubilization of at least part of the carbohydrate polymers followed by a treatment of the resulting polyphenol protein complex with an oxidative chemical. Treatment of the fouled filters through a back-wash method using an oxidative chemical. In both cases it is not necessary to rinse the membranes after cleaning with a reductive chemical.
US08062427B2
Apparatus for metering and vaporizing a particulate material, includes a metering device for metering particulate material including: a reservoir for receiving particulate material; a housing having an internal volume and having first and second openings; a rotatable shaft disposed in the internal volume, the shaft having a smooth surface and a circumferential groove; a structure disposed in the reservoir for delivery and cooperating with the rotating shaft for fluidizing particulate material and transporting it from the reservoir into the groove; the shaft and internal volume cooperating such that particulate material is transported by the groove; a scraper cooperates with the groove to dislodge particulate material retained therein and fluidize the scraped particulate material, and deliver metered amounts of particulate material through the second opening; and a flash evaporator that receives and flash vaporizes the metered particulate material.
US08062420B2
Described are nonlinear optical (NLO) crystals, including aluminum-borate NLO crystals, that have low concentrations of contaminants that adversely affect the NLO crystal's optical properties, such as compounds that contain transition-metal elements and/or lanthanides, other than yttrium, lanthanum, and lutetium. Some NLO crystals with low concentrations of these contaminants are capable of second harmonic generation at very short wavelengths. Also described are embodiments of a method for making these NLO crystals. Some embodiments involve growing a single NLO crystal, such as an aluminum-borate NLO crystal, from a mixture containing a solvent that is substantially free of harmful contaminants. The described NLO crystals can be used, for example, in laser devices.
US08062411B2
The invention relates to an adsorptive filtering material endowed with integrated particle- and/or aerosol-protection and with protective performance with regard to biological and/or chemical noxiants, in particular biological and/or chemical warfare agents, the adsorptive filtering material having a multilayered construction comprising a support layer, an adsorptive layer associated to and preferably fixed to the support layer, and optionally a covering layer disposed on that side of the adsorptive layer that is remote from the support layer, wherein the adsorptive filtering material is additionally equipped with a particle- and/or aerosol-filtering layer. The adsorptive filtering material is particularly useful in NBC protective materials of any kind (as in protective apparel for example) and for producing filters.
US08062407B2
A relatively simple and inexpensive method for the synthesis of silver nanoparticles within a short period of time using a household microwave or the like is provided. The energy needed to heat the synthesis reaction is minimized and the organic reducing reagents of the prior art are replaced with natural products such as purified carbohydrates (e.g., glucose, sucrose, fructose, galactose, ribose, lactose) or their readily available and inexpensive forms (e.g., high fructose corn syrup, sucrose syrup). The resulting nanoparticles are purified from the remaining silver ion which is then recaptured for the safe disposal of the waste reaction mixture.
US08062400B2
A drum is for a rotary separator including a shaft rotatable about a central axis. The drum includes an inner drum member having inner and outer circumferential surfaces and being disposed generally about the shaft such that a first flow passage is generally defined between the inner drum member inner surface and the shaft. The inner drum inner surface is configured to separate liquids from a fluid flow contacting the surface. An outer drum member has inner and outer circumferential surfaces and is disposed generally about the inner drum member such that a second flow passage is generally defined between the outer drum member inner surface and the inner drum member outer surface, the second flow passage being generally coaxial with the first flow passage. Further, the outer drum inner surface is also configured to separate liquids from a fluid flow contacting the surface.
US08062397B2
An air filter assembly for an evaporative emissions control canister used with an internal combustion engine fuel system. The assembly includes: a housing having: an air inlet formed in an upper portion of the housing; and an air outlet; and; a baffle disposed within the housing. The baffle extends vertically downward from the air inlet in the upper portion of the housing towards a bottom portion of the housing. The baffles forming a plurality of vertically extending channels interconnected through a horizontally interconnecting channel formed between a bottom edge of the baffle and the bottom portion of the housing. A first one of the vertically extending channel receives air entering the housing from the air inlet. The air passes downwardly in the first one of the channels, then passing laterally outwards through the horizontally interconnecting channel towards sidewalls of the housing, then passing upwardly through a second one of the vertically extending channels, and then finally exiting the housing through the air outlet. A filter structure is disposed in the second one of the vertically extending channels.
US08062396B2
The purpose of this invention is to provide a pleated-type filter used for an apparatus for collecting dust that is optimally designed and to provide the apparatus for collecting dust using the filter, wherein the pleated-type filter can keep the resistance to its ventilation low when the filter is installed in the apparatus for collecting dust so that the pleats are directed vertically, and wherein the area for installing the main bodies of the pleated-type filters can be reduced as much as possible.The ratio of the apertures of the pleats (P/H) that is defined by the intervals (P) between the crests of adjacent pleats of the main body and the heights (H) of its pleats ranges from 0.1 to 0.3. The ratio is determined based on the relationship between the area for installing the pleated-type filters and the ratio of the apertures of the pleats (P/H). This is done by using the resistance to ventilation of the contaminated filtering cloth, which resistance corresponds to a coefficient of resistance that is caused by a filtering cloth and residual dust that cannot be shaken off from the filter by means of the shaking-off operation.
US08062394B2
An abrasive product includes a plurality of abrasive particles and a resin cured with a polythiol group. A method of preparing the abrasive product includes contacting the plurality of abrasive particles with a curable composition that includes a resin and a polythiol group, and curing the curable composition to produce the abrasive product. A method of abrading a work surface includes applying an abrasive product to a work surface in an abrading motion to remove a portion of the work surface. A curable composition includes a formaldehyde resin and a polythiol group. A formaldehyde resin is crosslinked by a polythiol group. A method of crosslinking the formaldehyde resin includes reacting the polythiol group with the formaldehyde resin.
US08062392B2
The present invention discloses a system for biomass treatment which addresses the need to find economical solutions to transport biomass. In the present invention, small, distributed gasifiers convert the biomass into synthesis gas (“syngas”). The syngas is then transported via a pipeline network to a central fuel production facility.
US08062390B2
Provided are methods for binding particulate solids in a polymer fiber matrix utilizing composite waste products. A mixture of composite waste products and particulate solids is formed into solid products to create degradation resistant solid units which capture the particulate solids.
US08062389B2
Low vapor pressure compound-based fuels are provided. These fuels are useful in catalytic burner systems that can be used to disperse fragrances, insecticides, insect repellants (e.g., citronella), aromatherapy compounds, medicinal compounds, deodorizing compounds, disinfectant compositions, fungicides and herbicides.
US08062375B2
The present invention provides an expandable fusion device capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. In one embodiment, the fusion device includes a body portion, a first endplate, and a second endplate, the first and second endplates capable of being moved in a direction away from the body portion into an expanded configuration or capable of being moved towards the body portion into an unexpanded configuration. The fusion device is capable of being deployed and installed in both configurations.
US08062372B2
A spinal fusion device abutting and fixed between adjacent vertebrae. The spinal fusion device includes a support frame. The support frame has a plurality of extending bodies, each radially extending from a center of the support frame. A predetermined gap exists between every two adjacent extending bodies, receiving a bone graft.
US08062369B2
A cervical intervertebral prosthesis system includes prostheses which each have a hinge with a predefined center of hinge movement. To permit better adaptation to the different hinge radii of the cervical intervertebral disks, the cervical intervertebral prostheses of the system include at least two different prostheses with different hinge radii.
US08062362B2
An intraocular lens for implantation in a capsular bag of an eye includes an optic disposed about an optical axis and a haptic including a protruding portion disposed inside the optic. The optic has an anterior face and an opposing posterior face that are configured to provide a lens power. In response to an ocular force of the eye, the haptic transmits a force that alters one or more of a shape of the optic and an axial thickness of the optic. The protruding portion of the haptic has a refractive index that is equal to a refraction index of the optic for at least one wavelength within the visible spectrum.
US08062359B2
A connecting band for a highly flexible tissue-type heart valve having a stent with cusps and commissures that are permitted to move radially. The connecting band follows the cusps and commissures and extends outwardly. The valve is connected to the natural tissue along the undulating connecting band using conventional techniques, such as sutures. The connecting band may be a cloth-covered inner suture-permeable member and attaches to the underside of the valve at the cusps to provide support to the stent and to the outer side of the valve at the commissures. The connecting band includes commissure portions defining generally axial gaps that help permit flexing of the valve. The inner member may include one or more slits along the cusps to enhance flexibility. The inner member may further include a continuous outwardly projecting sewing ridge around its periphery which includes a series of ribs separated by grooves around the inflow edge of the cusps. The sewing ridge enables supra-annular implant of a valve constructed with the connecting band.
US08062342B2
In an exemplary embodiment, the present invention provides an orthopedic plate blocking assembly that can be used for the fixation or fastening of an orthopedic plate to bone tissue. In particular, the present invention, in one embodiment, provides an orthopedic plate having a plurality of cavities where each cavity is configured and dimensioned to receive a bone anchoring member. The orthopedic plate further provides a blocking mechanism having a plurality of blocking members that block the bone anchoring members to prevent the bone anchoring members from “backing out” of cavities once the bone anchoring members are finally seated in the cavities.
US08062335B1
A spinal system having a plate with at least one nesting point and at least one screw hole for receiving a screw. The system also includes a keel having a first and second keel wing attached to the plate and a structure having at least one screw hole, the structure configured to be placed between two vertebrae in a spine. The first and second keel wing are configured with at least one screw hole each which correspond to the at least one screw hole of the plate and the at least one screw hole of the structure. The first and second keel wing are configured with a first and second bottom portion, and the first and second bottom portions having a first and second cup for receiving a portion of the screw and the first and second bottom portions being adapted to lock the screws from backing out.
US08062334B2
A bone anchor is described having pre-attached suture material. After insertion, lateral wings can be deployed on the bone anchor to prevent anchor pull-out. The suture may be attached at the tip of the anchor by tying it to a wire hook secured in a cavity in the anchor tip. The anchor may be inserted and deployed using an anchor inserter that is configured to apply an axial force to the anchor, thereby deforming the anchor to form the lateral wings.
US08062331B2
An internal and external medical closure system for a separation of first and second tissue portions is provided, which includes a mesh screen comprising tubular vertical risers, vertical strands with barbed filaments, and horizontal spacers connecting the risers and strands in a grid-like configuration. An optional perimeter member partly surrounds the screen and can comprise a perimeter tube fluidically coupled with the vertical risers to form a tubing assembly. Various input/output devices can optionally be connected to the perimeter tube ends for irrigating and/or draining the separation according to methodologies of the present invention. Separation closure, irrigation and drainage methodologies are disclosed utilizing various combinations of closure screens, tubing, sutures, fluid transfer elements and gradient force sources. The use of mechanical forces associated with barbed strands for repositionably securing separated tissues together is disclosed. The use of same for eliminating or reducing the formation of subcutaneous voids or pockets, which can potentially form hematoma and seroma effects, is also disclosed. Further disclosed are alternative embodiment medical closure screen installation systems and methods.
US08062322B2
A hair transplant apparatus and a method for placing hair grafts into pre-made wounds capture a hair graft into a hair graft chamber readily aligned for implantation into the human scalp. The hair graft can be placed into the hair graft chamber manually or mechanically (e.g., by vacuum). A hair transplant apparatus includes a housing and a sliding rod within the housing. When the sliding rod is away from an open distal end of the housing in a first position, a hair graft can be placed into the spacing between an end of the rod and the open distal end of the housing. In a second position, the rod is advanced so the end of the rod becomes substantially flush with the distal end of the housing, thereby pushing the hair graft out of the housing and into the pre-made wound. Advantageously, the housing is aligned with the direction of the pre-made wound allowing the hair graft to slide easily into the pre-made wound without damage. Extraneous forces are eliminated by the alignment of the housing to the wound, thus creating a linear path for the hair graft to move without obstruction to finally settle in the scalp wound.
US08062321B2
The catheter apparatus may be used to assist in creating a fistula between two adjacent blood vessels. The apparatus includes a catheter for inserting into a first blood vessel which lies adjacent to a second blood vessel, the catheter having a plurality of openings through which a physician may navigate a piercing tool. The physician maneuvers the tip of the catheter to a position within the first blood vessel adjacent to a portion of the first blood vessel wall in which the physician intends to create an opening. The physician may then rotate the piercing tool within the catheter and extend the piercing tool through one opening at a time, without rotating the catheter, until the physician chooses an opening that is properly aimed at the second blood vessel. Such a configuration allows for a wide arc of potential firing space.
US08062320B2
A puncture device is constituted such that a plunger (2) is provided with a lever (3) which is partially restricted in rotation, and a forward urging force is obtained by a contraction restorative force of a tension spring (4), and the tension spring (4) is again expanded with the lever (3) as a leverage when the plunger (2) further moves forward due to its inertia from a position where no urging force is not applied, and the plunger (2) is urged backward by a restorative force of the re-expansion. Further, a puncture needle cartridge is provided with a lancet body (203) having a puncture needle, and a puncture needle holder (201) in which the lancet body (203) is movably stored, and further, the lancet body (203) has an arm means (302) and the puncture needle holder (201) contains a to-be-latched means (303) that cooperates with the arm means (302). Thereby, the fabrication process is simplified, and plural times of punctures of the puncture needle is prevented, and further, the puncture speed is controlled, and moreover, the used puncture needle is discarded safely.
US08062317B2
A rotatable thrombectomy wire for breaking up thrombus or other obstructive material including an inner core composed of a flexible material and an outer wire surrounding at least a portion of the inner core. The outer wire has a sinuous shaped portion at a distal region. The inner core limits the compressibility of the outer wire. The outer wire is operatively connectable at a proximal end to a motor for rotating the wire to macerate thrombus.
US08062315B2
A variable parietal/visceral pleural coupling may be utilized to create an air-tight seal in the pleural space between the parietal and visceral pleura. This coupling may be utilized to create a seal for other implantable devices.
US08062314B2
A medical method includes sliding two substantially straight unconnected arms over a fold of body tissue such that a first arm contacts a first portion of the fold and a second arm contacts a second portion. Then, each arm is bent completely through the fold such that both of the arms compress the portions of the fold into contact with each other. Another method includes releasably coupling first and second substantially linear arms to a bridge, each of the arms having a substantially straight sliding portion and a bendable piercing portion. The arms are slid over opposing sides of two body tissue layers, the first arm sliding over the first layer and the second over the second layer. While the sliding portions of the arms remain substantially straight, each piercing portion is bent completely through the adjacent layer and halfway through the other layer to compress the two layers together.
US08062313B2
A device and method for treatment of atrioventricular regurgitation comprises a suturing device. The suturing device is configured to be introducible, via blood vessels leading to the heart, to two leaflets of the atrioventricular valve between the atrium and a corresponding ventricle of the heart. The suturing device is configured for binding together the two leaflets along the free edges of the leaflets. A method of using the device includes inserting the suturing device into a catheter, introducing the catheter to the heart and positioning a distal end of the catheter close to two leaflets of an atrioventricular valve, capturing the free edges of the two leaflets with the suturing device in its open state, binding together the two leaflets by transition of the suturing device into its closed state, and retracting the catheter from the heart. As a result, the closing of the valve is improved.
US08062309B2
Methods, apparatus, and systems for occluding a multiplicity of parallel membranes, such as found in a patent foramen ovale (PFO). Methods, apparatus, and systems include the use of a positioning device that can be seated on the limbus of the septum secundum (SS). The positioning device includes a piercing member that can pierce the SS and septum primum (SP). The positioning device also includes a fastening member that can engage the SS and SP to fasten the tissues and occlude a PFO.
US08062303B2
A system and method for inserting an implant into a cavity is disclosed, which may include advancing an implant insertion instrument toward a pair of adjacent bodies, the implant insertion instrument having two opposed ramps, wherein each ramp has a distal tip and wherein the longitudinal axes of the opposed ramps are separated by an initial angle; inserting the distal tips of the opposed ramps between the adjacent bodies, thereby creating an initial interbody cavity between the adjacent bodies; expanding the interbody cavity while maintaining the initial angle between the longitudinal axes of the opposed ramps; placing the implant in a final location between the adjacent bodies; transferring a compressive force urging the adjacent bodies together from the opposed ramps to the implant; and extracting the implant insertion instrument from the interbody cavity.
US08062299B2
A series of instruments (30, 80, 120, 210, 510, 550) are provided for direct-anterior and oblique-anterior disc space and end plate preparation. The instruments (30, 80, 120, 210, 510, 550) provide precise guidance for channel formation in the vertebral endplates by guiding rotating and bladed cutting instruments (122, 250, 580). Instrumentation (550) for oblique-anterior disc space preparation includes compound angulation to account for the angle of approach to the spine and the angulation between adjacent vertebrae. Methods and techniques for use of the instruments (30, 80, 120, 210, 510, 550) are also described.
US08062297B2
A bone fixation apparatus comprising a shape memory effect material includes a bridge member having at least three sides and an open center portion. Each of the bridge member sides defines a curve having a respective first radius when the shape memory effect material is in a first state, and a respective second radius larger than a corresponding first radius when the shape memory effect material is in a second state. Elongate members are connected to, and extend outwardly from, the bridge member. Each of the elongate members are connected to the bridge member at an approximate intersection of a respective two of the sides, such that each elongate member is subject to a force from each of two intersecting sides, and moves toward the open center portion of the bridge member when the shape memory effect material changes from the second state to the first state.
US08062294B2
An orthopaedic implant provides a simple yet effective retention system requiring no additional components beyond the implant and the associated fastener(s). A plurality of anti-rotation protrusions on the fastener or screw head that match recesses in the implant. The protrusions engage the recesses to prevent the fastener from reversing direction, thereby assuring that the associated fastener does not backout during normal motion of the spine and other anatomical structures. A land on the fastener screw thread assures the fastener will not disengage from the implant should it strip out of the bone. Preventing the fastener from backing out assures it will not detach from the implant or staple, assuring that the implant will remain in place until all fasteners in the system have catastrophically failed. The anti-backout features of the invention provide feedback as they engage, allowing the surgeon to move quickly when placing a fastener without the concern for inadvertent over-tightening. Although ideally suited to a spinal correction system such as a cervical plate, the invention is applicable to other orthopedic devices, including plates and staples for other applications.
US08062281B2
The invention relates to a device for injecting liquid, comprising a piece of tubing on which there is situated at least a first liquid occlusion system. According to the invention, a regulation system is situated upstream from the first occlusion system, the two systems defining an intermediate segment in which the pressure, in the absence of injection, is greater than the pressure that exists downstream from the first occlusion system so as to direct any leak of liquid from the first occlusion system downstream. The invention is applicable to a pump used for injecting contrast liquid for medical imaging.
US08062278B2
Embodiments of the present disclosure include disposable wearable absorbent articles with extensible sides. In an embodiment of the present disclosure a disposable wearable absorbent article includes a front, a back, and an extensible side configured to connect the front and the back, wherein the extensible side has a substantially laterally extensible area, which includes a first area, bounded in part by at least a portion of a longitudinally outboard side edge. An overall lateral extensibility of the first area is substantially less than an overall lateral extensibility of the substantially laterally extensible area.
US08062276B2
A reusable diaper may include an inner layer to wick moisture and an outer layer substantially impervious to liquids. A waist portion may include a corner region for securing the diaper in a desired position. The corner region may be resiliently stretchable and substantially impervious to liquids, and may include first and second layers coupled to the respective inner and outer layers. The coupled first layer and inner layer define a first seam allowance, and the coupled second layer and outer layer define a second seam allowance. The first and second seam allowances may be positioned within the corner region to help inhibit wicking of liquid through the seam allowances into the corner region. And a fluid-resistant region may be provided to help resist wicking of moisture through the inner layer past the fluid-resistant region.
US08062266B2
A vascular access device within an external environment may include a body and a septum at least partially housed within the body. Septum may at least substantially seal a lumen extending through the body. The septum may further include at least a first and a second material. At least one of the materials of the septum may be selected or adapted to resist tearing of the septum.
US08062263B2
A support system for supporting a feeding tube of a person is disclosed. The support system comprises an elongated flexible band, a disc and a sling mechanism. The elongated flexible band is adapted to circumscribe the person's body, at least partially covering abdomen region of the person. The disc is disposed on the elongated flexible band and is capable of securing the feeding tube. The sling mechanism is functionally coupled to the elongated flexible band and provides support to the feeding tube, for example, while the tube is not being used to feed a user.